Naoya Matsumoto
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View article: Temporal Changes in Epicardial Adipose Tissue and Left Atrial Substrate After Atrial Fibrillation Ablation: Implications for Procedural Success
Temporal Changes in Epicardial Adipose Tissue and Left Atrial Substrate After Atrial Fibrillation Ablation: Implications for Procedural Success Open
Background Ganglionated plexi (GPs) within epicardial adipose tissue (EAT) are involved in the initiation and maintenance of atrial fibrillation (AF), yet the effects of catheter ablation on EAT volume and GP activity remain unclear. Metho…
View article: Pyridoxamine as a potential scavenger of neurotoxic dopamine quinone: Inhibition of dopamine-induced α-synuclein oligomerization
Pyridoxamine as a potential scavenger of neurotoxic dopamine quinone: Inhibition of dopamine-induced α-synuclein oligomerization Open
Parkinson’s disease (PD) is a neurodegenerative disease characterized by loss of dopaminergic neurons causing reduced levels of dopamine (DA), and the presence of Lewy bodies, whose main component is fibrillar α-synuclein (α-Syn). DA is ea…
View article: Clinical Significance of Early Computed Tomography Scan on Thrombus Regression Rate in Acute Pulmonary Embolism: Insights from the SAKURA PE/DVT REGISTRY
Clinical Significance of Early Computed Tomography Scan on Thrombus Regression Rate in Acute Pulmonary Embolism: Insights from the SAKURA PE/DVT REGISTRY Open
Substantial thrombus regression and a low incidence of VTE and bleeding support the effectiveness of DOACs. Terminating intensive therapy in one-third of the rivaroxaban group after 2-week CT monitoring did not increase the occurrence of V…
View article: Optimal Targeted Temperature Management for Patients with Post-Cardiac Arrest Syndrome
Optimal Targeted Temperature Management for Patients with Post-Cardiac Arrest Syndrome Open
Background: To prevent hypoxic–ischemic brain damage in patients with post-cardiac arrest syndrome (PCAS), international guidelines have emphasized performing targeted temperature management (TTM). However, the most optimal targeted core t…
View article: Impella Effects on Reverse Myocardial Remodeling in Anterior ST-Elevation Myocardial Infarction: Insights from a Comprehensive Analysis of Acute and Chronic MRI Findings
Impella Effects on Reverse Myocardial Remodeling in Anterior ST-Elevation Myocardial Infarction: Insights from a Comprehensive Analysis of Acute and Chronic MRI Findings Open
Background Late adverse myocardial remodeling after ST elevation myocardial infarction (STEMI) is strongly associated with cardiac death. Global Longitudinal strain (GLS) and circumferential diastolic strain rate (CDSR) derived cardiovascu…
View article: RotaWire™ entrapment in distal right coronary artery in dialysis patient
RotaWire™ entrapment in distal right coronary artery in dialysis patient Open
Key Clinical Message Rotablation had been performed on a highly calcified lesion, enabling various devices to be brought distally for removal of the Entrapped RotaWire.
