Nannan Dong
YOU?
Author Swipe
View article: Mucin phenotype-based deep learning framework for intestinal metaplasia-carcinogenesis progression prediction
Mucin phenotype-based deep learning framework for intestinal metaplasia-carcinogenesis progression prediction Open
This study decodes spatiotemporal mucin dynamics in gastric carcinogenesis, revealing gastric-type markers (MUC5AC/MUC6) decline progressively while intestinal-type markers (MUC2/CD10) peak in gastric intestinal metaplasia (GIM) before dec…
View article: A glutamyl–tRNA reductase and its binding protein promote transitory starch biosynthesis and enhance grain quality and yield in rice
A glutamyl–tRNA reductase and its binding protein promote transitory starch biosynthesis and enhance grain quality and yield in rice Open
Transitory starch in rice leaves is critical for temporary carbon storage, plant growth, and subsequent grain filling, yet the regulatory mechanisms underlying its biosynthesis remain poorly understood. Here, we found that Leaf Starch Defi…
View article: Alpha-asarone relieves nasal inflammation, epithelial barrier damage, and mitochondrial damage in allergic rhinitis by inhibiting mitochondrial ROS via the SIRT1/PGC-1α pathway
Alpha-asarone relieves nasal inflammation, epithelial barrier damage, and mitochondrial damage in allergic rhinitis by inhibiting mitochondrial ROS via the SIRT1/PGC-1α pathway Open
Allergic rhinitis (AR), a chronic inflammatory disease characterized by nasal congestion, sneezing, itching, and rhinorrhea, significantly impairs the quality of life for those affected. Current treatments have limitations due to adverse e…
View article: Genome-Wide Association Analysis Identifies Loci for Powdery Mildew Resistance in Wheat
Genome-Wide Association Analysis Identifies Loci for Powdery Mildew Resistance in Wheat Open
Wheat (Triticum aestivum L.), a staple crop of global significance, faces constant biotic stress threats, with powdery mildew caused by Blumeria graminis f. sp. tritici (Bgt) being particularly damaging. In this study, a multi-year single-…
View article: Identification of Sucrose Transporter (SUT) Genes Regulating Rice Yield and Quality
Identification of Sucrose Transporter (SUT) Genes Regulating Rice Yield and Quality Open
View article: Molecular mapping and validation of quantitative trait loci for content of micronutrients in wheat grain
Molecular mapping and validation of quantitative trait loci for content of micronutrients in wheat grain Open
Manganese (Mn), iron (Fe), copper (Cu), zinc (Zn), and selenium (Se) are essential micronutrients for human health. However, the genetic basis for the content of Mn, Fe, Cu, Zn, and Se in wheat grains remains unclear. A recombinant inbred …
View article: A Multimodal Model for Predicting Gastric Cancer Risk and Implementing Precision Stratification Management in Populations Post-Gastroscopy Screening
A Multimodal Model for Predicting Gastric Cancer Risk and Implementing Precision Stratification Management in Populations Post-Gastroscopy Screening Open
View article: Retraction Note: Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells
Retraction Note: Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells Open
View article: A Novel Diagnostic Prediction Model for Distinguishing Between Tuberculous and Cryptococcal Meningitis
A Novel Diagnostic Prediction Model for Distinguishing Between Tuberculous and Cryptococcal Meningitis Open
Background and aim: Tuberculous meningitis (TBM) and cryptococcal meningitis (CM) are easily misdiagnosed due to atypical clinical symptoms. It is difficult for physcians to achieve a rapid and accurate differential diagnosis of TBM…
View article: A molecular module improves rice grain quality and yield at high temperatures
A molecular module improves rice grain quality and yield at high temperatures Open
Excessive temperatures during grain filling can compromise endosperm starch biosynthesis and decrease grain quality and yield in rice. However, the molecular mechanisms underlying these remain unclear. Here, we show that heat shock protein…
View article: Genome-Wide Analysis of Heat Shock Protein Family and Identification of Their Functions in Rice Quality and Yield
Genome-Wide Analysis of Heat Shock Protein Family and Identification of Their Functions in Rice Quality and Yield Open
Heat shock proteins (Hsps), acting as molecular chaperones, play a pivotal role in plant responses to environmental stress. In this study, we found a total of 192 genes encoding Hsps, which are distributed across all 12 chromosomes, with h…
View article: Uncommon Presentation of Systemic Lupus Erythematosus: Intracranial Mass Lesions as the First Manifestation
Uncommon Presentation of Systemic Lupus Erythematosus: Intracranial Mass Lesions as the First Manifestation Open
BACKGROUND Multi-system damage is a hallmark of systemic lupus erythematosus (SLE), a chronic systemic autoimmune disease. The typical initial symptoms of SLE are arthritis and dermatosis, whereas the presence of intracranial mass lesions …
View article: OsLESV and OsESV1 promote transitory and storage starch biosynthesis to determine rice grain quality and yield
OsLESV and OsESV1 promote transitory and storage starch biosynthesis to determine rice grain quality and yield Open
View article: Table of Contents
Table of Contents Open
View article: Response to letter to the editor regarding "Is relying on RNFL specific enough to identify any changes in the CNS?"
