Naomichi Kondo
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View article: Tcf21 modulates fibroblast activation and promotes cardiac fibrosis after injury via Pdgfrb signaling
Tcf21 modulates fibroblast activation and promotes cardiac fibrosis after injury via Pdgfrb signaling Open
Transformation of cardiac fibroblasts into matrix-producing myofibroblasts plays an important role in tissue repair and fibrosis after myocardial injury. Tcf21 is a basic helix-loop-helix transcription factor that is essential for the deve…
View article: Pericardial Grafting of Cardiac Progenitor Cells in Self-Assembling Peptide Scaffold Improves Cardiac Function After Myocardial Infarction
Pericardial Grafting of Cardiac Progenitor Cells in Self-Assembling Peptide Scaffold Improves Cardiac Function After Myocardial Infarction Open
Many studies have explored cardiac progenitor cell (CPC) therapy for heart disease. However, optimal scaffolds are needed to ensure the engraftment of transplanted cells. We produced a three-dimensional hydrogel scaffold (CPC-PRGmx) in whi…