Nahed Soliman
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View article: Downregulation of lncRNA-MALAT1, Altered Immunohistochemical Expression of Cyclin D1 Protein and E-Cadherin Protein in Correlation to Meningioma Grades
Downregulation of lncRNA-MALAT1, Altered Immunohistochemical Expression of Cyclin D1 Protein and E-Cadherin Protein in Correlation to Meningioma Grades Open
lncRNA MALAT1 is downregulated in meningiomas and associated with increased aggressiveness. Overexpressed cyclin D1 and decreased E-cadherin expression are also associated with high grade meningioma.
View article: Inverse correlation of concurrent BCL2, and C MYC expressions and CD30 positivity as regard the Prognostic significance in diffuse large B-cell lymphoma
Inverse correlation of concurrent BCL2, and C MYC expressions and CD30 positivity as regard the Prognostic significance in diffuse large B-cell lymphoma Open
Background : C MYC, BCL2 and CD30 play an important role in initiation and propagation of diffuse large B-cell lymphoma (DLBCL).Protein expression of these marker were used in the diagnosis, predicting the prognosis and as a therapeutic ta…
View article: Salbutamol and Epinephrine Inhalation as a Conservative Treatment of Transient Tachypnea of Newborn: a Pilot Randomized Controlled Trial
Salbutamol and Epinephrine Inhalation as a Conservative Treatment of Transient Tachypnea of Newborn: a Pilot Randomized Controlled Trial Open
Objective: To evaluate the efficacy and the safety of inhaled salbutamol and epinephrine in the treatment of TTN. Design: Double-blinded randomized control pilot study was carried out on 135 near and full-term infants with TTN in the NICU …
View article: Prognostic Value of BRAF, Programmed Cell Death 1 (PD1), and PD Ligand 1 (PDL1) Protein Expression in Colon Adenocarcinoma
Prognostic Value of BRAF, Programmed Cell Death 1 (PD1), and PD Ligand 1 (PDL1) Protein Expression in Colon Adenocarcinoma Open
Patients with colorectal cancer in different stages show variable outcomes/therapeutic responses due to their distinct tumoral biomarkers and biological features. In this sense, this study aimed to explore the prognostic utility of BRAF, p…
View article: The Impact of Tumor Infiltrating Lymphocytes Densities and Ki67 Index on Residual Breast Cancer Burden following Neoadjuvant Chemotherapy
The Impact of Tumor Infiltrating Lymphocytes Densities and Ki67 Index on Residual Breast Cancer Burden following Neoadjuvant Chemotherapy Open
To avoid unnecessary neoadjuvant chemotherapy in case anticipating a poor therapy response, it is essential to find the pathological parameters that would predict pathological complete response or at least a decrease in tumor burden follow…
View article: Notch1-Jagged1 Signaling Pathway in Oral Squamous Cell Carcinoma: Relation to Tumor Recurrence and Patient Survival
Notch1-Jagged1 Signaling Pathway in Oral Squamous Cell Carcinoma: Relation to Tumor Recurrence and Patient Survival Open
BACKGROUND: Dysregulated Jagged1/Notch1 signaling has been implicated in a variety of carcinomas, but little is known about the expression and possible role of Jagged1 and Notch1 in patients with oral squamous cell carcinoma (OSCC). AIM: W…
View article: Immunohistochemical Expression of SATB2 and Clinicopathological Correlation in Colorectal Adenocarcinoma
Immunohistochemical Expression of SATB2 and Clinicopathological Correlation in Colorectal Adenocarcinoma Open
Special AT-rich sequence-binding protein 2(SATB2) is a peculiar marker in the diagnosis of colorectal carcinoma (CRC), SATB2 has been employed as a colorectal differentiation marker with the potential to be useful in distinguishing the ori…
View article: Histopathological impact of Ginger loaded nanoparticle versus ginger extract as a novel therapy of experimentally induced acute ulcerative colitis
Histopathological impact of Ginger loaded nanoparticle versus ginger extract as a novel therapy of experimentally induced acute ulcerative colitis Open
Background: Ulcerative colitis (UC) is a debilitating chronic inflammatory bowel disease that is prevalent in Egypt. Current treatment of UC is expensive and has serious side effects. Aim of the Work: To evaluate the effect of ginger loade…
View article: Immunohistochemical Expression of MMR Proteins with Clinicopathological Correlation in Colorectal Cancer in Egypt
Immunohistochemical Expression of MMR Proteins with Clinicopathological Correlation in Colorectal Cancer in Egypt Open
BACKGROUND: Microsatellite instability (MSI) is the genetic pathway underlying 15% of sporadic colorectal carcinoma (CRC) and hereditary non-polyposis CRC. MSI-H CRC has a distinct clinicopathological characteristic including excess mucin …
View article: Ki-67 as a prognostic marker according to breast cancer molecular subtype
Ki-67 as a prognostic marker according to breast cancer molecular subtype Open
Ki-67 may be considered as a valuable biomarker in breast cancer patients.