Na Di
YOU?
Author Swipe
View article: Prenatal diagnosis a novel mutation in the ITGB4 gene associated with junctional epidermolysis bullosa: A Case Report
Prenatal diagnosis a novel mutation in the ITGB4 gene associated with junctional epidermolysis bullosa: A Case Report Open
View article: The Causal Pivot: A structural approach to genetic heterogeneity and variant discovery in complex diseases
The Causal Pivot: A structural approach to genetic heterogeneity and variant discovery in complex diseases Open
View article: Membrane-spanning 4 domains subfamily A member 4A inhibition promotes M1 macrophage polarization and enhances anti-gastric cancer immune response
Membrane-spanning 4 domains subfamily A member 4A inhibition promotes M1 macrophage polarization and enhances anti-gastric cancer immune response Open
Objective: The immunosuppressive tumor microenvironment (TME) limits the treatment effectiveness of immunotherapy in gastric cancer (GC). This study investigated the role of membrane-spanning four domains subfamily A member 4A (MS4A4A) in …
View article: Token Cleaning: Fine-Grained Data Selection for LLM Supervised Fine-Tuning
Token Cleaning: Fine-Grained Data Selection for LLM Supervised Fine-Tuning Open
Recent studies show that in supervised fine-tuning (SFT) of large language models (LLMs), data quality matters more than quantity. While most data cleaning methods concentrate on filtering entire samples, the quality of individual tokens w…
View article: Jumonji domain-containing protein 6 promotes gastric cancer progression: Modulating immune evasion through autophagy and oxidative stress pathways
Jumonji domain-containing protein 6 promotes gastric cancer progression: Modulating immune evasion through autophagy and oxidative stress pathways Open
Objective: Immune response is crucial in the development of gastric cancer (GC), and Jumonji domain-containing protein 6 (JMJD6) plays an important role in mediating GC cell behavior. This study aims to elucidate the mechanisms through whi…
View article: The Development of a Genetically Engineered Multivalent Subunit Vaccine Against “Struck”, “Braxy”, Lamb Dysentery and Enterotoxaemia in Sheep
The Development of a Genetically Engineered Multivalent Subunit Vaccine Against “Struck”, “Braxy”, Lamb Dysentery and Enterotoxaemia in Sheep Open
View article: A salt-tolerant growth-promoting phyllosphere microbial combination from mangrove plants and its mechanism for promoting salt tolerance in rice
A salt-tolerant growth-promoting phyllosphere microbial combination from mangrove plants and its mechanism for promoting salt tolerance in rice Open
View article: The Causal Pivot: A Structural Approach to Genetic Heterogeneity and Variant Discovery in Complex Diseases
The Causal Pivot: A Structural Approach to Genetic Heterogeneity and Variant Discovery in Complex Diseases Open
We present the Causal Pivot (CP) as a structural causal model (SCM) for analyzing genetic heterogeneity in complex diseases. The CP leverages one established causal factor to detect the contribution of a second suspected cause. Specificall…
View article: Genome-wide identification and evolution of the SAP gene family in sunflower (<i>Helianthus annuus</i> L.) and expression analysis under salt and drought stress
Genome-wide identification and evolution of the SAP gene family in sunflower (<i>Helianthus annuus</i> L.) and expression analysis under salt and drought stress Open
Stress-associated proteins (SAPs) are known to play an important role in plant responses to abiotic stresses. This study systematically identified members of the sunflower SAP gene family using sunflower genome data. The genes of the sunfl…
View article: Use of Flurbiprofen Ester in 4-Dimensional Hysterosalpingography: Does Flurbiprofen Ester Relieve Pain During an Infertility Evaluation?
