Nagwa A. Sabri
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View article: Authors reply: “The clinical outcome of Montelukast versus co-enzyme Q10 in adult patients with sepsis: A randomized controlled clinical trial”
Authors reply: “The clinical outcome of Montelukast versus co-enzyme Q10 in adult patients with sepsis: A randomized controlled clinical trial” Open
View article: Impact of vitamin D3 intake on hemoglobin levels and erythropoietin response in patients on hemodialysis: a randomized single blinded trial
Impact of vitamin D3 intake on hemoglobin levels and erythropoietin response in patients on hemodialysis: a randomized single blinded trial Open
Purpose Patients on regular hemodialysis (HD) are at the highest risk of developing anemia. Vitamin D deficiency is more prevalent in HD patients. Recent studies have suggested that improving vitamin D status can reduce both anemia and the…
View article: New insights into pentoxifylline and α-lipoic acid: Co-administration with clomiphene citrate for ovulation induction in anovulatory women with polycystic ovary syndrome
New insights into pentoxifylline and α-lipoic acid: Co-administration with clomiphene citrate for ovulation induction in anovulatory women with polycystic ovary syndrome Open
Objective: This study investigated the effects of pentoxifylline (PTX) and α-lipoic acid (ALA) on ovulation and pregnancy rates in women with clomiphene citrate (CC) resistant polycystic ovary syndrome (PCOS).Methods: A prospective, random…
View article: Issues and Challenges of Building Information Modelling (BIM) Implementation in Facilities Management
Issues and Challenges of Building Information Modelling (BIM) Implementation in Facilities Management Open
Building Information Modelling (BIM) is one of the industry's emerging construction technologies. However, BIM adoption for Facilities Management (FM) has not yet been acknowledged. Traditional processes continue to drive FM in Malaysia, s…
View article: Clinical pharmacist-led anticoagulation stewardship program: improve physician adherence to evidence-based guidelines and reduce anticoagulant-related medication errors
Clinical pharmacist-led anticoagulation stewardship program: improve physician adherence to evidence-based guidelines and reduce anticoagulant-related medication errors Open
Background Due to their high risk of medication errors (MEs) and the potentially devastating thrombotic and bleeding events, anticoagulants are a class of high-risk medications that require regular monitoring by healthcare professionals. T…
View article: Melatonin ameliorates inflammation and improves outcomes of ischemia/reperfusion injury in patients undergoing coronary artery bypass grafting surgery: a randomized placebo-controlled study
Melatonin ameliorates inflammation and improves outcomes of ischemia/reperfusion injury in patients undergoing coronary artery bypass grafting surgery: a randomized placebo-controlled study Open
To investigate the protective role of high dose melatonin concerning myocardial I/R injury and inflammation in patients undergoing on-pump coronary artery bypass grafting (CABG) surgery by evaluating IR/inflammatory biomarkers and clinical…
View article: The Reno-protective effect of SGLT-2 inhibitors in non-diabetic patients. A comparative review
The Reno-protective effect of SGLT-2 inhibitors in non-diabetic patients. A comparative review Open
View article: Association between UGT2B7 Genetic Polymorphism and Pharmacokinetics of Empagliflozin in Humans
Association between UGT2B7 Genetic Polymorphism and Pharmacokinetics of Empagliflozin in Humans Open
View article: Relation between blood disorders in pregnancy and both mother and fetal health status
Relation between blood disorders in pregnancy and both mother and fetal health status Open
View article: Evaluation of the efficacy of triazavirin versus oseltamivir in management of COVID-19
Evaluation of the efficacy of triazavirin versus oseltamivir in management of COVID-19 Open
Aim: To compare the safety and efficacy of triazavirin (TZV) 250 mg capsules versus oseltamivir 75 mg capsules in the treatment of individuals diagnosed with COVID-19.Materials & methods: A double-blind, randomized, intervent…
View article: Evaluation of the effect of pentoxifylline on the prevention of paclitaxel‑induced peripheral neuropathy in breast cancer patients: a randomized controlled study
Evaluation of the effect of pentoxifylline on the prevention of paclitaxel‑induced peripheral neuropathy in breast cancer patients: a randomized controlled study Open
Background Paclitaxel-induced peripheral neuropathy (PIPN) is one of the most common and debilitating toxicity. Up till now, no treatment or preventive medication is recommended by guidelines. Pentoxifylline has been found to prevent PIPN …
