Gwang Ha Kim
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View article: Fexuprazan for the Prevention of Nonsteroidal Anti-Inflammatory Drug-Induced Peptic Ulcer: A New Player in the Gastroprotection Landscape
Fexuprazan for the Prevention of Nonsteroidal Anti-Inflammatory Drug-Induced Peptic Ulcer: A New Player in the Gastroprotection Landscape Open
Background/Aims: Current guidelines recommend biannual ultrasound for hepatocellular carcinoma (HCC) surveillance in chronic hepatitis B (CHB) patients. However, computed tomography (CT) or magnetic resonance imaging (MRI) may be used when…
View article: Natural History of Gastric Subepithelial Tumors: Long-Term Outcomes and Surveillance Strategies
Natural History of Gastric Subepithelial Tumors: Long-Term Outcomes and Surveillance Strategies Open
Gastric subepithelial tumors (SETs) are commonly identified during routine endoscopy. Most SETs are asymptomatic and small (<2 cm) and exhibit benign behavior over time. Various histopathological types exist, including benign lesions, such…
View article: The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study
The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study Open
Background In Korea, the National Cancer Screening Program (NCSP) was implemented in 1999 and provides biennial endoscopy for adults aged ≥40 years. The NCSP has contributed to the early detection of gastric cancer and reduction of associa…
View article: Comparative Efficacy of Potassium-Competitive Acid Blocker-Based Triple Therapy with Tegoprazan versus Vonoprazan for <i>Helicobacter pylori</i> Eradication: A Randomized, Double-Blind, Active-Controlled Pilot Study
Comparative Efficacy of Potassium-Competitive Acid Blocker-Based Triple Therapy with Tegoprazan versus Vonoprazan for <i>Helicobacter pylori</i> Eradication: A Randomized, Double-Blind, Active-Controlled Pilot Study Open
After 10 days, tegoprazan 100 mg showed eradication rates comparable to those of vonoprazan 20 mg, while 50 mg may be insufficient. These findings support future research to optimize tegoprazan dosing in clinical practice (ClinicalTrials.g…
View article: Recent advancement in size measurement during endoscopy
Recent advancement in size measurement during endoscopy Open
Accurate lesion size measurement is essential in endoscopic practice as it influences treatment strategies, surveillance decisions, and clinical outcomes, especially in colorectal polyps. Traditional measurement techniques, including visua…
View article: Navigating the Treatment Landscape for Widespread Superficial Esophageal Squamous Cell Neoplasia
Navigating the Treatment Landscape for Widespread Superficial Esophageal Squamous Cell Neoplasia Open
Background/Aims: The prognostic value of serial 18F-fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) for patients with borderline resectable or locally advanced pancreatic cancer who undergo conversion …
View article: Korean Registry on the Current Management of <i>Helicobacter pylori</i> (K-Hp-Reg): Interim Analysis of Adherence to the Revised Evidence-Based Guidelines for First-Line Treatment
Korean Registry on the Current Management of <i>Helicobacter pylori</i> (K-Hp-Reg): Interim Analysis of Adherence to the Revised Evidence-Based Guidelines for First-Line Treatment Open
The revised guidelines for the treatment of H. pylori infection have been increasingly adopted in routine clinical practice in Korea, which may have contributed to improved first-line eradication rates. Notably, the 14-day CTT, 10-day CT, …
View article: Evaluation of the Efficacy and Safety of a Dual Delayed-Release Formulation of 10-mg Esomeprazole in Patients with Gastric Erosions: A Multicenter, Randomized, Double-Blind, Active-Control, Phase III Study
Evaluation of the Efficacy and Safety of a Dual Delayed-Release Formulation of 10-mg Esomeprazole in Patients with Gastric Erosions: A Multicenter, Randomized, Double-Blind, Active-Control, Phase III Study Open
The efficacy and safety of HIP2101 were comparable to those of RLD2101 in the treatment of gastric erosions and symptomatic improvement. These findings suggest that HIP2101 may be a novel treatment option for gastritis (ClinicalTrials.gov …
View article: The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study (Preprint)
The Cost-Effectiveness of Adding Helicobacter Pylori Screening to the National Gastric Cancer Screening Program in Korea: Protocol for a Cost-Effectiveness Modeling Study (Preprint) Open
BACKGROUND In Korea, the National Cancer Screening Program (NCSP) was implemented in 1999 and provides biennial endoscopy for adults aged ≥40 years. The NCSP has contributed to the early detection of gastric cancer and reduction of associ…
View article: Anti-inflammatory effects of eupatilin on Helicobacter pylori CagA-induced gastric inflammation
Anti-inflammatory effects of eupatilin on Helicobacter pylori CagA-induced gastric inflammation Open
Background Eupatilin, a flavone isolated from Artemisia species, exerts anti-inflammatory, anti-oxidative, and anti-neoplastic activities. However, the effects of eupatilin on H . pylori -associated gastritis remain unclear. Thus, this stu…
View article: Correlation between White Globe Appearance and Clinicopathologic Characteristics in Early Gastric Cancer
Correlation between White Globe Appearance and Clinicopathologic Characteristics in Early Gastric Cancer Open
WGA was associated with small tumor size, differentiated-type histology, and middle-third tumor location, and was more frequently observed in lesions with an oval/tubular MS and fine-network MV patterns and the absence of WOS.
