Baohua Yu
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View article: Advances in research on biomarkers of immune checkpoint inhibitor-related pneumonitis in non-small cell lung cancer
Advances in research on biomarkers of immune checkpoint inhibitor-related pneumonitis in non-small cell lung cancer Open
Lung cancer, primarily non-small cell lung cancer (NSCLC), is a major factor affecting cancer-associated deaths globally. Conventional treatments – including surgery, radiotherapy, and pharmacotherapy – are the foundational treatments. Non…
View article: Correlation of TP53 Genetic Alterations with p53 Immunohistochemical Expression and Their Prognostic Significance in DLBCL
Correlation of TP53 Genetic Alterations with p53 Immunohistochemical Expression and Their Prognostic Significance in DLBCL Open
TP53 genetic alterations represent a critical molecular feature in diffuse large B-cell lymphoma (DLBCL), with well-established associations with aggressive disease behavior and therapeutic resistance. However, significant controversy pers…
View article: A case of successful removal of 15 magnetic beads causing gastric penetration by endoscopic full-thickness resection
A case of successful removal of 15 magnetic beads causing gastric penetration by endoscopic full-thickness resection Open
View article: PD-1 inhibitors plus chemotherapy for refractory EBV-positive DLBCL: a retrospective analysis
PD-1 inhibitors plus chemotherapy for refractory EBV-positive DLBCL: a retrospective analysis Open
Background Immunochemotherapy has demonstrated a promising efficacy for a variety of B-cell lymphoma but has limited efficacy for Epstein–Barr virus-positive (EBV +) diffuse large B-cell lymphoma (DLBCL) that is refractory or relapsed to c…
View article: TRPS1, a sensitive marker for different histological and molecular types of breast cancer
TRPS1, a sensitive marker for different histological and molecular types of breast cancer Open
View article: Characteristics and Clinical Value of MYC, BCL2, and BCL6 Rearrangement Detected by Next-generation Sequencing in DLBCL
Characteristics and Clinical Value of MYC, BCL2, and BCL6 Rearrangement Detected by Next-generation Sequencing in DLBCL Open
MYC , BCL2, and BCL6 rearrangements are clinically important events of diffuse large B-cell lymphoma (DLBCL). The ability and clinical value of targeted next-generation sequencing (NGS) in the detection of these rearrangements in DLBCL hav…
View article: Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics
Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics Open
View article: Predicting central nervous system relapse in primary breast diffuse large B-cell lymphoma using the stage-modified IPI score: A retrospective cohort study
Predicting central nervous system relapse in primary breast diffuse large B-cell lymphoma using the stage-modified IPI score: A retrospective cohort study Open
View article: Response to anti-HER2 neoadjuvant chemotherapy in HER2-positive invasive breast cancers with different HER2 FISH patterns
Response to anti-HER2 neoadjuvant chemotherapy in HER2-positive invasive breast cancers with different HER2 FISH patterns Open
Aims Human epidermal growth factor receptor 2 (HER2)-positive patients with breast cancer may have different HER2/CEP17 ratios and HER2 copy numbers, with inconsistent responses to anti-HER2 neoadjuvant chemotherapy (NACT). Our study aimed…
View article: Yin Yang 1 expression predicts a favourable survival in diffuse large B-cell lymphoma
Yin Yang 1 expression predicts a favourable survival in diffuse large B-cell lymphoma Open
YY1 was frequently expressed in DLBCL, especially in those of GCB phenotype and with MYC/BCL2-DE. As an independent prognostic factor, YY1 expression could predict a favourable outcome in DLBCL. In addition, a complex regulatory mechanism …
View article: Supplementary Figure 2 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 2 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Enhanced expression of MET correlates with progression in human CRC.
View article: Supplementary Figure 6 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 6 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
IC50 determination of PF-04217903 and IFN-β in LoVo and SW620 cells.
View article: Data from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Data from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Purpose: BATF2, a novel IFN-stimulated gene, inhibits tumor cell proliferation, invasion, and migration. The objectives of this study were to determine how BATF2 expression is associated with colorectal cancer progression and…
View article: Supplementary Figure Legends, Tables 1 - 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure Legends, Tables 1 - 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Supplementary Table 1. The correlation of BATF2 expression with clinicopathological status in 148 patients with colorectal cancer. Supplementary Table 2. Multivariate Cox proportional hazard analysis of prognostic variables in CRC patients…
View article: Supplementary Figure 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Supplementary Figure 4 from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
siMET transfection arrests invasion of CRC cells.
