Nadia Eberhard
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View article: Patient-reported outcome measures in an outpatient parenteral antimicrobial therapy program: a prospective cohort study
Patient-reported outcome measures in an outpatient parenteral antimicrobial therapy program: a prospective cohort study Open
Objectives To evaluate the improvements in the mean Short Form-36 (SF-36) score (95% CI) from predischarge to postdischarge among prospective participants of a Swiss Outpatient Parenteral Antimicrobial Therapy (OPAT) programme using Patien…
View article: Improving antimicrobial treatment in terms of antimicrobial stewardship and health costs by an OPAT service
Improving antimicrobial treatment in terms of antimicrobial stewardship and health costs by an OPAT service Open
Purpose Outpatient parenteral antimicrobial therapy (OPAT) is a standard for antimicrobial therapy internationally. With this prospective cohort study, we aimed to assess the impact of an OPAT service as part of antimicrobial stewardship (…
View article: Patient-reported outcome measures in an outpatient parenteral antimicrobial therapy program– a prospective cohort study
Patient-reported outcome measures in an outpatient parenteral antimicrobial therapy program– a prospective cohort study Open
Objectives To evaluate the influence of our local Outpatient Parenteral Antimicrobial Therapy (OPAT) program on Health-Related Quality of Life (HRQoL) using Patient Reported Outcomes (PROs). Design Prospective cohort study. Setting A publi…
View article: Patient-reported outcome measures in an outpatient parenteral antimicrobial therapy program– a prospective cohort study
Patient-reported outcome measures in an outpatient parenteral antimicrobial therapy program– a prospective cohort study Open
Objectives Conventional perspectives that solely consider clinical outcomes and costs fail to acknowledge the patient's perspective. Outpatient Parenteral Antimicrobial Therapy (OPAT) has become a global standard in antimicrobial therapy. …
View article: Improving Antimicrobial Treatment in Terms of Antimicrobial Stewardship and Health Costs by an Opat Service a Single Centre Prospective Cohort Study
Improving Antimicrobial Treatment in Terms of Antimicrobial Stewardship and Health Costs by an Opat Service a Single Centre Prospective Cohort Study Open
Purpose : Outpatient parenteral antimicrobial therapy (OPAT) is a standard for antimicrobial therapy internationally. With this prospective cohort study, we aimed to assess the impact of an OPAT service as part of antimicrobial stewardship…
View article: Rapid antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales: an implementation study
Rapid antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales: an implementation study Open
AIMS OF THE STUDY: The goal of this descriptive study was to assess the performance as well as the extent of the clinical impact of rapid automated antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales. …
View article: Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis
Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis Open
To understand the pathophysiology of spondylodiscitis due to Staphylococcus aureus , an emerging infectious disease of the intervertebral disc (IVD) and vertebral body with a high complication rate, we combined clinical insights and experi…
View article: Intervertebral disc cell chondroptosis elicits neutrophil response in<i>Staphylococcus aureus</i>spondylodiscitis
Intervertebral disc cell chondroptosis elicits neutrophil response in<i>Staphylococcus aureus</i>spondylodiscitis Open
Objective To understand the pathophysiology of spondylodiscitis due to Staphylococcus aureus , an emerging infectious disease of the intervertebral disc (IVD) and vertebral body with a high complication rate, by combining clinical insights…
View article: Impact of an electronic alert on prescription patterns of meropenem, voriconazole and caspofungin
Impact of an electronic alert on prescription patterns of meropenem, voriconazole and caspofungin Open
Background Antimicrobial stewardship programs promote the appropriate use of antimicrobial substances through the implementation of evidence-based, active and passive interventions. We analyzed the effect of a computer-assisted interventio…
View article: Impact of PET/CT among patients with suspected mycotic aortic aneurysms
Impact of PET/CT among patients with suspected mycotic aortic aneurysms Open
Purpose To determine the impact of 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) on clinical management in patients with suspected mycotic aortic aneurysms (MAA). Materials and methods For this obs…
View article: Quantification of within-patient<i>Staphylococcus aureus</i>phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations
Quantification of within-patient<i>Staphylococcus aureus</i>phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations Open
Summary Background Difficult-to-treat infections caused by antibiotic susceptible strains have been linked with the occurrence of persisters. Persisters are a subpopulation of dormant bacteria that tolerate antibiotic exposure despite lack…
View article: Open wounds and rifampicin therapy are associated with rifampicin resistance among staphylococcal vascular graft/endograft infections
Open wounds and rifampicin therapy are associated with rifampicin resistance among staphylococcal vascular graft/endograft infections Open
Background Optimal timing for rifampicin combination therapy in patients with staphylococcal vascular graft/endograft infection (S-VGEI) is unknown. Experts recommend adding rifampicin after lowering bacterial load by surgery and wound clo…
View article: Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations
Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations Open
Dataset for the manuscript "Quantification of within‑patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations"
View article: Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations
Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations Open
Dataset for the manuscript "Quantification of within‑patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations"
View article: Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations
Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations Open
Dataset for the manuscript "Quantification of within‑patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations"
View article: Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine
Lymphocyte Subsets in HIV-Exposed Uninfected Infants: The Impact of Neonatal Postexposure Prophylaxis With Zidovudine Open
HIV-exposed, uninfected (HEU) infants receiving neonatal postexposure prophylaxis with zidovudine showed nonsignificant trends of lower CD4 and CD8 T cells as well as CD19 B cells than those who did not, suggesting toxicity that might impa…
View article: Deep infection with <i>Mycobacterium marinum</i>: successful treatment of a frequently misdiagnosed disease
Deep infection with <i>Mycobacterium marinum</i>: successful treatment of a frequently misdiagnosed disease Open
We report a rare yet typical presentation of a severe infection with Mycobacterium marinum that affected the deep structure of the hand and wrist of a 43-old fish breeder. A combination therapy of surgical debridement and antibiotic treatm…
View article: Comparison of Löwenstein–Jensen and <scp>BACTEC MGIT</scp> 960 culture for <i>Mycobacterium tuberculosis</i> in people living with <scp>HIV</scp>
Comparison of Löwenstein–Jensen and <span>BACTEC MGIT</span> 960 culture for <i>Mycobacterium tuberculosis</i> in people living with <span>HIV</span> Open
Objectives The aim of the study was to clarify how HIV infection affects tuberculosis liquid and solid culture results in a resource‐limited setting. Methods We used baseline data from the Study on Outcomes Related to Tuberculosis and HIV …
View article: Delayed Sputum Culture Conversion in Tuberculosis–Human Immunodeficiency Virus–Coinfected Patients With Low Isoniazid and Rifampicin Concentrations
Delayed Sputum Culture Conversion in Tuberculosis–Human Immunodeficiency Virus–Coinfected Patients With Low Isoniazid and Rifampicin Concentrations Open
Although low antituberculosis drug concentrations did not translate to a high proportion of patients with treatment failure, the association between low concentrations of rifampicin and isoniazid and delayed culture conversion may have imp…