Nanfang Xu
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Author Swipe
View article: The Relationship Between Postoperative Variation of Adjacent Segment Three‐Dimensional Kinematics and Postoperative <scp>PI</scp> ‐ <scp>LL</scp> in Patients With Degenerative Lumbar Scoliosis After Short Segment Fixation
The Relationship Between Postoperative Variation of Adjacent Segment Three‐Dimensional Kinematics and Postoperative <span>PI</span> ‐ <span>LL</span> in Patients With Degenerative Lumbar Scoliosis After Short Segment Fixation Open
Objective The etiology of adjacent segment diseases and proximal junctional kyphosis has been related to biomechanical alterations after spinal operation. This study investigated the variation in pre‐ and postoperative range of motion in a…
View article: Surgical management strategies for atlantoaxial instability/dislocation in down syndrome
Surgical management strategies for atlantoaxial instability/dislocation in down syndrome Open
View article: Virtual reality force feedback spine surgery simulator training for pedicle screw placement: assessing the impact of seniority and spinal region
Virtual reality force feedback spine surgery simulator training for pedicle screw placement: assessing the impact of seniority and spinal region Open
View article: Deep Learning Approach for Automated Estimation of 3D Vertebral Orientation of the Lumbar Spine
Deep Learning Approach for Automated Estimation of 3D Vertebral Orientation of the Lumbar Spine Open
Lumbar degenerative disc diseases constitute a major contributor to lower back pain. In pursuit of an enhanced understanding of lumbar degenerative pathology and the development of more effective treatment modalities, the application of pr…
View article: Artificial intelligence in spine surgery
Artificial intelligence in spine surgery Open
Artificial intelligence (AI) technology has rapidly advanced in recent years, particularly in fields such as computer vision and natural language processing, where significant breakthroughs have been made. The emergence of large language m…
View article: Examining the Role of Large Language Models in Orthopedics: Systematic Review
Examining the Role of Large Language Models in Orthopedics: Systematic Review Open
Background Large language models (LLMs) can understand natural language and generate corresponding text, images, and even videos based on prompts, which holds great potential in medical scenarios. Orthopedics is a significant branch of med…
View article: Efficacy of Preoperative Autologous Blood Donation for Surgical Treatment of Thoracic Spinal Stenosis: A Propensity‐Matched Cohort Study
Efficacy of Preoperative Autologous Blood Donation for Surgical Treatment of Thoracic Spinal Stenosis: A Propensity‐Matched Cohort Study Open
Objective Thoracic spinal stenosis (TSS) surgeries necessitate a substantial amount of allogeneic blood resources. However, the efficacy of preoperative autologous blood donation (PABD) in TSS surgery has not been clearly evaluated. Theref…
View article: A machine learning based quantification system for automated diagnosis of lumbar spondylolisthesis on spinal X-rays
A machine learning based quantification system for automated diagnosis of lumbar spondylolisthesis on spinal X-rays Open
View article: Using additive manufacturing for craniocervical reconstruction in traditionally challenging cases
Using additive manufacturing for craniocervical reconstruction in traditionally challenging cases Open
Study Design: Retrospective case series. Objectives The aim of this study was to evaluate the clinical outcomes and effectiveness of using 3D printed implants in upper cervical spine and occipitocervical junction surgery. Methods C2 primar…
View article: Randomized controlled study protocol for surgical treatment of irreducible atlantoaxial dislocation
Randomized controlled study protocol for surgical treatment of irreducible atlantoaxial dislocation Open
Introduction: Irreducible atlantoaxial dislocation (IAAD) poses a complex surgical challenge, necessitating a critical evaluation of available strategies. Surgical approaches under consideration encompass the simple posterior approach and …
View article: Genetic insights into the ‘sandwich fusion’ subtype of Klippel–Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing
Genetic insights into the ‘sandwich fusion’ subtype of Klippel–Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing Open
Background Klippel–Feil syndrome (KFS) is a rare congenital disorder characterized by the fusion of two or more cervical vertebrae during early prenatal development. This fusion results from a failure of segmentation during the first trime…
View article: The mutational burden in os odontoideum patients
The mutational burden in os odontoideum patients Open
Background Os odontoideum(OO) is a rare bone malformation at the craniovertebral junction, the presence of which can lead to potential instability of atlantoaxial joints. The cause, prevalence and treatment of OO are still controversial. B…
View article: Whole‐Exome Sequencing Analysis Identifies Risk Genes in Atlantoaxial Dislocation Patients with Sandwich Fusion
Whole‐Exome Sequencing Analysis Identifies Risk Genes in Atlantoaxial Dislocation Patients with Sandwich Fusion Open
Sandwich fusion of Klippel‐Feil syndrome (KFS), which is a rare congenital disorder involving the fusion of cervical vertebrae, poses significant challenges in the diagnosis and treatment of atlantoaxial dislocation (AAD). While the disord…
View article: Preoperative radiological indicators for prediction of difficult laryngoscopy in patients with atlantoaxial dislocation
Preoperative radiological indicators for prediction of difficult laryngoscopy in patients with atlantoaxial dislocation Open
ΔC1C2D could be a valuable radiologic predictor for difficult laryngoscopy in patients with AAD.