View article: Data from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs
Data from BATF2 Deficiency Promotes Progression in Human Colorectal Cancer via Activation of HGF/MET Signaling: A Potential Rationale for Combining MET Inhibitors with IFNs Open
Purpose: BATF2, a novel IFN-stimulated gene, inhibits tumor cell proliferation, invasion, and migration. The objectives of this study were to determine how BATF2 expression is associated with colorectal cancer progression and…
View article: 98P Short-course radiotherapy based total neoadjuvant therapy combined with tislelizumab in the treatment of locally advanced rectal cancer: Mid-term report of a phase II, open-label, randomized controlled trial
98P Short-course radiotherapy based total neoadjuvant therapy combined with tislelizumab in the treatment of locally advanced rectal cancer: Mid-term report of a phase II, open-label, randomized controlled trial Open
Short-course radiotherapy (SCRT) based Total Neoadjuvant Therapy (TNT) has been used for the treatment of locally advanced rectal cancer (LARC). However, studies show that the pCR rate of patients still hovers around 20%. It has been found…
View article: <scp><i>IRF4</i></scp> rearrangement may predict favorable prognosis in children and young adults with primary head and neck large B‐cell lymphoma
<span><i>IRF4</i></span> rearrangement may predict favorable prognosis in children and young adults with primary head and neck large B‐cell lymphoma Open
Purpose Large B‐cell lymphoma with IRF4 rearrangement (LBCL, IRF4 +) has been recently recognized as a specific entity that is frequently associated with young age and favorable prognosis. However, whether the good outcome of the disease i…
View article: Renieramycin T Inhibits Melanoma B16F10 Cell Metastasis and Invasion via Regulating Nrf2 and STAT3 Signaling Pathways
Renieramycin T Inhibits Melanoma B16F10 Cell Metastasis and Invasion via Regulating Nrf2 and STAT3 Signaling Pathways Open
As one of marine tetrahydroisoquinoline alkaloids, renieramycin T plays a significant role in inhibiting tumor metastasis and invasion. However, the effect of renieramycin T on inflammation-related tumor metastasis and invasion is still un…
View article: Prognostic significance of clinical characteristics and <sup>18</sup>Fluorodeoxyglucose-positron emission tomography/computed tomography quantitative parameters in patients with primary mediastinal B-cell lymphoma
Prognostic significance of clinical characteristics and <sup>18</sup>Fluorodeoxyglucose-positron emission tomography/computed tomography quantitative parameters in patients with primary mediastinal B-cell lymphoma Open
Objective Primary mediastinal B-cell lymphoma (PMBCL) lacks standard treatment regimens. This study aimed to identify the disease’s clinical features and prognostic factors. Methods This retrospective study included 56 patients with PMBCL.…
View article: Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing Suggestions
Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing Suggestions Open
Background: Expert consensus on BRCA1/2 genetic testing and clinical application in Chinese breast cancer patients recommends that BRCA1/2 testing should be performed in those with clinical risk factors, such as an early onset, triple-nega…
View article: Genetic and immune characteristics of multiple primary lung cancers and lung metastases
Genetic and immune characteristics of multiple primary lung cancers and lung metastases Open
Background To explore the genetic and immunophenotyping heterogeneities between patients with intrapulmonary metastasis (IPM) or multiple primary lung cancer (MPLC). Methods Whole exome sequencing (WES) and transcriptome sequencing (RNA‐se…
View article: The Clinical Features and Survival Outcome of 107 Newly Diagnosed Advanced Stage Extranodal NK/T-Cell Lymphoma Cases: A Triple-Center Study
The Clinical Features and Survival Outcome of 107 Newly Diagnosed Advanced Stage Extranodal NK/T-Cell Lymphoma Cases: A Triple-Center Study Open
Our results demonstrated that L-asp containing chemotherapy could provide favorable survival outcomes in patients with advanced stage ENKTL.
View article: Characterization of Artificial Pneumothorax-Unrelated Pyothorax-Associated Lymphoma
Characterization of Artificial Pneumothorax-Unrelated Pyothorax-Associated Lymphoma Open
Pyothorax-associated lymphoma (PAL) is a rare disease developing from a long-term pleural cavity inflammation. Most reported PAL cases have a history of artificial pneumothorax. However, the clinical features of artificial pneumothorax-unr…
View article: The clinicopathological relevance of uniform CD56 expression in anaplastic large cell lymphoma: a retrospective analysis of 18 cases
The clinicopathological relevance of uniform CD56 expression in anaplastic large cell lymphoma: a retrospective analysis of 18 cases Open
View article: Universal extracellular vesicles and PD-L1+ extracellular vesicles detected by single molecule array technology as circulating biomarkers for diffuse large B cell lymphoma
Universal extracellular vesicles and PD-L1+ extracellular vesicles detected by single molecule array technology as circulating biomarkers for diffuse large B cell lymphoma Open
Plasma extracellular vesicles (EVs) have been reported to be a promising source of diagnostic and prognostic biomarkers in various cancers. However, further research in this area is needed due to the limitations of circulating extracellula…
View article: Clinical Significance of Circulating Exosomal PD-L1 and Soluble PD-L1 in Nasal-type NK/T-cell Lymphoma Patients Receiving VIPD Containing Chemotherapy
Clinical Significance of Circulating Exosomal PD-L1 and Soluble PD-L1 in Nasal-type NK/T-cell Lymphoma Patients Receiving VIPD Containing Chemotherapy Open
Background: Several studies showed that circulating exosomal PD-L1 was associated with immunosuppression and prognosis in cancer patients. However, its prognostic value in extranodal NK/T cell lymphoma (ENKTCL) was poorly understood.Method…
View article: Invasive apocrine carcinoma of the breast: clinicopathologic features and comprehensive genomic profiling of 18 pure triple-negative apocrine carcinomas
Invasive apocrine carcinoma of the breast: clinicopathologic features and comprehensive genomic profiling of 18 pure triple-negative apocrine carcinomas Open
View article: Microsatellite instability and its associations with the clinicopathologic characteristics of diffuse large B‐cell lymphoma
Microsatellite instability and its associations with the clinicopathologic characteristics of diffuse large B‐cell lymphoma Open
Microsatellite instability (MSI) has been investigated as a prognostic and predictive factor for chemotherapy in colorectal cancer and has recently been demonstrated to be predictive of the PD‐1/PD‐L1 checkpoint blockade response in variou…
View article: Intense basolateral membrane staining indicates HER2 positivity in invasive micropapillary breast carcinoma
Intense basolateral membrane staining indicates HER2 positivity in invasive micropapillary breast carcinoma Open