Nabila Youssouf
YOU?
Author Swipe
View article: Moderate agreement between the spot albumin‒Creatinine ratio (ACR) and urine albumin (UA) among virally suppressed adults living with HIV in botswana: a cross sectional study
Moderate agreement between the spot albumin‒Creatinine ratio (ACR) and urine albumin (UA) among virally suppressed adults living with HIV in botswana: a cross sectional study Open
UA and ACR show moderate agreement overall. Optimal UA cutoffs differ slightly by sex, suggesting tailored thresholds may improve detection. Future studies should explore clinical indication(s) for using the ACR versus UA levels among PLWH.
View article: Barriers to Blood Pressure Control in Treated Patients Attending Public Primary Healthcare Clinics in Gaborone, Botswana
Barriers to Blood Pressure Control in Treated Patients Attending Public Primary Healthcare Clinics in Gaborone, Botswana Open
Background High blood pressure (BP) is prevalent and uncontrolled in many low‐ and middle‐income countries (LMICs). Uncontrolled BP causes cardiovascular diseases (CVDs) and kidney disease. The high morbidity and mortality caused by uncont…
View article: Integrated Hypertension-HIV Care in Botswana: Mixed-Methods Evaluation of Determinants of Success in an Implementation Trial
Integrated Hypertension-HIV Care in Botswana: Mixed-Methods Evaluation of Determinants of Success in an Implementation Trial Open
Due to the success of HIV treatment, people living with HIV (PWH) have aged to develop chronic conditions. InterCARE is evaluating the integration of hypertension treatment into HIV care in Botswana. This involves adapting the Electronic H…
View article: Household economic impact of HIV‐associated cryptococcal meningitis in five countries in Southern and Eastern Africa
Household economic impact of HIV‐associated cryptococcal meningitis in five countries in Southern and Eastern Africa Open
Introduction HIV‐associated cryptococcal meningitis is the second leading cause of AIDS‐related mortality. Cryptococcal meningitis is a poverty‐related disease and the majority of cases occur in settings where resources are limited and acc…
View article: Personalised risk-prediction tools for cryptococcal meningitis mortality to guide treatment stratification in sub-Saharan Africa: a prognostic modelling study based on pooled analysis of two randomised controlled trials
Personalised risk-prediction tools for cryptococcal meningitis mortality to guide treatment stratification in sub-Saharan Africa: a prognostic modelling study based on pooled analysis of two randomised controlled trials Open
National Institute for Health Research.
View article: Recent Antiretroviral Therapy Initiation Is Associated With Increased Mortality Risk in Human Immunodeficiency Virus–associated Cryptococcal Meningitis: An Analysis of Clinical Trial Data From Africa
Recent Antiretroviral Therapy Initiation Is Associated With Increased Mortality Risk in Human Immunodeficiency Virus–associated Cryptococcal Meningitis: An Analysis of Clinical Trial Data From Africa Open
Mortality from cryptococcal meningitis was higher in recent ART initiators. ART interruption in this group may lead to improved outcomes.
View article: Designing an implementation science clinical trial to integrate hypertension and cardiovascular diseases care into existing HIV services package in Botswana (InterCARE)
Designing an implementation science clinical trial to integrate hypertension and cardiovascular diseases care into existing HIV services package in Botswana (InterCARE) Open
Background Despite success in HIV treatment, diagnosis and management of hypertension (HTN) and cardiovascular disease (CVD) remains suboptimal among people living with HIV (PLWH) in Botswana, with an overall HTN control of only 19% compar…
View article: Quantitative outcomes of a type 2 single arm hybrid effectiveness implementation pilot study for hypertension-HIV integration in Botswana
Quantitative outcomes of a type 2 single arm hybrid effectiveness implementation pilot study for hypertension-HIV integration in Botswana Open
View article: Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis Open
BACKGROUND: Cryptococcal meningitis is a leading cause of human immunodeficiency virus (HIV)-related death in sub-Saharan Africa. Whether a treatment regimen that includes a single high dose of liposomal amphotericin B would be efficacious…
View article: AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study
AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study Open
INTRODUCTION: Cryptococcal meningitis is responsible for around 15% of all HIV-related deaths globally. Conventional treatment courses with amphotericin B require prolonged hospitalisation and are associated with multiple toxicities and po…
View article: A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration.
A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration. Open
Cryptococcal meningitis accounts for 15% of all HIV-related deaths. The overall number of cryptococcal meningitis cases has remained relatively stable in many low-to-middle income countries (LMICs) despite increasing roll-out of antiretrov…
View article: High prevalence of albuminuria among adult males living with HIV in Botswana
High prevalence of albuminuria among adult males living with HIV in Botswana Open
Chronic HIV disease is associated with a fivefold increase in albuminuria outside of sub-Saharan Africa. However, very little is known about albuminuria risk among people living with HIV (PLWH) in sub-Saharan Africa. Therefore, we conducte…
View article: A mixed methods approach identifying facilitators and barriers to guide adaptations to InterCARE strategies: an integrated HIV and hypertension care model in Botswana
A mixed methods approach identifying facilitators and barriers to guide adaptations to InterCARE strategies: an integrated HIV and hypertension care model in Botswana Open
View article: Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study
Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study Open
European and Developing Countries Clinical Trials Partnership; Swedish International Development Cooperation Agency; Wellcome Trust/UK Medical Research Council/UKAID Joint Global Health Trials; and UK National Institute for Health Research.