View article: Endoscopic Resection for Superficial Non-Ampullary Duodenal Epithelial Tumors
Endoscopic Resection for Superficial Non-Ampullary Duodenal Epithelial Tumors Open
An increasing number of superficial non-ampullary duodenal epithelial tumors (SNADETs) have been detected recently owing to the development of endoscopic imaging technology and increased awareness of this disease. Endoscopic resection is t…
View article: Clinical Implications of Circulating Tumor Cells in Patients with Esophageal Squamous Cell Carcinoma: Cancer-Draining Blood Versus Peripheral Blood
Clinical Implications of Circulating Tumor Cells in Patients with Esophageal Squamous Cell Carcinoma: Cancer-Draining Blood Versus Peripheral Blood Open
Circulating tumor cells (CTCs) in cancer-draining veins have diagnostic and prognostic value. However, studies on esophageal squamous cell carcinoma (ESCC) are limited. This study aimed to compare CTCs obtained from different sampling site…
View article: Optimal Surveillance of Metachronous Gastric Lesion after Endoscopic Resection of Early Gastric Cancer
Optimal Surveillance of Metachronous Gastric Lesion after Endoscopic Resection of Early Gastric Cancer Open
Endoscopic resection (ER)-a minimal invasive procedure, compared to surgical gastrectomy, with the advantage of preserving the entire stomach and maintaining the patient's quality of life-is a widely used curative treatment for early gastr…
View article: Empirical Therapy Versus Tailored Therapy of <i>Helicobacter pylori</i> in Korea: Results of the K‐<scp>CREATE</scp> Study
Empirical Therapy Versus Tailored Therapy of <i>Helicobacter pylori</i> in Korea: Results of the K‐<span>CREATE</span> Study Open
Background The optimal duration of regimens for tailored therapy based on genotypic resistance for clarithromycin has yet to be established. Aim This study was a nationwide, multicenter, randomized trial comparing empirical therapy with ta…
View article: Efficacy of fexuprazan compared with rebamipide in Korean patients with gastritis: A matching-adjusted indirect comparison
Efficacy of fexuprazan compared with rebamipide in Korean patients with gastritis: A matching-adjusted indirect comparison Open
BACKGROUND Gastritis is one of the most frequently diagnosed diseases requiring medical treatment in South Korea. Fexuprazan, a novel potassium-competitive acid blocker, has been approved for treating gastritis and erosive esophagitis. Mea…
View article: Endoscopic treatment of a large Brunner’s gland hamartoma in the duodenum
Endoscopic treatment of a large Brunner’s gland hamartoma in the duodenum Open
A 62-year-old woman visited our hospital for further evaluation of a large elongated polypoid mass in the duodenum, which was incidentally discovered during a health check-up endoscopy. The patient had a medical history of hypertension and…
View article: Artificial Intelligence-Based Diagnosis of Gastric Mesenchymal Tumors Using Digital Endosonography Image Analysis
Artificial Intelligence-Based Diagnosis of Gastric Mesenchymal Tumors Using Digital Endosonography Image Analysis Open
Background/Objectives: Artificial intelligence (AI)-assisted endoscopic ultrasonography (EUS) diagnostic tools have shown excellent performance in diagnosing gastric mesenchymal tumors. This study aimed to assess whether incorporating clin…
View article: Effective Endoscopic Submucosal Dissection of a Huge Esophageal Liposarcoma: A Case Report
Effective Endoscopic Submucosal Dissection of a Huge Esophageal Liposarcoma: A Case Report Open
This case report presents the successful endoscopic submucosal dissection (ESD) of a well-differentiated esophageal liposarcoma in a 51-year-old male with persistent dysphagia. The cause was initially diagnosed as a 10 cm pedunculated lesi…
View article: A rare case of esophageal mucoepidermoid carcinoma successfully treated via endoscopic submucosal dissection
A rare case of esophageal mucoepidermoid carcinoma successfully treated via endoscopic submucosal dissection Open
Esophageal mucoepidermoid carcinoma (EMEC) is a special subtype of esophageal malignancy, accounting for less than 1% of all cases of primary esophageal carcinoma. Pathologically, it consists of a mixture of adenocarcinoma and squamous cel…