Yi Ouyang
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Author Swipe
View article: Evaluation of the multiple HPV-based “screen and triage” algorithms in real-world settings of rural China
Evaluation of the multiple HPV-based “screen and triage” algorithms in real-world settings of rural China Open
Objective: Drawbacks of human papillomavirus (HPV) primary screening, including high referral rates and low specificity, highlight the necessity for triage strategies to balance the screening benefits with potential harms. Methods: A cross…
View article: Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer
Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer Open
BACKGROUND Metastasis is the main reason leading to death in colorectal cancer (CRC) and about 25% of CRC patients developed metastasis when first diagnosed. Thus, unveiling biomarkers of CRC metastasis is of great significance. AIM To rev…
View article: The Role of IL-10 in Regulating Inflammatory Pathways and Cancer Risk
The Role of IL-10 in Regulating Inflammatory Pathways and Cancer Risk Open
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine that plays a crucial role in regulating immune responses by preventing the immune system from overreacting. It maintains immune homeostasis by suppressing the production of …
View article: RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer
RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer Open
Cervical cancer metastasis is characterized by the systemic spread of tumor cells. However, the underlying mechanism remains incompletely understood. Herein, we demonstrate that RAB33A promoted metastasis by enhancing RhoC accumulation and…
View article: Anxiety disorders and adhesive capsulitis: a bidirectional Mendelian randomization study
Anxiety disorders and adhesive capsulitis: a bidirectional Mendelian randomization study Open
Background Previous epidemiological investigations and related research efforts consistently have outlined an observable association between anxiety disorders and adhesive capsulitis (AC). However, the intricate nature of the causal connec…
View article: Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells
Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells Open
Background The purpose of present study was to reveal the molecular mechanisms responsible for both adipogenic differentiation and dedifferentiation of mesenchymal stem cells (MSCs). Methods Microarray data GSE36923 were obtained from the …
View article: Additional file 2 of Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells
Additional file 2 of Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells Open
Additional file 2. TFs and their descriptions
View article: Additional file 1 of Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells
Additional file 1 of Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells Open
Additional file 1. miRNAs and their degree scores
View article: The effect of chemotherapy cycles on treatment outcomes in small cell neuroendocrine carcinoma of uterine cervix
The effect of chemotherapy cycles on treatment outcomes in small cell neuroendocrine carcinoma of uterine cervix Open
Objectives: To investigate the effect of chemotherapy cycles on survival outcomes in small cell neuroendocrine carcinoma of cervix (SCNEC). Methods: Clinical records of 103 biopsy-proven SCNEC were identified from Sun Yat-sen University Ca…
View article: SHMT2 promotes tumor growth through VEGF and MAPK signaling pathway in breast cancer.
SHMT2 promotes tumor growth through VEGF and MAPK signaling pathway in breast cancer. Open
Cancer cells modulate their metabolic activities to adapt to their growth and proliferation. Despite advances in breast cancer biology having led to the widespread use of molecular targeted therapy and hormonal drugs, the molecular mechani…
View article: Identification of an IDO1‐based immune classifier for survival prediction of upper tract urothelial carcinoma
Identification of an IDO1‐based immune classifier for survival prediction of upper tract urothelial carcinoma Open
The limited response rate of immunotherapy in upper tract urothelial carcinoma (UTUC) might be attributed to additional immunosuppressive mechanisms in vivo. As a promising immune checkpoint target, the expression and prognostic role of in…
View article: Upregulation of SHMT2 Promotes Tumor Growth and Poor Prognosis of Breast Cancer through Activating VEGF and MAPK Signaling Pathway
Upregulation of SHMT2 Promotes Tumor Growth and Poor Prognosis of Breast Cancer through Activating VEGF and MAPK Signaling Pathway Open
Background: Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in Serine/glycine metabolism. SHMT2 is very important for tumor cell growth and proliferation as well as metabolism. Here, we investigated the regulatory effects of SHMT…
View article: Structural Evolution of Polyglycolide and Poly(glycolide<i>-co-</i>lactide) Fibers during In Vitro Degradation with Different Heat-Setting Temperatures
Structural Evolution of Polyglycolide and Poly(glycolide<i>-co-</i>lactide) Fibers during In Vitro Degradation with Different Heat-Setting Temperatures Open
The structural evolution of polyglycolide (PGA) and poly(glycolide-co-lactide) (P(GA-co-LA)) with 8% LA content fibers with different heat-setting temperatures was investigated during in vitro degradation using WAXD, SAXS, and mechanical p…
View article: Multiomics analysis of tumor mutational burden across cancer types
Multiomics analysis of tumor mutational burden across cancer types Open
Whether tumor mutational burden (TMB) is related to improved survival outcomes or the promotion of immunotherapy in various malignant tumors remains controversial, and we lack a comprehensive understanding of TMB across cancers. Based on t…
View article: Long-Term Outcomes of Three-Dimensional High-Dose-Rate Brachytherapy for Locally Recurrent Early T-Stage Nasopharyngeal Carcinoma
Long-Term Outcomes of Three-Dimensional High-Dose-Rate Brachytherapy for Locally Recurrent Early T-Stage Nasopharyngeal Carcinoma Open
Background: Brachytherapy (BT) is one of the techniques available for retreatment of patients with locally recurrent nasopharyng eal carcinoma (rNPC). In this study, we evaluated the treatment outcome and late toxicities of three-dimension…