Naoki Isobe
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View article: Production of S100A10 in the mammary glands of goats
Production of S100A10 in the mammary glands of goats Open
S100A10 is a calcium-binding protein associated with plasmin production in milk. However, the relationship of S100A10 production with inflammation and plasmin production in the mammary glands remains unclear. The present study was undertak…
View article: Far-infrared probing with PRIMA into particle acceleration associated with relativistic jets from active galactic nuclei
Far-infrared probing with PRIMA into particle acceleration associated with relativistic jets from active galactic nuclei Open
It is presented that the Probe far-Infrared Mission for Astrophysics (PRIMA) has a high potential to study particle acceleration phenomena associated with jets emanating from active galactic nuclei. A special focus is put on hot spots of r…
View article: Mammary leukocytes function of endotoxin tolerant goat induced by intrauterine infusion of lipopolysaccharide
Mammary leukocytes function of endotoxin tolerant goat induced by intrauterine infusion of lipopolysaccharide Open
A previous study found that repeated intrauterine infusions of lipopolysaccharide (LPS) followed by an LPS infusion into the mammary glands attenuated the mammary inflammatory response. This suggests that repeated LPS infusion into the ute…
View article: Effect of medium-chain fatty acid supplementation on feed intake, rumen fermentation, blood profile, and milk production of dairy cows in the transition period
Effect of medium-chain fatty acid supplementation on feed intake, rumen fermentation, blood profile, and milk production of dairy cows in the transition period Open
Medium-chain fatty acids (MCFA) are rapidly utilized by the liver as an energy source. However, the effects of feeding MCFA to dairy cows during the transition period and the subsequent effect on postpartum performance is not clear. Theref…
View article: Determining causal pathogens and inflammatory state of mastitis in dairy cows via Gram staining of precipitates in milk
Determining causal pathogens and inflammatory state of mastitis in dairy cows via Gram staining of precipitates in milk Open
Early detection of bovine mastitis-causing pathogens is necessary for treatment. As culturing methods are time-consuming, a more rapid detection technique is required. This study investigated the sensitivity, specificity, and detection lim…
View article: Interleukin 1 Receptor Antagonist (IL‐1ra) Production and Expression Dynamics in Mammary Glands After Lipopolysaccharide Infusion
Interleukin 1 Receptor Antagonist (IL‐1ra) Production and Expression Dynamics in Mammary Glands After Lipopolysaccharide Infusion Open
Interleukin‐1 receptor antagonist (IL‐1ra) is an anti‐inflammatory cytokine, whose balance with pro‐inflammatory cytokines affects the susceptibility to and severity of udder mastitis. In this study, we aimed to investigate the IL‐1ra dyna…
View article: Effects of Aging on the Microbiota and Inflammatory Status of the Intestinal and Oviductal Mucosa in Laying Hens
Effects of Aging on the Microbiota and Inflammatory Status of the Intestinal and Oviductal Mucosa in Laying Hens Open
Aging and inflammation of the intestinal and oviductal mucosa reduce egg production in laying hens. In mammals, microbiota changes in the intestine and reproductive mucosa are linked to aging and mucosal inflammation, but this relationship…
View article: Antimicrobial Component Concentrations in the Milk of Peripartum Goats
Antimicrobial Component Concentrations in the Milk of Peripartum Goats Open
The aim of this study was to investigate changes in milk conditions and antimicrobial components in goats during 8 weeks prepartum and 1 week postpartum. Milk was collected weekly from seven prepartum goats 8 weeks before the due day, imme…
View article: Relationship of teat canal score to milk somatic cell count, pathogen infection, and antimicrobial components in Holstein dairy cows
Relationship of teat canal score to milk somatic cell count, pathogen infection, and antimicrobial components in Holstein dairy cows Open
This study examined the relationship between teat canal score (TCS), somatic cell count (SCC), pathogen infection, and milk antimicrobial components in each quarter of milking cows. A total of 110 quarters of 28 healthy Holstein milking co…
View article: Changes in Antimicrobial Component Concentrations at the Onset of the Dry Period and Peripartum in Dairy Cows
Changes in Antimicrobial Component Concentrations at the Onset of the Dry Period and Peripartum in Dairy Cows Open
We aimed to clarify antimicrobial component (AMC) dynamics during the dry period in dairy cows and determine the impacts of varying somatic cell count (SCC) at the onset of the dry period on the subsequent changes in AMC concentrations in …
View article: Unique Physiological Mechanisms of Sperm Storage and Prolonged Sperm Survival in Hen Oviducts: A Review
Unique Physiological Mechanisms of Sperm Storage and Prolonged Sperm Survival in Hen Oviducts: A Review Open
Poultry sperm survive for extended periods within sperm storage tubules (SSTs) located at the uterovaginal junction (UVJ) of the oviduct, and their survival period is directly correlated with fertility. In this review, the mechanisms under…
View article: Effect of lactoferrin on biofilm formation of bovine mastitis-causing <i>Staphylococcus</i> species
Effect of lactoferrin on biofilm formation of bovine mastitis-causing <i>Staphylococcus</i> species Open
The most common bovine mastitis pathogen is the Staphylococcus species, consisting of Staphylococcus aureus and non-aureus staphylococci (NAS). Lactoferrin (Lf) is an iron-binding protein with antimicrobial and antibiofilm properties. Lf h…
View article: Systematic Study of the Inner Structure of Molecular Tori in Nearby U/LIRGs Using Velocity Decomposition of CO Rovibrational Absorption Lines*
