Nadine Ezard
YOU?
Author Swipe
View article: Implementation and formative evaluation of a peer-led chemsex intervention targeting sexualised crystal methamphetamine and GHB use: the M3THOD study
Implementation and formative evaluation of a peer-led chemsex intervention targeting sexualised crystal methamphetamine and GHB use: the M3THOD study Open
M3THOD was valued by participants with unique information and support needs often unmet by sexual health, mental health and drug and alcohol services and reported that peers' personal experiences of chemsex facilitated rapid rapport, valid…
View article: Emergency department presentations, hospitalisations and police seizure data related to gamma‐hydroxybutyrate (GHB) in New South Wales, Australia, from 2015 to 2024
Emergency department presentations, hospitalisations and police seizure data related to gamma‐hydroxybutyrate (GHB) in New South Wales, Australia, from 2015 to 2024 Open
Background and aims Gamma‐hydroxybutyrate (GHB) is an endogenous neurochemical and illicit synthetic drug. Its precursors, gamma‐butyrolactone (GBL) and 1,4‐butanediol (1,4‐BD), are often used as substitutes. We aimed to describe GHB‐relat…
View article: Impact of dextroamphetamine substitution on the use of illicit amphetamines in adults with amphetamine dependence: a study protocol for the multicentre double blind randomised controlled trial ATLAS4Dependence
Impact of dextroamphetamine substitution on the use of illicit amphetamines in adults with amphetamine dependence: a study protocol for the multicentre double blind randomised controlled trial ATLAS4Dependence Open
Introduction There is limited evidence on how to effectively treat individuals from marginalised populations with dependence on amphetamine and/or methamphetamine (collectively referred to hereafter as amphetamine dependence). The disease …
View article: A 3-year experience of an Australian short-stay Psychiatric, Alcohol and Non-prescription Drug Assessment Unit: unit activity and the patient experience
A 3-year experience of an Australian short-stay Psychiatric, Alcohol and Non-prescription Drug Assessment Unit: unit activity and the patient experience Open
Background The Psychiatric, Alcohol and Non-Prescription Drug Assessment (PANDA) Unit was opened at St Vincent’s Hospital Sydney in 2020 to provide short-stay medical monitoring and care for people presenting to the emergency department wi…
View article: Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study
Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study Open
Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use d…
View article: The Need to Revitalise Drug Use Monitoring to Keep Pace With a More Dynamic, Digitally Enabled and Globally Connected Drug Market
The Need to Revitalise Drug Use Monitoring to Keep Pace With a More Dynamic, Digitally Enabled and Globally Connected Drug Market Open
View article: Novel psychoactive substances in Australian emergency departments: implications for public health practice from multi-centre prospective toxicosurveillance across five states, 2022–2023
Novel psychoactive substances in Australian emergency departments: implications for public health practice from multi-centre prospective toxicosurveillance across five states, 2022–2023 Open
Drug intelligence data generated in an acute harm setting such as the ED can provide early warning of drugs of concern circulating in the community, including NPS. This facilitates rapid community responses to reduce harm and inform subseq…
View article: From environmental disasters to emerging drugs; a framework to understand, map and assess drug-related early warning systems
From environmental disasters to emerging drugs; a framework to understand, map and assess drug-related early warning systems Open
Unregulated drug markets are fast expanding and increasingly mediated through digital technologies. In a context of drug prohibition, the composition, potency and effects of substances are not guaranteed which can expose people to potentia…
View article: Co-design of the Australian Prompt Response Network for a public-health focused intersectoral approach to information sharing on emerging drugs of concern
Co-design of the Australian Prompt Response Network for a public-health focused intersectoral approach to information sharing on emerging drugs of concern Open
The rapid emergence of new psychoactive substances (NPS) and other emerging drugs of concern presents a significant global public health challenge, necessitating agile and interconnected drug information systems to identify and communicate…
View article: Hydromorphone Hopes: A Qualitative Study of People Initiating Supervised Short‐Acting Injectable Opioid Treatment in Australia
Hydromorphone Hopes: A Qualitative Study of People Initiating Supervised Short‐Acting Injectable Opioid Treatment in Australia Open
Introduction A growing body of qualitative scholarship has drawn attention to aspects of supervised injectable opioid treatment (SIOT) not captured in earlier clinical trial data, identifying treatment initiation as one such area. Crucial …