Response to letter to the editor regarding "Is relying on RNFL specific enough to identify any changes in the CNS?" Open
View article: Stable and Environmentally Benign Nanofluids for Direct Absorption Solar Collectors Based on Natural Deep Eutectic Solvents
Stable and Environmentally Benign Nanofluids for Direct Absorption Solar Collectors Based on Natural Deep Eutectic Solvents Open
View article: Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women
Evaluation of choroidal thickness and retinal nerve fiber layer thickness in Chinese pregnant women and healthy non-pregnant women Open
The choroidal thickness in pregnant women was found to be thicker than the control group, regardless of macular or optic disc location. Findings of RNFL thickening might indicate subclinical involvement of the central nervous system.
View article: OsLEA1b Modulates Starch Biosynthesis at High Temperatures in Rice
OsLEA1b Modulates Starch Biosynthesis at High Temperatures in Rice Open
High temperatures accelerate the accumulation of storage material in seeds, often leading to defects in grain filling. However, the mechanisms regulating grain filling at high temperatures remain unknown. Here, we want to explore the quali…
View article: Genome-Wide Analysis and Functional Characterization of Pyruvate Kinase (PK) Gene Family Modulating Rice Yield and Quality
Genome-Wide Analysis and Functional Characterization of Pyruvate Kinase (PK) Gene Family Modulating Rice Yield and Quality Open
Pyruvate kinase (PK) is one of the three rate-limiting enzymes of glycolysis, and it plays a pivotal role in energy metabolism. In this study, we have identified 10 PK genes from the rice genome. Initially, these genes were divided into tw…
View article: A Novel Diagnostic Prediction Model to Distinguish Tuberculous Meningitis and Cryptococcal Meningitis
A Novel Diagnostic Prediction Model to Distinguish Tuberculous Meningitis and Cryptococcal Meningitis Open
View article: Xuhui Runway Park Methods
Xuhui Runway Park Methods Open
View article: Peer Review #3 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.1)"
Peer Review #3 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.1)" Open
Background：Gastric gland mucin is important for maintaining the basic function of the gastric mucosa, protecting it from foreign substances and reducing the occurrence of gastric diseases.Exploring the phenotype of gastric gland mucus chan…
View article: Peer Review #1 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.1)"
Peer Review #1 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.1)" Open
Background：Gastric gland mucin is important for maintaining the basic function of the gastric mucosa, protecting it from foreign substances and reducing the occurrence of gastric diseases.Exploring the phenotype of gastric gland mucus chan…
View article: Peer Review #2 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.1)"
Peer Review #2 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.1)" Open
Background：Gastric gland mucin is important for maintaining the basic function of the gastric mucosa, protecting it from foreign substances and reducing the occurrence of gastric diseases.Exploring the phenotype of gastric gland mucus chan…
View article: Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer
Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer Open
Background Gastric gland mucin is important for maintaining the basic function of the gastric mucosa, protecting it from foreign substances and reducing the occurrence of gastric diseases. Exploring the phenotype of gastric gland mucus cha…
View article: Peer Review #1 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.2)"
Peer Review #1 of "Phenotype characteristics of gastric epithelial mucus in patients with different gastric diseases: from superficial gastritis to gastric cancer (v0.2)" Open
Background：Gastric gland mucin is important for maintaining the basic function of the gastric mucosa, protecting it from foreign substances and reducing the occurrence of gastric diseases.Exploring the phenotype of gastric gland mucus chan…
View article: RETRACTED ARTICLE: Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells
RETRACTED ARTICLE: Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells Open
View article: TAIPU CANAL AS A REGIONAL SPINE: A PROTOTYPICAL APPROACH TO TERRITORIAL PLANNING
TAIPU CANAL AS A REGIONAL SPINE: A PROTOTYPICAL APPROACH TO TERRITORIAL PLANNING Open
Since 2018, the integrated regional development of the Yangtze River Delta has been subjected as a national strategy to intensify the interconnection between its cities. However, the questions of open space conservation and planning have s…
View article: PGC-MG7 combination could be used as a follow-up panel for monitoring dynamical progression of gastric precancerous diseases
PGC-MG7 combination could be used as a follow-up panel for monitoring dynamical progression of gastric precancerous diseases Open
Our data suggest that the "PGC-MG7+" pattern can be employed as a useful follow-up panel for detecting individuals with a high risk of GC, and the dynamic assessment of the follow-up panel needs multi-centre large-scale validation in the f…
View article: Protein expression trends of DNMT1 in gastrointestinal diseases: From benign to precancerous lesions to cancer
Protein expression trends of DNMT1 in gastrointestinal diseases: From benign to precancerous lesions to cancer Open
The overexpression of DNMT1 protein could effectively predict early GI cancers and severe precancerous lesions, which may have potential clinical application value.