Explanipedia

Microsurgical Robotic System for Myringoplasty: Feasibility Study Open

Tadao Yoshida, Masumi Kobayashi, T Okubo, Naoyuki Hatayama, Shun Otsuka , et al. · 2025

Objective Otological surgery requires exceptional precision and advanced surgical skills, particularly for procedures involving the tympanic membrane and middle ear structures. Microsurgical robotic systems have shown promise in enhancing …

The Impact of a Short-term High-fat Diet on Coagulation Function in a Mouse Model and Its Role in Exacerbating Concanavalin A-Induced Liver Injury Open

Eri Nanizawa, Yuki Tamaki, Tomiko Yakura, Shun Otsuka, Naoyuki Hatayama , et al. · 2024

Background Recently, the number of patients with non-alcoholic fatty liver disease (NAFLD) and its more advanced condition, non-alcoholic steatohepatitis (NASH), has been increasing. These patients are at a higher risk of cardiovascular ev…

Bridging the Gap: Advances and Challenges in Heart Regeneration from In Vitro to In Vivo Applications Open

Tatsuya Watanabe, Naoyuki Hatayama, Marissa Guo, Satoshi Yuhara, Toshiharu Shinoka · 2024

Cardiovascular diseases, particularly ischemic heart disease, area leading cause of morbidity and mortality worldwide. Myocardial infarction (MI) results in extensive cardiomyocyte loss, inflammation, extracellular matrix (ECM) degradation…

Neglected Sprengel’s deformity in an 80-year-old female cadaver: a case report Open

Shun Otsuka, Yuki Tamaki, Masaki Matsushita, Naoyuki Hatayama, Munekazu Naito · 2024

Role of endothelial hyaluronan in peritoneal membrane transport and disease conditions during peritoneal dialysis Open

Keisuke Kamiya, Naoyuki Hatayama, Mitsuhiro Tawada, Akimasa Asai, Mai Yamauchi , et al. · 2024

Peritoneal membrane dysfunction in peritoneal dialysis (PD) is primarily attributed to angiogenesis; however, the integrity of vascular endothelial cells can affect peritoneal permeability. Hyaluronan, a component of the endothelial glycoc…

A rat model for acute limb ischemia using microsized gelatin beads Open

Yuki Menjo, Masaya Yasui, Kaori Fukushige, Naoyuki Hatayama, Tomiko Yakura , et al. · 2024

Objective Acute limb ischemia (ALI) is a rapid decrease in lower limb blood flow due to acute occlusion of peripheral arteries or bypass grafts. This study aimed to establish an ALI model using microsized gelatin beads and to investigate t…

Role of endothelial hyaluronan in peritoneal membrane transport and disease conditions during peritoneal dialysis Open

Keisuke Kamiya, Naoyuki Hatayama, Mitsuhiro Tawada, Akimasa Asai, Mai Yamauchi , et al. · 2023

Peritoneal membrane dysfunction in peritoneal dialysis (PD) is primarily attributed to angiogenesis; however, the integrity of vascular endothelial cells can affect peritoneal permeability. Hyaluronan, a component of the endothelial glycoc…

Comparison of the decompressive effect of different surgical procedures for dysthyroid optic neuropathy using 3D printed models Open

Kinga Yo, Kunihiro Nishimura, Yasuhiro Takahashi, Hiroki Yokota, Naoyuki Hatayama , et al. · 2022

Purpose To compare the decompressive effect around the optic nerve canal among 3 different decompression procedures (medial, balanced, and inferomedial) using 3D printed models. Methods In this experimental study, based on data obtained fr…

Anorectal Transplantation: The First Long-term Success in a Canine Model. Open

Jun Araki, Yuji Nishizawa, Naoki Fujita, Tomoyuki Sato, Tomoya Iizuka , et al. · 2022

We describe the critical role of the pudendal nerve in anorectal function and the first long-term success with anorectal transplantation in a canine model. This report is a proof-of-concept study for anorectal transplantation as a treatmen…