View article: Genetic Insights into the 'Sandwich Fusion' Subtype of Klippel-Feil Syndrome: Novel FGFR2 Mutations Identified by 21 cases of Whole-Exome Sequencing
Genetic Insights into the 'Sandwich Fusion' Subtype of Klippel-Feil Syndrome: Novel FGFR2 Mutations Identified by 21 cases of Whole-Exome Sequencing Open
Background Klippel-Feil syndrome (KFS) is a rare congenital disorder characterized by the fusion of two or more cervical vertebrae during early prenatal development. This fusion results from a failure of segmentation during the first trime…
View article: Correction: iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin <i>in vitro</i>
Correction: iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin <i>in vitro</i> Open
View article: Medium to long term follow-up of survival and quality of life in patients with primary tumors of the cervical spine: Experience From a large single center
Medium to long term follow-up of survival and quality of life in patients with primary tumors of the cervical spine: Experience From a large single center Open
Objectives To evaluate the survival and medium to long term health-related quality of life (HRQoL) of patients with primary cervical spinal tumors in a cross-sectional study and to identify any significant associations with demographic or …
View article: Risk Mutations Identified by Whole-Exome Sequencing in 21 Patients with the 'Sandwich Fusion' Subtype of Klippel-Feil Syndrome
Risk Mutations Identified by Whole-Exome Sequencing in 21 Patients with the 'Sandwich Fusion' Subtype of Klippel-Feil Syndrome Open
View article: Facile Construction of Hybrid Hydrogels with High Strength and Biocompatibility for Cranial Bone Regeneration
Facile Construction of Hybrid Hydrogels with High Strength and Biocompatibility for Cranial Bone Regeneration Open
The significant efforts being made towards the utilization of artificial soft materials holds considerable promise for developing tissue engineering scaffolds for bone-related diseases in clinics. However, most of these biomaterials cannot…
View article: Cross-cultural adaptation and validation of the Chinese version of the Spine Oncology Study Group Outcomes Questionnaire
Cross-cultural adaptation and validation of the Chinese version of the Spine Oncology Study Group Outcomes Questionnaire Open
Background context Patients with spinal metastases always have a poor health-related quality of life (HRQoL) and disease- and treatment-related adverse outcomes. The Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ) has been verif…
View article: A sustained release of alendronate from an injectable tetra-PEG hydrogel for efficient bone repair
A sustained release of alendronate from an injectable tetra-PEG hydrogel for efficient bone repair Open
Significant efforts on construction of smart drug delivery for developing minimally invasive gelling system to prolong local delivery of bisphosphonates are considered as promising perspectives for the bone-related diseases, which provide …
View article: Prospective study of preoperative autologous blood donation for patients with high risk of allogeneic blood transfusion in lumbar fusion surgery: a study protocol of a randomised controlled trial
Prospective study of preoperative autologous blood donation for patients with high risk of allogeneic blood transfusion in lumbar fusion surgery: a study protocol of a randomised controlled trial Open
Introduction Preoperative autologous blood donation (PABD) can be used to reduce the exposure of allogeneic blood transfusion in patients undergoing elective surgery. Better blood management to avoid anaemia and reduce allogeneic blood tra…
View article: Accuracy of postoperative recall by degenerative cervical myelopathy patients using the modified Japanese Orthopaedic Association scale
Accuracy of postoperative recall by degenerative cervical myelopathy patients using the modified Japanese Orthopaedic Association scale Open
It is necessary to select post-operative patients who need to pay attention according to the three factors of post-operative time, gender, and age, that is, patients with large RE should be given early or timely psychological counseling an…
View article: Vertebral Artery Variations at the Craniovertebral Junction in “Sandwich” Atlantoaxial Dislocation Patients
Vertebral Artery Variations at the Craniovertebral Junction in “Sandwich” Atlantoaxial Dislocation Patients Open
Objective: To summarize the vertebral artery (VA) pattern of 96 “sandwich” atlantoaxial dislocation (AAD) patients and to describe the strategies of reducing the injury of VA during surgery.Methods: From 2009 to 2020, we retrospectively re…
View article: Reliability and validity of simplified Chinese version of the Italian spine youth quality of life questionnaire in adolescents with idiopathic scoliosis
Reliability and validity of simplified Chinese version of the Italian spine youth quality of life questionnaire in adolescents with idiopathic scoliosis Open
View article: Translation and validation of the Chinese version of Brace Questionnaire (BrQ)
Translation and validation of the Chinese version of Brace Questionnaire (BrQ) Open
Cross-cultural translation and validation demonstrated excellent reliability, high internal consistency and satisfactory concurrent validity of the Chinese version of BrQ.
View article: A novel 3D-printed locking cage for anterior atlantoaxial fixation and fusion: case report and in vitro biomechanical evaluation
A novel 3D-printed locking cage for anterior atlantoaxial fixation and fusion: case report and in vitro biomechanical evaluation Open
View article: Atlantoaxial dislocation with congenital “sandwich fusion” in the craniovertebral junction: a retrospective case series of 70 patients
Atlantoaxial dislocation with congenital “sandwich fusion” in the craniovertebral junction: a retrospective case series of 70 patients Open
View article: 3D-printed brace in the treatment of adolescent idiopathic scoliosis: a study protocol of a prospective randomised controlled trial
3D-printed brace in the treatment of adolescent idiopathic scoliosis: a study protocol of a prospective randomised controlled trial Open
Introduction Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine. Brace treatment is effective for eligible patients with AIS and the effectiveness is significantly correlated with the average brace-wear tim…
View article: A prospective randomized cohort study on 3D-printed artificial vertebral body in single-level anterior cervical corpectomy for cervical spondylotic myelopathy
A prospective randomized cohort study on 3D-printed artificial vertebral body in single-level anterior cervical corpectomy for cervical spondylotic myelopathy Open
For CSM patients undergoing SL-ACCF, the EBM-AVB group demonstrated comparable outcomes regarding patient cervical alignment, neurologic function, and HRQoL in comparison with the TMC group. Furthermore, the use of EBM-AVB was associated w…