View article: Characteristics of take-home fentanyl test strip use and support for drug checking services among people who use heroin in Australia: learnings for an increasingly complex drug market
Characteristics of take-home fentanyl test strip use and support for drug checking services among people who use heroin in Australia: learnings for an increasingly complex drug market Open
View article: Commentary on Young <i>et al</i> .: Clinical guidance is required for stimulant co‐prescription with opioid agonist therapy
Commentary on Young <i>et al</i> .: Clinical guidance is required for stimulant co‐prescription with opioid agonist therapy Open
View article: Bridging the evidence and the politics: Implementation trial of supervised injectable opioid treatment (SIOT) in Australia
Bridging the evidence and the politics: Implementation trial of supervised injectable opioid treatment (SIOT) in Australia Open
Supervised Injectable Opioid Treatment (SIOT) targets people experiencing opioid dependence who have not benefited from existing treatments. In this population, SIOT has been demonstrated to be efficacious and effective, yet this modality …
View article: Responding to reports of nitazene toxicity in Australia
Responding to reports of nitazene toxicity in Australia Open
View article: Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial)
Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) Open
Introduction Methamphetamine use disorder is a significant public health concern. No pharmacological treatment options currently exist for methamphetamine use disorder, and psychotherapy is only moderately effective. Preliminary evidence s…
View article: Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial)
Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) Open
Introduction Methamphetamine use disorder is a global public health concern with no approved pharmacotherapies for its treatment. One recent randomised controlled trial conducted in the USA examined a combination of bupropion and naltrexon…
View article: Exploring experiences of talk therapies among gay and bisexual men seeking to reduce or abstain from using crystal methamphetamine in the context of chemsex
Exploring experiences of talk therapies among gay and bisexual men seeking to reduce or abstain from using crystal methamphetamine in the context of chemsex Open
Introduction Some gay and bisexual men who have sex with men (GBMSM) who use drugs to enhance sex (chemsex/party and play) may experience harms and seek talk therapies. GBMSM who practice chemsex may not access drug services because of ant…
View article: Psilocybin-Assisted Psychotherapy for Methamphetamine Use Disorder: A Pilot Open-Label Safety and Feasibility Study
Psilocybin-Assisted Psychotherapy for Methamphetamine Use Disorder: A Pilot Open-Label Safety and Feasibility Study Open
View article: Lisdexamfetamine in the treatment of methamphetamine dependence: A randomised, placebo‐controlled trial
Lisdexamfetamine in the treatment of methamphetamine dependence: A randomised, placebo‐controlled trial Open
Aims This study tested the efficacy and safety of a 12‐week course of lisdexamfetamine in reducing methamphetamine use, an outcome which is associated with improvements in health and wellbeing, in people dependent on methamphetamine. Desig…
View article: Reducing Methamphetamine Use in Aboriginal and Torres Strait Islander Communities With the “We Can Do This” Web App: Qualitative Evaluation of Acceptability and Feasibility
Reducing Methamphetamine Use in Aboriginal and Torres Strait Islander Communities With the “We Can Do This” Web App: Qualitative Evaluation of Acceptability and Feasibility Open
Background Preventing and treating methamphetamine-related harm in Aboriginal and Torres Strait Islander populations is a significant challenge for health care services. Digital health care may offer opportunities to support individuals an…
View article: Implementation of time-limited parenteral hydromorphone in people with treatment-resistant injecting opioid use disorder: a protocol for a single-site, uncontrolled, open-label study to assess feasibility, safety and cost
Implementation of time-limited parenteral hydromorphone in people with treatment-resistant injecting opioid use disorder: a protocol for a single-site, uncontrolled, open-label study to assess feasibility, safety and cost Open
Introduction Supervised injectable opioid treatment (SIOT) is an evidence-based intervention targeting opioid-dependent people for whom existing treatments have been ineffective. This project will primarily assess the feasibility and the a…
View article: ‘You mean you're not doing it already?’ A national sentinel toxico‐surveillance system for detecting illicit, emerging and novel psychoactive drugs in presentations to emergency departments
‘You mean you're not doing it already?’ A national sentinel toxico‐surveillance system for detecting illicit, emerging and novel psychoactive drugs in presentations to emergency departments Open