Relationship Between Attachment Site of Tibialis Anterior Muscle and Shape of Tibia: Anatomical Study of Cadavers Open

Kentaro Kimata, Shun Otsuka, Hiroki Yokota, Xiyao Shan, Naoyuki Hatayama , et al. · 2022

Background: Tibialis anterior (TA) muscle is the largest dorsiflexor of the ankle joint and plays an important role during gait movement. However, descriptions of the TA attachment site are inconsistent even among major anatomy textbooks, …

Relationship between attachment site of tibialis anterior muscle and shape of tibia: anatomical study of cadavers Open

Kentaro Kimata, Shun Otsuka, Hiroki Yokota, Xiyao Shan, Naoyuki Hatayama , et al. · 2022

Background Tibialis anterior (TA) muscle is the largest dorsiflexor of the ankle joint and plays an important role during gait movement. However, descriptions of the TA attachment site are inconsistent even among major anatomy textbooks, a…

Roles of glomerular endothelial hyaluronan in the development of proteinuria Open

Akimasa Asai, Naoyuki Hatayama, Keisuke Kamiya, Mai Yamauchi, Hiroshi Kinashi , et al. · 2021

Vascular endothelial cells are covered with glycocalyx comprising heparan sulfate, hyaluronan, chondroitin sulfate, and associated proteins. Glomerular endothelial glycocalyx is involved in protecting against induction of proteinuria and s…

Anorectal Transplantation Open

Jun Araki, Yuji Nishizawa, Naoki Fujita, Tomoyuki Sato, Tomoya Lizuka , et al. · 2021

Objective: Anorectal transplantation is a challenging procedure but a promising option for patients with weakened or completely absent anorectal function. Summary Background Data: We constructed a canine model of anorectal transplantation,…

Cardioprotection via Metabolism for Rat Heart Preservation Using the High-Pressure Gaseous Mixture of Carbon Monoxide and Oxygen Open

Chiharu Suzuki, Naoyuki Hatayama, Tadashi Ogawa, Eri Nanizawa, Shun Otsuka , et al. · 2020

The high-pressure gas (HPG) method with carbon monoxide (CO) and oxygen (O2) mixture maintains the preserved rat heart function. The metabolites of rat hearts preserved using the HPG method (HPG group) and cold storage (CS) method (CS grou…

A rare third head of the biceps femoris in the posterior thigh Open

Reina Tsunekawa, Shuichi Hirai, Naoyuki Hatayama, Hiroki Yokota, Munekazu Naito , et al. · 2020

Anorectal Transplantation: The First Long-Term Success in a Canine Model Open

Jun Araki, Yuji Nishizawa, Naoki Fujita, Tomoyuki Sato, Tomoya Iizuka , et al. · 2020

A Part of the Medial Branch of the Deep Peroneal Nerve Distributes the Dorsal Pedis Artery and Its Distribution Area is Close to the Acupuncture Point LR3 (Taichong) Open

Kanae Umemoto, Munekazu Naito, Naoyuki Hatayama, Shuichi Hirai, Kou Sakabe · 2020

Cutaneous nerves have vascular branches (VBs) that reach the arteries and are thought to be involved in arterial constriction. We aimed to examine the anatomical and histological relationship between the VBs of a cutaneous nerve in the foo…

The effectiveness of traditional Japanese medicine Goshajinkigan in irradiation-induced aspermatogenesis in mice Open

Kumpei Takahashi, Kenta Nagahori, Ning Qu, Miyuki Kuramasu, Yoshie Hirayanagi , et al. · 2019

High-Pressure Carbon Monoxide and Oxygen Mixture is Effective for Lung Preservation Open

Atsushi Fujiwara, Naoyuki Hatayama, Natsumi Matsuura, Naoya Yokota, Kaori Fukushige , et al. · 2019

