Nancy Amin
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View article: An endothelial cell competition assay for determinants of the response to targeted anti-angiogenics
An endothelial cell competition assay for determinants of the response to targeted anti-angiogenics Open
/SUMMARYAnti-angiogenics, inhibitors of pathological blood vessel growth, are an important class of targeted agent for the treatment of common cancers and ocular conditions. However, efficacy is compromised by the absence of biomarkers to …
View article: The Impact of BRCA1 Expression on Survival Status in Ovarian Serous Carcinoma of Egyptian Patients
The Impact of BRCA1 Expression on Survival Status in Ovarian Serous Carcinoma of Egyptian Patients Open
Positive BRCA1 expression had proven to be associated with advanced stage & grade of tumors, as well as worsened prognostic survival parameters (metastasis, recurrence, residual disease, and mortality) in patients with ovarian serous carci…
View article: Expression of PD-L1 in Early-Stage Invasive Breast Carcinoma and Its Relation to Tumor-Infiltrating Lymphocytes
Expression of PD-L1 in Early-Stage Invasive Breast Carcinoma and Its Relation to Tumor-Infiltrating Lymphocytes Open
Although the impact of PD-L1 on early-stage BC outcomes had not been clearly established, our results indicated that PD-L1 is a negative prognostic marker in early settings. PD-L1 can serve as a new therapeutic target for patients with hig…
View article: Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells
Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells Open
Background: Metastasis underlies most colorectal cancer mortality. Cancer cells spread through the body as single cells or small clusters of cells that have an invasive, mesenchymal, nonproliferative phenotype. At the secondary site, they …