Patients presenting to the ED after using illicit drugs, including novel psychoactive substances, are a unique source of information on substances that are directly causing acute harm in the community. Conventionally, illicit drug intoxica…
View article: Effect of a Smartphone App (S-Check) on Actual and Intended Help-Seeking and Motivation to Change Methamphetamine Use Among Adult Consumers of Methamphetamine in Australia: Randomized Waitlist-Controlled Trial
Effect of a Smartphone App (S-Check) on Actual and Intended Help-Seeking and Motivation to Change Methamphetamine Use Among Adult Consumers of Methamphetamine in Australia: Randomized Waitlist-Controlled Trial Open
Background Interventions are required that address delays in treatment-seeking and low treatment coverage among people consuming methamphetamine. Objective We aim to determine whether a self-administered smartphone-based intervention, the …
View article: HARMONY (HARM reduction for Opiates, Nicotine and You) Trial: Protocol of a Randomised Controlled Trial of the Effectiveness of Vaporised Nicotine Products for Tobacco Smoking Cessation amongst NSW Opiate Agonist Treatment Clients
HARMONY (HARM reduction for Opiates, Nicotine and You) Trial: Protocol of a Randomised Controlled Trial of the Effectiveness of Vaporised Nicotine Products for Tobacco Smoking Cessation amongst NSW Opiate Agonist Treatment Clients Open
Introduction Tobacco smoking is a major cause of preventable disease in Australia. Individuals receiving opiate agonist treatment (OAT) are a group who experience high tobacco-related morbidity and mortality rates. Despite reporting a desi…
View article: HARMONY (HARM reduction for Opiates, Nicotine and You): Statistical Analysis Plan for a Randomised Controlled Trial of the Effectiveness of Vaporised Nicotine Products for Tobacco Smoking Cessation amongst NSW Opiate Agonist Treatment Clients
HARMONY (HARM reduction for Opiates, Nicotine and You): Statistical Analysis Plan for a Randomised Controlled Trial of the Effectiveness of Vaporised Nicotine Products for Tobacco Smoking Cessation amongst NSW Opiate Agonist Treatment Clients Open
Background The HARMONY study is a multicentre, randomised, single-blinded parallel group trial. It will compare the effectiveness of a 12-week course of liquid nicotine delivered via vapourised nicotine products (VNPs) to best practice nic…
View article: Web-Based Application for Reducing Methamphetamine Use Among Aboriginal and Torres Strait Islander People: Randomized Waitlist Controlled Trial
Web-Based Application for Reducing Methamphetamine Use Among Aboriginal and Torres Strait Islander People: Randomized Waitlist Controlled Trial Open
Background Digital interventions can help to overcome barriers to care, including stigma, geographical distance, and a lack of culturally appropriate treatment options. “We Can Do This” is a web-based app that was designed with input from …
View article: Trends in reported <scp>GHB</scp>‐related presentations to Sydney emergency departments between 2012 and 2021
Trends in reported <span>GHB</span>‐related presentations to Sydney emergency departments between 2012 and 2021 Open
Objectives In overdose, gamma‐hydroxybutyrate (GHB) and its precursors can cause decreased levels of consciousness, coma and death. Here, we aim to describe reported exposure to GHB at four EDs in Sydney, New South Wales (NSW), Australia. …
View article: Participant experiences in a pilot study for methamphetamine withdrawal treatment: Implications for retention
Participant experiences in a pilot study for methamphetamine withdrawal treatment: Implications for retention Open
The experiences of participants in this clinical trial can be distilled into four meta-themes: agency, caring-trust, safety, and communication. Participants spontaneously linked these experiences with a capacity to remain enrolled in the s…
View article: A multicentre case series of analytically confirmed gamma‐hydroxybutyrate intoxications in Western Australian emergency departments: Pre‐hospital circumstances, co‐detections and clinical outcomes
A multicentre case series of analytically confirmed gamma‐hydroxybutyrate intoxications in Western Australian emergency departments: Pre‐hospital circumstances, co‐detections and clinical outcomes Open
Introduction Gamma‐hydroxybutyrate (GHB) use is associated with high risk of accidental overdose. This study examined the pre‐hospital circumstances, demographic characteristics and clinical outcomes of analytically confirmed GHB emergency…
View article: Measuring Objective and Subjective Sleep during Lisdexamfetamine Treatment of Acute Methamphetamine Withdrawal: A Feasibility Study
Measuring Objective and Subjective Sleep during Lisdexamfetamine Treatment of Acute Methamphetamine Withdrawal: A Feasibility Study Open
Introduction: Sleep disturbance is common during methamphetamine (MA) use and withdrawal; however, the feasibility of combined subjective-objective measurement of sleep-wake has not been shown in this population. Actigraphy i…