Use of Flurbiprofen Ester in 4-Dimensional Hysterosalpingography: Does Flurbiprofen Ester Relieve Pain During an Infertility Evaluation? Open
Objective: The purpose of this study was to determine the analgesic effect of a flurbiprofen ester injection via continuous intravenous drip during transvaginal 4-dimensional hysterosalpingography (TVS 4D-HyCoSy). Methods: Two hundred thir…
View article: Efficacy and safety of XELOX combined with neoadjuvant radiotherapy verus neoadjuvant chemotherapy in locally advanced gastric cancer
Efficacy and safety of XELOX combined with neoadjuvant radiotherapy verus neoadjuvant chemotherapy in locally advanced gastric cancer Open
Objective The work aimed to compare the efficacy and safety of XELOX regimen combined with neoadjuvant radiotherapy (CRT) and neoadjuvant chemotherapy (CT) in locally advanced gastric cancer. Methods The clinical data of patients with loca…
View article: Use of Flurbiprofen ester in 4-dimensional hysterosalpingography : could it effectively relieve pain during infertility examination?
Use of Flurbiprofen ester in 4-dimensional hysterosalpingography : could it effectively relieve pain during infertility examination? Open
Objective The purpose of this article is to investigate the analgesic effect of flurbiprofen ester injection continuous intravenous drip in transvaginal 4-dimensional hysterosalpingography (TVS 4D-HyCoSy). Methods Two hundred thirty patien…
View article: Preliminary Investigation into Ultrasound and MRI Presentation of Large-Cell Neuroendocrine Carcinomas of the Uterine Cervix
Preliminary Investigation into Ultrasound and MRI Presentation of Large-Cell Neuroendocrine Carcinomas of the Uterine Cervix Open
Objective: The aim of this study was to analyze the ultrasound and MRI features of eight patients with cervical large-cell neuroendocrine carcinoma to improve awareness of this disease among sonographers, radiologists, and clinicians. Meth…
View article: Comparative study of Curcumin and Lucentis on retinal neovascularization
Comparative study of Curcumin and Lucentis on retinal neovascularization Open
Introduction To investigate the effect of Curcumin on retinal neovascularization in mice with oxygen-induced lesions. Methods 7-day-old (P7) C57/BL6J mice were randomly divided into control group, OIR group, DMSO group, 100 mg/kg, 50 mg/kg…
View article: Prognostic Value of Tumor-microenvironment-associated Genes in Ovarian Cancer
Prognostic Value of Tumor-microenvironment-associated Genes in Ovarian Cancer Open
Background: Ovarian cancer (OV) is the fifth leading cause of cancer death among women. Growing evidence supports a key role of the tumor microenvironment in the growth, progression, and metastasis of OV. However, the prognostic effects of…
View article: Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu2O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton
Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu2O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton Open
It was shown that some nanomaterials may have anticancer properties, but lack of selectivity is one of challenges, let alone selective suppression of cancer growth by regulating the cellular microenvironment. Herein, we demonstrated for th…
View article: Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu2O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton
Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu2O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton Open
It was shown that some nanomaterials may have anticancer properties, but lack of selectivity is one of challenges, let alone selective suppression of cancer growth by regulating the cellular microenvironment. Herein, we demonstrated for th…
View article: Measurement of Uterine Cavity Shape of Adult Female on Coronal Section by Three-dimensional Ultrasound
Measurement of Uterine Cavity Shape of Adult Female on Coronal Section by Three-dimensional Ultrasound Open
Objective: To describe the measurement of uterine cavity shape on coronal section by three-dimensional ultrasound in Chinese adult female population. Methods: A cross-sectional observational study including 172 adult females with normal ut…
View article: Transforming growth factor-β1 induces connective tissue growth factor expression and promotes peritoneal metastasis of gastric cancer
Transforming growth factor-β1 induces connective tissue growth factor expression and promotes peritoneal metastasis of gastric cancer Open
Transforming growth factor-β1 (TGF-β1) is involved in human cancer development and progression. Nonetheless, the role of TGF-β1 as regards peritoneal metastasis of gastric cancer has not been completely characterized. In the present study,…
View article: The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo
The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo Open
View article: Prognostic Value of Genes Related with Tumor Microenvironment in Ovarian Cancer
Prognostic Value of Genes Related with Tumor Microenvironment in Ovarian Cancer Open
Background Ovarian cancer (OV) is the fifth leading cause of cancer death among females. Growing evidence supports a key role of tumor microenvironment in growth, progress, and metastasis of OV. However, the impacts of gene expression sign…
View article: Knowledge, practice and attitude towards HPV vaccination among college students in Beijing, China
Knowledge, practice and attitude towards HPV vaccination among college students in Beijing, China Open
This cross-sectional study aimed to assess the knowledge, practice and attitude towards HPV vaccination among college students in Beijing, China. Furthermore, the factors influencing vaccination were analyzed. The data were collected via s…
View article: Could semiquantitative analysis of real-time ultrasound elastography distinguish more liver parenchyma alterations of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome?
