Naoya Tanabe
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View article: Consolidation-to-ground-glass opacity ratio on chest CT as a prognostic marker for critical outcomes in COVID-19: a retrospective cohort study
Consolidation-to-ground-glass opacity ratio on chest CT as a prognostic marker for critical outcomes in COVID-19: a retrospective cohort study Open
View article: Airway Mucus Plugs in <scp>COPD</scp> : A Potential Treatable Trait
Airway Mucus Plugs in <span>COPD</span> : A Potential Treatable Trait Open
View article: Comprehensive quantitation of bronchial and lung parenchymal lesions in idiopathic pleuroparenchymal fibroelastosis
Comprehensive quantitation of bronchial and lung parenchymal lesions in idiopathic pleuroparenchymal fibroelastosis Open
Quantitative chest CT analysis in IPPFE revealed that intrapulmonary bronchial volume was associated with prognosis and increased with disease progression.
View article: Superior performance of three-dimensional to two-dimensional convolutional neural network for predicting airflow limitation in patients with chronic obstructive pulmonary disease
Superior performance of three-dimensional to two-dimensional convolutional neural network for predicting airflow limitation in patients with chronic obstructive pulmonary disease Open
Volumetric analysis using 3D-CNN may sufficiently capture the complex structural features of COPD in CT images. Further studies are required to validate these models with larger datasets and determine their validity for longitudinal applic…
View article: Extent of pulmonary involvement on admission predicts long-term pulmonary and muscular sequelae of COVID-19: A longitudinal computed tomography study
Extent of pulmonary involvement on admission predicts long-term pulmonary and muscular sequelae of COVID-19: A longitudinal computed tomography study Open
CT-based quantification of pneumonia extent during the acute phase of COVID-19 may be useful in predicting long-term pulmonary sequelae and muscle wasting. This approach may allow the objective evaluation of Long COVID and facilitate the i…
View article: Correction: Computed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis
Correction: Computed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis Open
View article: Clinical and pathophysiological roles of lower lobe–dominant mucus plugs on computed tomography in patients with asthma with and without bronchiectasis
Clinical and pathophysiological roles of lower lobe–dominant mucus plugs on computed tomography in patients with asthma with and without bronchiectasis Open
Lower lobe-dominant mucus plugs were associated with lower lung function and exacerbations in patients with asthma, irrespective of comorbid bronchiectasis. The spatial distribution of mucus plugs additionally to whole-lung mucus plug scor…
View article: High Airway‐To‐Vessel Volume Ratio and Visual Bronchiectasis Are Associated With Exacerbations in <scp>COPD</scp>
High Airway‐To‐Vessel Volume Ratio and Visual Bronchiectasis Are Associated With Exacerbations in <span>COPD</span> Open
Background and Objective The effects of the volume mismatch between the airway and lung vasculature on exacerbation in chronic obstructive pulmonary disease (COPD) is uncertain. We aimed to examine the association between an increased volu…
View article: Determinants of airway morphology in asthma: Inflammatory and noninflammatory factors
Determinants of airway morphology in asthma: Inflammatory and noninflammatory factors Open
BMI, asthma duration, sinusitis, and the presence of bronchiectasis are significant determinants of airway tree morphology in asthma, alongside inflammation and mucus plugs. Both inflammatory and noninflammatory biomarkers were associated …
View article: Management of <scp>COPD</scp> With Cardiovascular Risk in Asia: A Review by the Asian Pacific Society of Respirology <scp>COPD</scp> Assembly
Management of <span>COPD</span> With Cardiovascular Risk in Asia: A Review by the Asian Pacific Society of Respirology <span>COPD</span> Assembly Open
Chronic obstructive pulmonary disease (COPD) has a high burden in Asia. These patients are also susceptible to various cardiovascular diseases (CVD). A panel of expert Asian pulmonologists explored the published literature to understand th…
View article: Potential Protective Role of Galectin‐3 in Airway Dilatation in Obstructive Airway Diseases
Potential Protective Role of Galectin‐3 in Airway Dilatation in Obstructive Airway Diseases Open
View article: From mucus plugging to airway dilatation in chronic airway diseases: A perspective on the contribution of the airway microbiome and inflammation
From mucus plugging to airway dilatation in chronic airway diseases: A perspective on the contribution of the airway microbiome and inflammation Open
Airway mucus plugs are the main pathological and computed tomography (CT) findings that affect clinical outcomes in patients with asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap. Despite the introduction of bi…
View article: Impact of excessive body fat mass on mortality after lung transplantation
Impact of excessive body fat mass on mortality after lung transplantation Open
After lung transplantation, the patients had increased BMI, FFMI, and FMI. The FMI increased above the reference values in an increasing number of patients, and a high FMI at 1 year post-transplantation was associated with a poor prognosis.
View article: Uneven distribution of air trapping and its impact on physical activity in patients with asthma
Uneven distribution of air trapping and its impact on physical activity in patients with asthma Open
The uneven distribution of air trapping in the lungs of patients with asthma, particularly in the upper lobe, was linked to reduced moderate-to-vigorous-intensity physical activity and was partially attributable to small airway obstruction…
View article: Exploring factors associated with clinical remission in patients with severe asthma receiving anti-IL-4Rα, anti-IL-5/5R, or anti-IgE treatment
Exploring factors associated with clinical remission in patients with severe asthma receiving anti-IL-4Rα, anti-IL-5/5R, or anti-IgE treatment Open
Anti-IL-4Rα treatment may be effective for patients with severe asthma who have chronic rhinosinusitis or high FeNO levels at baseline.