View article: Cholecalciferol effect on oxidative stress and novel predictors of inflammation in hemodialysis patients: a prospective randomized trial
Cholecalciferol effect on oxidative stress and novel predictors of inflammation in hemodialysis patients: a prospective randomized trial Open
Background Emerging evidence links vitamin D deficiency to oxidative stress (OS) and inflammation, posing ongoing risks to cardiovascular outcomes in hemodialysis (HD) patients. Despite this, current data are lacking regarding the optimal …
View article: New incidence or recurrence hepatocellular carcinoma (HCC) in genotype 4 hepatitis C virus treated with sofosbuvir/daclatasvir with or without ribavirin
New incidence or recurrence hepatocellular carcinoma (HCC) in genotype 4 hepatitis C virus treated with sofosbuvir/daclatasvir with or without ribavirin Open
Background: Several studies have resulted in controversial data about the recurrence or new incidence of hepatocellular carcinoma (HCC) in patients with hepatitis C who were treated with direct-acting antivirals (DAAs). Aim: This observati…
View article: Evaluation of the Effect of Loratadine versus Diosmin/Hesperidin Combination on Vinca Alkaloids-Induced Neuropathy: A Randomized Controlled Clinical Trial
Evaluation of the Effect of Loratadine versus Diosmin/Hesperidin Combination on Vinca Alkaloids-Induced Neuropathy: A Randomized Controlled Clinical Trial Open
Neurological injury is a crucial problem that interferes with the therapeutic use of vinca alkaloids as well as the quality of patient life. This study was conducted to assess the impact of using loratadine or diosmin/hesperidin on neuropa…
View article: Different Therapeutic Modalities for management of COVID-19
Different Therapeutic Modalities for management of COVID-19 Open
There is a global health concern caused by the COVID-19 pandemic and need for effective treatments to reduce morbidity and mortality associated with the disease.Aim: The review aims to highlight and compare between different therapeutic mo…
View article: Effect of pentoxifylline on endothelial dysfunction, oxidative stress and inflammatory markers in STEMI patients
Effect of pentoxifylline on endothelial dysfunction, oxidative stress and inflammatory markers in STEMI patients Open
Aim: ST-elevation myocardial infarction (STEMI) patients suffer higher mortality and adverse outcomes linked to endothelial dysfunction (ED). Methods: 43 patients were randomized to pentoxifylline (PTX) 400 mg thrice daily (n…
View article: Different modalities to manage rheumatoid arthritis: an A to Z story
Different modalities to manage rheumatoid arthritis: an A to Z story Open
Aim: To investigate different approaches to RA treatment that might lead to greater efficacy and better safety profiles. Methods: The Search strategy was based on medical subject headings, and screening and selection were based on inclusio…
View article: The Association between ATP-Binding Cassette C2 (ABCC2) Transporter Genetic Polymorphism and Peripheral Neuropathy in Gastrointestinal Cancer Patients Receiving Oxaliplatin.
The Association between ATP-Binding Cassette C2 (ABCC2) Transporter Genetic Polymorphism and Peripheral Neuropathy in Gastrointestinal Cancer Patients Receiving Oxaliplatin. Open
Introduction: Single nucleotide polymorphisms (SNPs) in ATP-binding cassette C2 (ABCC2) gene may lead to higher intracellular oxaliplatin accumulation in the dorsal root ganglia and thus increased risk of oxaliplatin-induced peripheral neu…
View article: Retraction Note: Effects of genistein on pentylenetetrazole-induced behavioral and neurochemical deficits in ovariectomized rats
Retraction Note: Effects of genistein on pentylenetetrazole-induced behavioral and neurochemical deficits in ovariectomized rats Open
View article: Immunomodulatory and Antioxidant Effects of Pentoxifylline and Other Therapeutic Agents in The Management of Myocardial Injury
Immunomodulatory and Antioxidant Effects of Pentoxifylline and Other Therapeutic Agents in The Management of Myocardial Injury Open
Myocardial injury, particularly during myocardial infarction (MI), triggers an inflammatory response that is crucial for starting the myocardial healing process but is also responsible for cardiac remodeling and heart failure that can deve…
View article: β1-Adrenergic Receptor Polymorphisms: A Possible Genetic Predictor of Bisoprolol Response in Acute Coronary Syndrome
β1-Adrenergic Receptor Polymorphisms: A Possible Genetic Predictor of Bisoprolol Response in Acute Coronary Syndrome Open
Arg389Gly polymorphism is a promising bisoprolol response predictor in ACS patients.