View article: Association between an Early Revascularization Strategy and Major Cardiac Events Based on Left Ventricular Dyssynchrony in Patients at Intermediate Risk of Major Cardiac Events Using the J-ACCESS Risk Model
Association between an Early Revascularization Strategy and Major Cardiac Events Based on Left Ventricular Dyssynchrony in Patients at Intermediate Risk of Major Cardiac Events Using the J-ACCESS Risk Model Open
Objective This retrospective study aimed to investigate the association between therapeutic strategies and the development of major cardiac events (MCEs) in intermediate-risk patients by using the the Japanese Assessment of Cardiac Events …
View article: Cardiac Acoustic Biomarkers in Patients with Heart Failure during Cardiopulmonary Exercise Testing: An Exploratory Study
Cardiac Acoustic Biomarkers in Patients with Heart Failure during Cardiopulmonary Exercise Testing: An Exploratory Study Open
Objective Exercise therapy as part of cardiac rehabilitation is one of the most effective treatments for patients with chronic heart failure (HF). The anaerobic threshold (AT) determined by an exhaled gas analysis during cardiopulmonary ex…
View article: Disease-Specific Tests
Disease-Specific Tests Open
View article: Current therapeutic strategies for acute kidney injury
Current therapeutic strategies for acute kidney injury Open
Acute kidney injury (AKI) is an emerging public health problem worldwide and is associated with high morbidity and mortality. The high mortality rate can be attributed to the lack of pharmacological therapies to prevent and treat AKI. Rena…
View article: Higher frequency of fish intake and healthy lifestyle behaviors may be associated with a lower platelet count in Japan: Implication for the anti-atherosclerotic effect of fish intake
Higher frequency of fish intake and healthy lifestyle behaviors may be associated with a lower platelet count in Japan: Implication for the anti-atherosclerotic effect of fish intake Open
Higher fish intake and healthier lifestyle behaviors may be comprehensively associated with lower PLCs. The intake of N-3 PUFA with anti-inflammatory effects, rich in fish, may also be related to the lower PLC. This association may explain…
View article: External Validation of the HELT-E<sub>2</sub>S<sub>2</sub> Score in Japanese Patients With Nonvalvular Atrial Fibrillation ― A Pooled Analysis of the RAFFINE and SAKURA Registries ―
External Validation of the HELT-E<sub>2</sub>S<sub>2</sub> Score in Japanese Patients With Nonvalvular Atrial Fibrillation ― A Pooled Analysis of the RAFFINE and SAKURA Registries ― Open
The HELT-E2S2score demonstrated potential value for risk stratification, particularly in a super-aged society such as Japan. However, its superiority over the CHADS2or CHA2DS2-VASc sco…
View article: Ultrasound stimulation of the vagal nerve improves acute septic encephalopathy in mice
Ultrasound stimulation of the vagal nerve improves acute septic encephalopathy in mice Open
Septic encephalopathy (SE) is characterized by symptoms such as coma, delirium, and cognitive dysfunction, and effective therapeutic interventions for SE remain elusive. In this study, we aimed to investigate the potential alleviating effe…
View article: Major bleeding increases the risk of subsequent cardiovascular events in patients with atrial fibrillation: Insights from the SAKURA AF registry and RAFFINE registry
Major bleeding increases the risk of subsequent cardiovascular events in patients with atrial fibrillation: Insights from the SAKURA AF registry and RAFFINE registry Open
Background Bleeding events are one of the major concerns in patients using oral anticoagulants (OACs). We aimed to evaluate the association between major bleeding and long-term clinical outcomes in atrial fibrillation (AF) patients taking …
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Table of Contents Open
View article: PO-02-088 CHANGES IN EPICARDIAL ADIPOSE TISSUE AND LEFT ATRIAL WALL SUBSTRATE AFTER ABLATION FOR ATRIAL FIBRILLATION
PO-02-088 CHANGES IN EPICARDIAL ADIPOSE TISSUE AND LEFT ATRIAL WALL SUBSTRATE AFTER ABLATION FOR ATRIAL FIBRILLATION Open
View article: AB-453070-1 NOVEL INSIGHTS OF GANGLIONATED PLEXI ABLATION FOR ATRIAL FIBRILLATION: FINDINGS FROM RECURRENCE CASES
AB-453070-1 NOVEL INSIGHTS OF GANGLIONATED PLEXI ABLATION FOR ATRIAL FIBRILLATION: FINDINGS FROM RECURRENCE CASES Open
View article: Massive left atrial calcification
Massive left atrial calcification Open
We reported this case because calcification of the mitral valve is a common complication of rheumatic fever, but calcification of the left atrium is rare.
