Nanxia Zhang
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View article: Novel Light‐Promoted Bioorthogonal Reaction via Molecular Recombination for the Synthesis of Polysubstituted Pyrrole and Its Application in In Vitro and In Vivo Studies
Novel Light‐Promoted Bioorthogonal Reaction via Molecular Recombination for the Synthesis of Polysubstituted Pyrrole and Its Application in In Vitro and In Vivo Studies Open
Bioorthogonal chemistry has revolutionized organic, medicinal, and biochemical research by designing and developing selective and rapid reactions that do not interfere with biological processes. Despite significant advancements, the existi…
View article: Novel Light‐Promoted Bioorthogonal Reaction via Molecular Recombination for the Synthesis of Polysubstituted Pyrrole and Its Application in In Vitro and In Vivo Studies
Novel Light‐Promoted Bioorthogonal Reaction via Molecular Recombination for the Synthesis of Polysubstituted Pyrrole and Its Application in In Vitro and In Vivo Studies Open
Bioorthogonal chemistry has revolutionized organic, medicinal, and biochemical research by designing and developing selective and rapid reactions that do not interfere with biological processes. Despite significant advancements, the existi…
View article: Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment
Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment Open
NIK plays a crucial role in the noncanonical NF-κB signaling pathway associated with diverse inflammatory and autoimmune diseases. Our study presents compound 54, a novel NIK inhibitor, designed through a structure-based scaffold-hopping a…
View article: Dendritic polyethylene glycol-modified folate-nickel nanotubes as an efficient antitumor nano-metal medicine
Dendritic polyethylene glycol-modified folate-nickel nanotubes as an efficient antitumor nano-metal medicine Open
Metal-containing nanomaterials have attracted substantial research efforts due to their rich compositional and structural diversity as well as the broad possible applications. However, the most metal-containing nanomaterials are normally o…
View article: Highly Efficient Mesoporous Core-Shell Structured Ag@SiO2 Nanosphere as an Environmentally Friendly Catalyst for Hydrogenation of Nitrobenzene
Highly Efficient Mesoporous Core-Shell Structured Ag@SiO2 Nanosphere as an Environmentally Friendly Catalyst for Hydrogenation of Nitrobenzene Open
The size-uniformed mesoporous Ag@SiO2 nanospheres’ catalysts were prepared in one-pot step via reducing AgNO3 by different types of aldehyde, which could control the size of Ag@SiO2 NPs and exhibit excellent catalytic activity for the hydr…
View article: Phenylboronic Ester-Modified Anionic Micelles for ROS-Stimuli Response in HeLa Cell
Phenylboronic Ester-Modified Anionic Micelles for ROS-Stimuli Response in HeLa Cell Open
Smart polymers as ideal drug nanocarriers have attracted much attention due to the effective drug delivery, internalization and release once triggered by intracellular stimuli, as well as reduced cytotoxicity. We here reported the anionic …
View article: Mannose‐Modified Multi‐Walled Carbon Nanotubes as a Delivery Nanovector Optimizing the Antigen Presentation of Dendritic Cells
Mannose‐Modified Multi‐Walled Carbon Nanotubes as a Delivery Nanovector Optimizing the Antigen Presentation of Dendritic Cells Open
Dendritic cells (DCs) based cancer immunotherapy is largely dependent on adequate antigen delivery and efficient induction of DCs maturation to produce sufficient antigen presentation and ultimately lead to substantial activation of tumor‐…