View article: Associations between Nutrigenomic Effects and Incidences of Microbial Resistance against Novel Antibiotics
Associations between Nutrigenomic Effects and Incidences of Microbial Resistance against Novel Antibiotics Open
Nutrigenomics is the study of the impact of diets or nutrients on gene expression and phenotypes using high-throughput technologies such as transcriptomics, proteomics, metabolomics, etc. The bioactive components of diets and nutrients, as…
View article: Advances in the Applications of Bioinformatics and Chemoinformatics
Advances in the Applications of Bioinformatics and Chemoinformatics Open
Chemoinformatics involves integrating the principles of physical chemistry with computer-based and information science methodologies, commonly referred to as “in silico techniques”, in order to address a wide range of descriptive and presc…
View article: Assessment of barriers to optimum enteral nutrition practices as perceived by critical care providers
Assessment of barriers to optimum enteral nutrition practices as perceived by critical care providers Open
Background Nutritional support is a vital intervention for critically ill patients. Despite the existence of several clinical practice guidelines focused on enteral nutrition of critically ill, there is still a gap between guideline recomm…
View article: #3706 EFFECT OF CHOLECALCIFEROL INTAKE ON NOVEL INFLAMMATORY INDICATORS IN HEMODIALYSIS PATIENTS
#3706 EFFECT OF CHOLECALCIFEROL INTAKE ON NOVEL INFLAMMATORY INDICATORS IN HEMODIALYSIS PATIENTS Open
Background and Aims Hemodialysis patients (HD) are in a chronic state of systemic inflammation, with vast majority of these patients are vitamin D deficient. Vitamin D appears to be a strong controller of inflammation. It's well known that…
View article: Evaluation of the Safety Profile of Direct-Acting Antivirals on Patients with Hepatitis C Virus: A Pharmacovigilance Study
Evaluation of the Safety Profile of Direct-Acting Antivirals on Patients with Hepatitis C Virus: A Pharmacovigilance Study Open
Background Hepatitis C virus (HCV) is the primary contributor to chronic hepatic diseases. A rapid change in the situation took place with the advent of oral direct-acting antivirals (DAAs). However, a comprehensive review of the adverse e…
View article: Association between Food/UGT2B7 Polymorphisms and Pharmacokinetics/Pharmacodynamics Properties of Indapamide in Healthy Humans
Association between Food/UGT2B7 Polymorphisms and Pharmacokinetics/Pharmacodynamics Properties of Indapamide in Healthy Humans Open
Indapamide is an effective and safe antihypertensive medication showing a beneficial effect in combination with other antihypertensive agents regarding morbidity and mortality. A comparative study was performed under fasting and fed condit…
View article: Association between Nutrigenomics and Incidence of Microbial Resistant Strains against Novel Antibiotics
Association between Nutrigenomics and Incidence of Microbial Resistant Strains against Novel Antibiotics Open
Nutrigenomics is the study of the interaction of nutrition and genes, focusing on the influence of nutrients on the genome, proteome, and metabolome, and how nutrition affects human health. In the context of nutrigenomics, bioactive compon…
View article: Chemoinformatics Advances from Egypt: A Review Article
Chemoinformatics Advances from Egypt: A Review Article Open
Chemoinformatics is the combination of physical chemistry theory with computer and information science techniques "in silico techniques" to a variety of descriptive and prescriptive chemistry issues, including applications to bio…
View article: Assessment of neonatal intensive care unit nurses’ compliance with standard precautions of infection control and identification of enabling factors
Assessment of neonatal intensive care unit nurses’ compliance with standard precautions of infection control and identification of enabling factors Open
Background Rigorous implementation of infection prevention and control practices by healthcare workers in different healthcare settings is of utmost importance. Neonates, particularly preterm babies in neonatal intensive care units, are a …