Nardeen Eldafashi
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View article: The Contribution of Innate Immune Cells to the Pathophysiology of Acute Sterile Inflammation- Evidence from Preclinical Animal Models
The Contribution of Innate Immune Cells to the Pathophysiology of Acute Sterile Inflammation- Evidence from Preclinical Animal Models Open
One of the most critical factors for managing patients with liver disease is inflammation. The liver mediates numerous functions in the innate immunity, these functions predispose the liver to immunity-mediated liver injury if this inflamm…
View article: Innate and Adaptive Immunopathogeneses in Viral Hepatitis; Crucial Determinants of Hepatocellular Carcinoma
Innate and Adaptive Immunopathogeneses in Viral Hepatitis; Crucial Determinants of Hepatocellular Carcinoma Open
Viral hepatitis B (HBV) and hepatitis C (HCV) infections remain the most common risk factors for the development of hepatocellular carcinoma (HCC), and their heterogeneous distribution influences the global prevalence of this common type o…
View article: A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC?
A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC? Open
Obesity and non-alcoholic fatty liver disease (NAFLD) are contributing to the global rise in deaths from hepatocellular carcinoma (HCC). The pathogenesis of NAFLD-HCC is not well understood. The severity of hepatic steatosis, steatohepatit…
View article: O7 Exploring genetic variation of PDCD1, which encodes T-cell receptor PD-1, in patients with non-alcoholic fatty liver disease (NAFLD) and hepatocellular carcinoma (HCC)
O7 Exploring genetic variation of PDCD1, which encodes T-cell receptor PD-1, in patients with non-alcoholic fatty liver disease (NAFLD) and hepatocellular carcinoma (HCC) Open
Background Within the common etiologies of chronic liver disease associated with HCC development, environmental and genetic factors contribute to individual susceptibility. Our focus was on NAFLD-HCC, where older age, male sex, diabetes an…