View article: Collaboration of People and Society
Collaboration of People and Society Open
View article: Progress of <sup>18</sup>F-flurpiridaz in Clinical Trials
Progress of <sup>18</sup>F-flurpiridaz in Clinical Trials Open
18F-flurpiridaz is a novel positron emission computed tomography (PET) tracer in ongoing clinical trials in United States and Japan. A phase III prospective, open-label, multi-center study to assess the feasibility of 18
View article: Optimization of <sup>201</sup>Tl Dosage in a Simultaneous Acquisition Rest <sup>99m</sup>Tc/Stress <sup>201</sup>Tl Dual-Isotope Myocardial Perfusion Single-Photon Emission Computed Tomography with Semiconductor Gamma Camera
Optimization of <sup>201</sup>Tl Dosage in a Simultaneous Acquisition Rest <sup>99m</sup>Tc/Stress <sup>201</sup>Tl Dual-Isotope Myocardial Perfusion Single-Photon Emission Computed Tomography with Semiconductor Gamma Camera Open
Background: The use of 201Tl in myocardial perfusion single-photon emission computed tomography (SPECT) is predominantly not recommended because of the higher radiation exposure of 201Tl compared to 99m
View article: A study on Impact Absorbing Performance of CFRP Crash Box
A study on Impact Absorbing Performance of CFRP Crash Box Open
View article: Phase II Trial of the Combination of Alectinib with Bevacizumab in Alectinib Refractory ALK-Positive Nonsquamous Non-Small-Cell Lung Cancer (NLCTG1501)
Phase II Trial of the Combination of Alectinib with Bevacizumab in Alectinib Refractory ALK-Positive Nonsquamous Non-Small-Cell Lung Cancer (NLCTG1501) Open
Anaplastic lymphoma kinase (ALK)-positive lung cancer is a rare cancer that occurs in approximately 5% of non-small-cell lung cancer (NSCLCs) patients. Despite the excellent efficacy of ALK-tyrosine kinase inhibitor in ALK-positive NSCLCs,…
View article: Edoxaban Monotherapy in Nonvalvular Atrial Fibrillation Patients with Coronary Artery Disease
Edoxaban Monotherapy in Nonvalvular Atrial Fibrillation Patients with Coronary Artery Disease Open
Background. Current guidelines recommend an oral anticoagulant (OAC) monotherapy in patients with nonvalvular atrial fibrillation (NVAF) and stable coronary artery disease (CAD) 1 year postpercutaneous coronary intervention (PCI). It might…
View article: Effect of Catheter Ablation for Atrial Fibrillation in Heart Failure With Mid-Range or Preserved Ejection Fraction ― Pooled Analysis of the AF Frontier Ablation Registry and Hokuriku-Plus AF Registry ―
Effect of Catheter Ablation for Atrial Fibrillation in Heart Failure With Mid-Range or Preserved Ejection Fraction ― Pooled Analysis of the AF Frontier Ablation Registry and Hokuriku-Plus AF Registry ― Open
Compared with medical therapy, catheter ablation for AF in patients with heart failure and mid-range or preserved EF was associated with a significantly lower incidence of cardiovascular death or hospitalization for heart failure.
View article: Metronomic chemotherapy for pediatric refractory solid tumors: A retrospective single-center study
Metronomic chemotherapy for pediatric refractory solid tumors: A retrospective single-center study Open
Background: Metronomic chemotherapy (MC) is based on chronic administration of chemotherapeutic agents at minimally toxic doses without prolonged drug-free breaks. MC has a multitargeted action of tumor angiogenesis inhibition and anticanc…
View article: <scp>ST</scp> ‐elevation myocardial infarction after <scp>COVID</scp> ‐19 infection in a young man with Kawasaki disease
<span>ST</span> ‐elevation myocardial infarction after <span>COVID</span> ‐19 infection in a young man with Kawasaki disease Open
A 22‐year‐old male with a history of Kawasaki disease was admitted to our emergency department with an inferior ST elevation myocardial infarction (STEMI). He was infected with COVID‐19 one month prior to admission, and thereafter, stopped…
View article: Inadequate sleep duration may attenuate the anti-inflammatory effects of fish consumption in a healthy Japanese population: a cross-sectional study
Inadequate sleep duration may attenuate the anti-inflammatory effects of fish consumption in a healthy Japanese population: a cross-sectional study Open
High fish consumption may be associated with lower inflammation, suppressing atherosclerotic CVD (ASCVD). Long sleep duration, as well as short sleep, may contribute to inflammation, thus facilitating ASCVD. This study investigated the ove…
View article: Efficacy and safety of amrubicin therapy after chemoimmunotherapy in small cell lung cancer patients
Efficacy and safety of amrubicin therapy after chemoimmunotherapy in small cell lung cancer patients Open
AMR after chemoimmunotherapy shows good clinical efficacy and safety in patients with recurrent SCLC.