View article: Self-reported cardiovascular disease risk factor screening among people living with HIV vs. members of the general population in Botswana: a community-based study
Self-reported cardiovascular disease risk factor screening among people living with HIV vs. members of the general population in Botswana: a community-based study Open
Background Morbidity and mortality due to cardiovascular diseases (CVDs) are high and increasing in low- and middle-income countries. People living with HIV (PLWH) are more likely to experience CVD than members of the general population. T…
View article: Standard of care in advanced HIV disease: review of HIV treatment guidelines in six sub-Saharan African countries
Standard of care in advanced HIV disease: review of HIV treatment guidelines in six sub-Saharan African countries Open
View article: Time for a proper career pathway for clinical trial managers?
Time for a proper career pathway for clinical trial managers? Open
View article: Innovative quantitative PCR assays for the assessment of HIV-associated cryptococcal meningoencephalitis in Sub-Saharan Africa
Innovative quantitative PCR assays for the assessment of HIV-associated cryptococcal meningoencephalitis in Sub-Saharan Africa Open
Background Cryptococcal meningitis (CM) accounts for about 10-20% of AIDS-defining illnesses with a 10-week mortality rate of 25-50%. Fungal load assessed by colony-forming unit (CFU) counts is used as a prognostic marker and to monitor re…
View article: The IMPACT of COVID-19 Pandemic on CAB
The IMPACT of COVID-19 Pandemic on CAB Open
View article: Integrating community engagement activities within implementation science research projects: lessons from the InterCARE project
Integrating community engagement activities within implementation science research projects: lessons from the InterCARE project Open
View article: Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial Open
For the Chichewa, Isixhosa, Luganda, Setswana and Shona translations of the abstract see Supplementary Materials section.
View article: Sclerosingstromaltumor of the ovary (report case) N Youssouf, F Watik, S Sabir, H Boufettal, S Mahdaoui, N Samouh Gynecology Department C CHU Ibn Rochd Casablanca
Sclerosingstromaltumor of the ovary (report case) N Youssouf, F Watik, S Sabir, H Boufettal, S Mahdaoui, N Samouh Gynecology Department C CHU Ibn Rochd Casablanca Open
View article: Association of Hyponatremia on Mortality in Cryptococcal Meningitis: A Prospective Cohort
Association of Hyponatremia on Mortality in Cryptococcal Meningitis: A Prospective Cohort Open
Background Sodium abnormalities are frequent in central nervous system infections and may be caused by cerebral salt wasting, syndrome of inappropriate antidiuretic hormone secretion, or medication adverse events. In cryptococcal meningiti…
View article: Clinical trial management: a profession in crisis?
Clinical trial management: a profession in crisis? Open
Clinical trial managers play a vital role in the design and conduct of clinical trials in the UK. There is a current recruitment and retention crisis for this specialist role due to a complex set of factors, most likely to have come to a h…
View article: 525 Concurrent chemoradiotherapy followed by surgery for cervical cancer: a multicenter retrospective study of 126 cases
525 Concurrent chemoradiotherapy followed by surgery for cervical cancer: a multicenter retrospective study of 126 cases Open
Introduction/Background Cervical cancer is the third leading cause of cancer death in women worldwide. Radio-chemotherapy significantly improved overall survival rates, without recurrence, and reduced the rate of distant metastatic dissemi…
View article: 521 PAP smear screening among female patients of the ibn rochd university hospital center: a cross sectional survey
521 PAP smear screening among female patients of the ibn rochd university hospital center: a cross sectional survey Open
Introduction/Background Cervical cancer is preceded by a period of pre-invasive state, and is characterized histologically by a broad spectrum of events ranging from cellular atypia to different degrees of cervical intraepithelial neoplasi…
View article: A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration
A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration Open
Cryptococcal meningitis accounts for 15% of all HIV-related deaths [1]. The overall number of cryptococcal meningitis cases has remained relatively stable in many low-to-middle income countries (LMICs) despite increasing roll-out of antire…
View article: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial
AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial Open
Background Cryptococcal meningitis (CM) is a major cause of mortality in HIV programmes in Africa despite increasing access to antiretroviral therapy (ART). Mortality is driven in part by limited availability of amphotericin-based treatmen…
View article: AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study
AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study Open
Introduction Cryptococcal meningitis is responsible for around 15% of all HIV-related deaths globally. Conventional treatment courses with amphotericin B require prolonged hospitalisation and are associated with multiple toxicities and poo…
View article: Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial
Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial Open
Following publication of the original article [1], we have been notified that one of the author names was listed incorrectly. Both incorrect and correct author names are presented below. The original publication has been corrected.