Could semiquantitative analysis of real-time ultrasound elastography distinguish more liver parenchyma alterations of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome? Open
Semiquantitative real-time ultrasound elastography analysis could distinguish liver parenchyma alterations in patients with polycystic ovary syndrome more sensitively. The diagnostic value of the proposed method for nonalcoholic fatty live…
View article: Could semiquantitative analysis of real-time ultrasound elastography distinguish more liver parenchyma alterations of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome?
Could semiquantitative analysis of real-time ultrasound elastography distinguish more liver parenchyma alterations of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome? Open
Objective: Nonalcoholic fatty liver disease is the commonest diffuse liver disease, of which women with polycystic ovary syndrome are at an increased risk. The aim of the present study was to assess the diagnostic value of the semiquantita…
View article: Could semiquantitative analysis of real-time ultrasound elastography distinguish more liver parenchyma alterations of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome?
Could semiquantitative analysis of real-time ultrasound elastography distinguish more liver parenchyma alterations of nonalcoholic fatty liver disease in patients with polycystic ovary syndrome? Open
Objective: Nonalcoholic fatty liver disease is the commonest diffuse liver disease, of which women with polycystic ovary syndrome are at an increased risk. The aim of the present study was to assess the diagnostic value of the semiquantita…
View article: Close correlation between hyperandrogenism and insulin resistance in women with polycystic ovary syndrome—Based on liquid chromatography with tandem mass spectrometry measurements
Close correlation between hyperandrogenism and insulin resistance in women with polycystic ovary syndrome—Based on liquid chromatography with tandem mass spectrometry measurements Open
Background To investigate the correlation between hyperandrogenism (HA) and insulin resistance (IR) in women with polycystic ovary syndrome (PCOS) by measuring serum total testosterone (TT) using a liquid chromatography and tandem mass spe…
View article: Gut microbiota plays a role in the development of polycystic ovary syndrome and its metabolic disorders
Gut microbiota plays a role in the development of polycystic ovary syndrome and its metabolic disorders Open
View article: Gastric cancer‐derived exosomes promote peritoneal metastasis by destroying the mesothelial barrier
Gastric cancer‐derived exosomes promote peritoneal metastasis by destroying the mesothelial barrier Open
An intact mesothelium serves as a protective barrier to inhibit peritoneal carcinomatosis. Cancer‐derived exosomes can mediate directional tumor metastasis; however, little is known about whether gastric cancer‐derived exosomes will destro…
View article: COMBINED EFFECT OF ORGANIC AND BIOFERTILIZER ON HERB YIELD AND ESSENTIAL OIL PRODUCTION OF ORIGANUM VULGARE L. PLANTS UNDER SANDY SOIL CONDITIONS
COMBINED EFFECT OF ORGANIC AND BIOFERTILIZER ON HERB YIELD AND ESSENTIAL OIL PRODUCTION OF ORIGANUM VULGARE L. PLANTS UNDER SANDY SOIL CONDITIONS Open
This study was carried out on Origanum vulgare L. plant during the two successive seasons of 2013 and 2014, at the Experimental Station of Medicinal and Aromatic Plants of Sekem Company, Belbis desert-EL Sharkiya, Egypt.The aim of this res…