(1) Background: Heme oxygenase-1 (HO-1) degrades heme and generates carbon monoxide (CO), producing various anti-inflammatory, anti-oxidative, and anti-apoptotic effects. This study aimed to confirm the effects of CO on the ischemia–reperf…

Different effects of partial pressure in a high-pressure gaseous mixture of carbon monoxide and oxygen for rat heart preservation Open

Naoyuki Hatayama, Shuichi Hirai, Kaori Fukushige, Hiroki Yokota, Masahiro Itoh , et al. · 2019

We maintained the function of an extracted rat heart after 24–48 h preservation in a high-pressure gaseous mixture of carbon monoxide (CO) and oxygen (O 2 ). Here, we assessed the effects of different partial pressures of hyperbaric CO and…

Development of anatomical dynamic model of shoulder joint and surrounding tissue Open

Hiroki Yokota, Shigemichi OHSHIMA, Naoyuki Hatayama, Shuichi Hirai, Munekazu Naito · 2019

The shoulder joint represents the most unstable and complex structure in all of human joints. Shoulder movement involves complex interactions between skeletal system and soft tissues. Understanding these mechanical interactions is importan…

Preservation of rat limbs by hyperbaric carbon monoxide and oxygen Open

Naoyuki Hatayama, Shuichi Hirai, Munekazu Naito, Hayato Terayama, Jun Araki , et al. · 2018

Cold ischemia times ranging from <6 h to as long as 24 h are generally quoted as the limits for attempting the replantation of amputated extremities. In this study, we aimed to assess the effect of hyperbaric carbon monoxide (CO) and oxyge…

Wrist immobilization position contributing to stabilize a bone fracture fragment after a distal radius fracture Open

Hiroki Yokota, Masaya Yasui, Shuichi Hirai, Naoyuki Hatayama, Shigemichi OHSHIMA , et al. · 2018

Colles’ fracture is a common injury that tends to result in dorsal displacement of the bone fracture fragment of the distal radius. Most wrist fractures can be treated with closed reduction and wrist immobilization in a specific position t…

Pathological effect of arterial ischaemia and venous congestion on rat testes Open

Shuichi Hirai, Naoyuki Hatayama, Munekazu Naito, Kenta Nagahori, Shinichi Kawata , et al. · 2017

Development of heterotopic transplantation of the testis with the epididymis to evaluate an aspect of testicular immunology in rats Open

Kai Yi, Naoyuki Hatayama, Shuichi Hirai, Ning Qu, Shogo Hayashi , et al. · 2017

Transplantation of testicular cells and tissues has been studied for the investigation of immunology of the testis, which is an immunologically privileged organ. However, reports of transplant of the testis at organ level have been extreme…

High-pressure carbon monoxide preserves rat kidney grafts from apoptosis and inflammation Open

Toyofumi Abe, Koji Yazawa, Masayuki Fujino, Ryoichi Imamura, Naoyuki Hatayama , et al. · 2017

Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone Open

Hayato Terayama, Shuichi Hirai, Munekazu Naito, Ning Qu, Chiaki Katagiri , et al. · 2016

There are various autoimmunogenic antigens (AIs) in testicular germ cells (TGCs) recognized as foreign by the body’s immune system. However, there is little information of TGC-specific AIs being available. The aim of this study is to ident…

Functional evaluation of rat hearts transplanted after preservation in a high-pressure gaseous mixture of carbon monoxide and oxygen Open

Naoyuki Hatayama, Masayuki Inubushi, Munekazu Naito, Shuichi Hirai, Yong-Nan Jin , et al. · 2016

Anatomical structure of the subcutaneous tissue on the anterior surface of human thigh Open

Teruki ISHIDA, Kyoko Takeuchi, Shogo Hayashi, Shinichi Kawata, Naoyuki Hatayama , et al. · 2015

The anterior thighs of 16 limbs from eight donated cadavers were observed using ultrasonic imaging and gross dissection with a specific focus on the subcutaneous tissue, which is considered an auxiliary element of locomotion. On ultrasonic…

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