View article: Response to: Pneumatosis Intestinalis Induced by Nintedanib?
Response to: Pneumatosis Intestinalis Induced by Nintedanib? Open
View article: Importance of sputum and computed tomography assessments of airway neutrophil inflammation and mucus plugging in bronchiectasis management
Importance of sputum and computed tomography assessments of airway neutrophil inflammation and mucus plugging in bronchiectasis management Open
Sputum myeloperoxidase quantification and computed tomography scoring of mucus plugs in central airways deepen understanding of relationships between airway neutrophilic inflammation, mucus plugging and disease severity in patients with…
View article: Exploring the pathophysiology of anemia in COPD: Insights from chest CT and longitudinal clinical data
Exploring the pathophysiology of anemia in COPD: Insights from chest CT and longitudinal clinical data Open
Anemia in COPD is a multifactorial comorbidity resulting in emphysema, decreased fat and muscle mass, and reduced BMD.
View article: Stationary Oxygen Concentrator with Built-in Respiratory Rate Monitor: Clinical Validation of Its Efficacy in Patients with Interstitial Lung Disease and Chronic Obstructive Pulmonary Disease
Stationary Oxygen Concentrator with Built-in Respiratory Rate Monitor: Clinical Validation of Its Efficacy in Patients with Interstitial Lung Disease and Chronic Obstructive Pulmonary Disease Open
Objective The respiratory rate (RR) can be monitored continuously using a HiSanso®i, a stationary oxygen concentrator with a built-in respiratory sensor. To examine the efficacy of this device, we compared its performance with t…
View article: Pneumatosis Intestinalis Induced by Nintedanib
Pneumatosis Intestinalis Induced by Nintedanib Open
View article: Kernel Conversion Improves the Correlation between the Extent of Emphysema and Clinical Parameters in Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study
Kernel Conversion Improves the Correlation between the Extent of Emphysema and Clinical Parameters in Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study Open
Background: Computed tomography (CT) scans are utilized to assess emphysema, a prominent phenotype of chronic obstructive pulmonary disease (COPD). Variability in CT protocols and equipment across hospitals can impact accuracy. This study …
View article: Trajectory of the arterial-alveolar oxygen gradient in COPD for a decade
Trajectory of the arterial-alveolar oxygen gradient in COPD for a decade Open
Background Chronic respiratory failure (CRF) is a critical complication in patients with chronic obstructive pulmonary disease (COPD) and is characterized by an increase in the arterial-alveolar oxygen gradient (A-aDO 2 ). The long-term tr…
View article: Erector Spinae Muscle to Epicardial Visceral Fat Ratio on Chest CT Predicts the Severity of Coronavirus Disease 2019
Erector Spinae Muscle to Epicardial Visceral Fat Ratio on Chest CT Predicts the Severity of Coronavirus Disease 2019 Open
Background Chest computed tomography (CT) is a valuable tool for diagnosing and predicting the severity of coronavirus disease 2019 (COVID‐19) and assessing extrapulmonary organs. Reduced muscle mass and visceral fat accumulation are impor…
View article: Diffusing capacity and alveolar attachments to small airways in smokers with and without COPD
Diffusing capacity and alveolar attachments to small airways in smokers with and without COPD Open
The number of alveolar attachments to the small airways correlates with D LCO in smokers, both with and without COPD. Early smoking-related lung pathology is reflected in impaired D LCO. https://b…
View article: Spirometry estimation of central airway dysanapsis on computed tomography in healthy subjects without active lung diseases
Spirometry estimation of central airway dysanapsis on computed tomography in healthy subjects without active lung diseases Open
The airway-to-lung size discrepancy on computed tomography (CT-assessed dysanapsis) highlights a lifelong risk for developing lung diseases. This study demonstrated that the spirometric index of the dysanapsis ratio can be used for estimat…
View article: Coronary Artery Calcification on Chest Computed Tomography as a Predictor of Cardiovascular Adverse Events in Patients With COVID-19 ― A Multicenter Retrospective Study in Japan ―
Coronary Artery Calcification on Chest Computed Tomography as a Predictor of Cardiovascular Adverse Events in Patients With COVID-19 ― A Multicenter Retrospective Study in Japan ― Open
Patients with COVID-19 and severe CAC had increased cardiovascular complications, and identifying cardiovascular and pulmonary findings on chest CT is essential. Measuring CAC via non-electrocardiogram-gated CT helps predict patient risk.
View article: Prognostic value of a composite physiologic index developed by adding bronchial and hyperlucent volumes quantified via artificial intelligence technology
Prognostic value of a composite physiologic index developed by adding bronchial and hyperlucent volumes quantified via artificial intelligence technology Open
View article: Exploring the roles of airway dipeptidyl peptidase 1 in obstructive airway disease
Exploring the roles of airway dipeptidyl peptidase 1 in obstructive airway disease Open
Background Dipeptidyl peptidase 1 (DPP1) exacerbates airway neutrophilic inflammation in bronchiectasis, which is characterised by airway dysfunction and dilation and chronic bacterial infection. However, little is known about the pathogen…
View article: Computed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis
Computed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis Open
Increased lumen area and wall thickening of the central airways may be involved in the pathogenesis of ILA and IPF, and wall thickening may affect the prognosis of patients with IPF.
View article: Refractory phenotype of Aspergillus-sensitized asthma with bronchiectasis and allergic bronchopulmonary aspergillosis
Refractory phenotype of Aspergillus-sensitized asthma with bronchiectasis and allergic bronchopulmonary aspergillosis Open