Systematic Study of the Inner Structure of Molecular Tori in Nearby U/LIRGs Using Velocity Decomposition of CO Rovibrational Absorption Lines* Open
Determining the inner structure of the molecular torus around an active galactic nucleus is essential for understanding its formation mechanism. However, spatially resolving the torus is difficult because of its small size. To probe the cl…
View article: Colchicine can keep the viability of bacteria in mastitic milk by preventing leukocyte phagocytosis in dairy cow and goat
Colchicine can keep the viability of bacteria in mastitic milk by preventing leukocyte phagocytosis in dairy cow and goat Open
Despite the occurrence of mastitis, no bacteria were detected in any of the milk samples after culture. This is partially because the neutrophils present in milk phagocytose bacteria during milk preservation. In this study, we investigated…
View article: Systematic Study of the Inner Structure of Molecular Tori in Nearby U/LIRGs using Velocity Decomposition of CO Rovibrational Absorption Lines
Systematic Study of the Inner Structure of Molecular Tori in Nearby U/LIRGs using Velocity Decomposition of CO Rovibrational Absorption Lines Open
Determining the inner structure of the molecular torus around an active galactic nucleus is essential for understanding its formation mechanism. However, spatially resolving the torus is difficult because of its small size. To probe the cl…
View article: JASMINE image simulator for high-precision astrometry and photometry
JASMINE image simulator for high-precision astrometry and photometry Open
JASMINE is a Japanese planned space mission that aims to reveal the formation\nhistory of our Galaxy and discover habitable exoEarths. For these objectives,\nthe JASMINE satellite performs high-precision astrometric observations of the\nGa…
View article: JASMINE: Near-infrared astrometry and time-series photometry science
JASMINE: Near-infrared astrometry and time-series photometry science Open
The Japan Astrometry Satellite Mission for INfrared Exploration (JASMINE) is a planned M-class science space mission by the Institute of Space and Astronautical Science, the Japan Aerospace Exploration Agency. JASMINE has two main science …
View article: NLRC5 expression profile in the oviduct of laying hens and its changes following estradiol treatment in induced molting hens
NLRC5 expression profile in the oviduct of laying hens and its changes following estradiol treatment in induced molting hens Open
The innate immune defense system is initiated by recognizing components of microorganisms by different families of receptors such as TLRs and the intracellular NLR family. Among the NLR family, NLRC5 recognizes pathogenic components of mic…
View article: Effect of different inflammation states on the antimicrobial components in milk of goat udders after milking cessation
Effect of different inflammation states on the antimicrobial components in milk of goat udders after milking cessation Open
The aim of this study was to examine the effects of milking cessation under different inflammatory conditions on the changes in antimicrobial components in milk and the process of mammary gland involution. Twenty udder halves were divided …
View article: Effect of milking time on yield, composition, and antimicrobial components of milk in lactating goats
Effect of milking time on yield, composition, and antimicrobial components of milk in lactating goats Open
Various studies have attempted to improve the milk yield and composition in dairy animals. However, no study has examined the effects of milking at different times on milk yield and composition. Therefore, this study aimed to compare the y…
View article: Concentrations of antimicrobial components in milk of Japanese Black cows and their differences from dairy cows
Concentrations of antimicrobial components in milk of Japanese Black cows and their differences from dairy cows Open
The components of milk from beef cows remain to be elucidated. This study examined the differences in the antimicrobial components of milk between dairy and beef cows. Quarter milk was collected from both Japanese Black (beef type) and Hol…
View article: Innate Immune Training in Chickens for Improved Defense against Pathogens: A Review
Innate Immune Training in Chickens for Improved Defense against Pathogens: A Review Open
The avian immune system plays a vital role in poultry production to obtain good productibility and products that are safe and of high quality. Historically, adaptive immunity has been the main target of vaccination. However, over the past …
View article: Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands
Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands Open
In the mammary glands, production of antimicrobial components and formation of less-permeable tight junctions (TJs) are important for safe milk production. Previously, we reported that local heat treatment of udders using disposable heatin…
View article: ALMA ACA Detection of Submillimeter Emission Associated with the Western Hot Spot of the Radio Galaxy Pictor A
ALMA ACA Detection of Submillimeter Emission Associated with the Western Hot Spot of the Radio Galaxy Pictor A Open
In order to investigate the far-infrared excess detected from the western hot spot of the radio galaxy Pictor A with the Herschel observatory, submillimeter photometry is performed with the Atacama Compact Array (ACA) of the Atacama Large …
View article: JASMINE: Near-Infrared Astrometry and Time Series Photometry Science
JASMINE: Near-Infrared Astrometry and Time Series Photometry Science Open
Japan Astrometry Satellite Mission for INfrared Exploration (JASMINE) is a planned M-class science space mission by the Institute of Space and Astronautical Science, the Japan Aerospace Exploration Agency. JASMINE has two main science goal…