Nadir M. Balba
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View article: The potential role of chronic pain and the polytrauma clinical triad in predicting prodromal PD: A cross-sectional study of U.S. Veterans
The potential role of chronic pain and the polytrauma clinical triad in predicting prodromal PD: A cross-sectional study of U.S. Veterans Open
These data demonstrate the potential utility of chronic pain, TBI, and PTSD in the prediction of pPD, and the importance of trauma-related factors in the pathogenesis of PD.
View article: 0270 EEG Slow Wave Coherence is Related to PSG-Derived Measures of Sleep Fragmentation and Cognition in the WashU BASE Cohort
0270 EEG Slow Wave Coherence is Related to PSG-Derived Measures of Sleep Fragmentation and Cognition in the WashU BASE Cohort Open
Introduction There exists a bidirectional relationship between sleep disruption and neuropathology in Alzheimer’s disease (AD). Electroencephalogram (EEG) during polysomnography (PSG) provides an opportunity to examine stereotyped, coordin…
View article: 0271 Actigraphy Based Measures of Sleep Disruption and Circadian Rhythms in the WashU Biomarkers of Alzheimer’s Disease in Sleep and EEG (BASE) Cohort
0271 Actigraphy Based Measures of Sleep Disruption and Circadian Rhythms in the WashU Biomarkers of Alzheimer’s Disease in Sleep and EEG (BASE) Cohort Open
Introduction Prospective studies of Alzheimer’s disease (AD) demonstrate sleep-wake disturbances may precede and accelerate with cognitive decline. Use of wrist-actigraphy in conjunction with overnight polysomnography (PSG) enables researc…
View article: Feasibility and preliminary efficacy for morning bright light therapy to improve sleep and plasma biomarkers in US Veterans with TBI. A prospective, open-label, single-arm trial
Feasibility and preliminary efficacy for morning bright light therapy to improve sleep and plasma biomarkers in US Veterans with TBI. A prospective, open-label, single-arm trial Open
Mild traumatic brain injury (TBI) is associated with persistent sleep-wake dysfunction, including insomnia and circadian rhythm disruption, which can exacerbate functional outcomes including mood, pain, and quality of life. Present therapi…
View article: Photosensitivity Is Associated with Chronic Pain following Traumatic Brain Injury
Photosensitivity Is Associated with Chronic Pain following Traumatic Brain Injury Open
Individuals with a history of traumatic brain injury (TBI) report increased rates of chronic pain. Photosensitivity is also a common chronic symptom following TBI and is prevalent among other types of chronic pain. The aim of this study wa…
View article: Different Methods for Traumatic Brain Injury Diagnosis Influence Presence and Symptoms of Post-Concussive Syndrome in United States Veterans
Different Methods for Traumatic Brain Injury Diagnosis Influence Presence and Symptoms of Post-Concussive Syndrome in United States Veterans Open
Common methods for evaluating history of traumatic brain injury (TBI) include self-report, electronic medical record review (EMR), and structured interviews such as the Head Trauma Events Characteristics (HTEC). Each has strengths and weak…
View article: 799 Automated Detection of Slow Wave Coherence in Sleep EEG: A potential neurophysiological correlate of cognitive decline
799 Automated Detection of Slow Wave Coherence in Sleep EEG: A potential neurophysiological correlate of cognitive decline Open
Introduction A bidirectional relationship exists between sleep disruption and neuropathology in Alzheimer’s disease (AD). The sleep electroencephalogram (EEG) is a highly stereotyped, direct neurophysiological window into brain function; p…
View article: 069 Chronic pain in Veterans with TBI is associated with decreased EEG slow wave coherence during NREM sleep
069 Chronic pain in Veterans with TBI is associated with decreased EEG slow wave coherence during NREM sleep Open
Introduction Chronic pain and sleep disturbances are intricately linked to one another, especially in individuals with a history of traumatic brain injury (TBI) who are at greater risk for both symptoms. Although prior studies have analyze…
View article: 277 Tunable White Light for Elders (TWLITE): A feasibility study of a home-based sleep intervention
277 Tunable White Light for Elders (TWLITE): A feasibility study of a home-based sleep intervention Open
Introduction Sleep disturbances are common in elderly patients and may contribute to disease progression in certain populations (e.g., Alzheimer’s Disease). Light therapy is a simple and cost-effective intervention to improve sleep. Primar…
View article: 0869 Morning Bright Light Improves Insomnia, Mood, And Pain In Veterans With TBI And PTSD
0869 Morning Bright Light Improves Insomnia, Mood, And Pain In Veterans With TBI And PTSD Open
Insomnia is common among Veterans with Traumatic Brain Injury (TBI) and Posttraumatic Stress Disorder (PTSD). This study sought to determine the effect of morning bright light therapy (MBLT) on sleep, mood, pain, and other quality of life …
View article: Increased Sleep Disturbances and Pain in Veterans With Comorbid Traumatic Brain Injury and Posttraumatic Stress Disorder
Increased Sleep Disturbances and Pain in Veterans With Comorbid Traumatic Brain Injury and Posttraumatic Stress Disorder Open
These data suggest sleep and pain are worst in Veterans with TBI and PTSD, and that sleep is similarly impaired in Veterans with PTSD despite not having as much pain. Thus, although this is a complex relationship, these data suggest PTSD m…
View article: Trauma-Associated Sleep Disturbances: a Distinct Sleep Disorder?
Trauma-Associated Sleep Disturbances: a Distinct Sleep Disorder? Open