Nadav Kislev
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View article: Advanced glycation end-products accelerate amyloid deposits in adipocyte’s lipid droplets
Advanced glycation end-products accelerate amyloid deposits in adipocyte’s lipid droplets Open
Adipose tissue dysfunction is central to insulin resistance, and the emergence of type 2 diabetes (T2D) is associated with elevated levels of carbonyl metabolites from glucose metabolism. In this study, using methylglyoxal (MGO) and glycol…
View article: Advance Glycation End-products accelerate amyloid deposits in adipocyte’s lipid droplets
Advance Glycation End-products accelerate amyloid deposits in adipocyte’s lipid droplets Open
Adipose tissue dysfunction is central to insulin resistance, and the emergence of type 2 diabetes (T2D) is associated with elevated levels of carbonyl metabolites from glucose metabolism. In this study, using methylglyoxal (MGO) and glycol…
View article: Nutrition Alters the Stiffness of Adipose Tissue and Cell Signaling
Nutrition Alters the Stiffness of Adipose Tissue and Cell Signaling Open
Adipose tissue is a complex organ composed of various cell types and an extracellular matrix (ECM). The visceral adipose tissue (VAT) is dynamically altered in response to nutritional regimens that lead to local cues affecting the cells an…
View article: How to follow lipid droplets dynamics during adipocyte metabolism
How to follow lipid droplets dynamics during adipocyte metabolism Open
Lipid droplets (LDs) are important cellular organelles due to their ability to accumulate and store lipids. LD dynamics are associated with various cellular and metabolic processes. Accurate monitoring of LD's size and shape is of prime im…
View article: MYH10 Governs Adipocyte Function and Adipogenesis through Its Interaction with GLUT4
MYH10 Governs Adipocyte Function and Adipogenesis through Its Interaction with GLUT4 Open
Adipogenesis is dependent on cytoskeletal remodeling that determines and maintains cellular shape and function. Cytoskeletal proteins contribute to the filament-based network responsible for controlling the shape of adipocytes and promotin…
View article: Exploring the Cell Stemness and the Complexity of the Adipose Tissue Niche
Exploring the Cell Stemness and the Complexity of the Adipose Tissue Niche Open
Adipose tissue is a complex organ composed of different cellular populations, including mesenchymal stem and progenitor cells, adipocytes, and immune cells such as macrophages and lymphocytes. These cellular populations alter dynamically d…
View article: MYH10 governs adipocyte function and adipogenesis through its interaction with GLUT4
MYH10 governs adipocyte function and adipogenesis through its interaction with GLUT4 Open
Adipocyte differentiation is dependent on cytoskeletal remodeling processes that determine and maintain cellular shape and function. In turn, cytoskeletal proteins contribute to the filament-based network responsible for controlling adipoc…
View article: Imaging analysis to quantitate the Interplay of membrane and cytoplasm protein dynamics
Imaging analysis to quantitate the Interplay of membrane and cytoplasm protein dynamics Open
Plasma membrane proteins are extremely important in cell signaling and cellular functions. Protein expression and localization alter in response to various signals in a way that is dependent on cell type and niche. Compartmental quantifica…