Explanipedia

Atraumatic Cervical Disc Herniation With Rapidly Progressive Myelopathy in a 47-Year-Old Male: A Case Report Open

B. C. Parker, Cody A. Cunningham, Abhijith Bathini, Naresh P. Patel, Wayne A Martini · 2024

Atraumatic acute myelopathy caused by idiopathic disc herniation is rare. This case presents a 47-year-old male with a sudden onset of severe neck pain and weakness upon waking that progressively worsened. His rapidly progressive myelopath…

Proton versus photon adjuvant radiotherapy: a multicenter comparative evaluation of recurrence following spinal chordoma resection Open

Abdul Karim Ghaith, Ruby H.N. Nguyen, Victor Gabriel El-Hajj, Alaa Montaser, Gaetano De Biase , et al. · 2024

OBJECTIVE Chordomas are rare tumors of the skull base and spine believed to arise from the vestiges of the embryonic notochord. These tumors are locally aggressive and frequently recur following resection and adjuvant radiotherapy. Proton …

Image-localized biopsy mapping of brain tumor heterogeneity: A single-center study protocol Open

Javier Urcuyo, Lee Curtin, Jazlynn Langworthy, Gustavo De León, Barrett J. Anderies , et al. · 2023

Brain cancers pose a novel set of difficulties due to the limited accessibility of human brain tumor tissue. For this reason, clinical decision-making relies heavily on MR imaging interpretation, yet the mapping between MRI features and un…

Durable responses at 24 months with high-frequency spinal cord stimulation for nonsurgical refractory back pain Open

Naresh P. Patel, Jessica Katz Jameson, Curtis A. Johnson, Daniel Kloster, Aaron Calodney , et al. · 2023

OBJECTIVE The objective of this study was to evaluate the 24-month durability of pain relief, function, quality of life, and safety outcomes for patients with nonsurgical refractory back pain (NSRBP) treated with high-frequency spinal cord…

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures Open

Leland Hu, Fulvio D’Angelo, Taylor M. Weiskittel, Francesca Pia Caruso, Shannon P. Fortin Ensign , et al. · 2023

Sampling restrictions have hindered the comprehensive study of invasive non-enhancing (NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present an integrated multi-omic analysis of spatially matched molecula…

Cryptography utilizing the Affine-Hill cipher and Extended Generalized Fibonacci matrices Open

Vaishali Billore, Naresh P. Patel · 2023

We are aware that a major cryptosystem element plays a crucial part in maintainingthe security and robustness of cryptography. Various researchers are focusing on creatingnew forms of cryptography and improving those that already exist usi…

Critical evaluation of functional neurosurgical fellowship program websites Open

Peter Gariscsak, Luisa F Figueredo, Rohin Singh, Henry O. Stonnington, Nolan J. Brown , et al. · 2023

Abstract Number ‐ 202: Multispecialty Involvement in Neuroendovascular Interventions Open

Nolan J. Brown, Kyle Steiger, Rohin Singh, Shane Shahrestani, Henry O. Stonnington , et al. · 2023

Introduction While neurovascular surgeries have largely been performed by neurosurgeons, the advent of endovascular procedures has produced increasing involvement of other specialists in this arena (i.e. neurologists and radiologists).This…

Abstract Number ‐ 201: Increased Utilization of Neuro‐Endovascular Procedures: 2013–2019 Open

Nolan J. Brown, Kyle Steiger, Rohin Singh, Stefan W. Koester, Shane Shahrestani , et al. · 2023

Introduction Endovascular procedures have become increasingly popular in recent years due to preference of minimally invasive approaches and technological advancement.This study aims to characterize the trends in procedural rates of common…

Clinical Outcomes of Stereotactic Radiosurgery-Related Radiation Necrosis in Patients with Intracranial Metastasis from Melanoma Open

Holly M Thomson, Shannon P. Fortin Ensign, Victoria S. Edmonds, Akanksha Sharma, Richard Butterfield , et al. · 2023

Background: Radiation necrosis (RN) is a clinically relevant complication of stereotactic radiosurgery (SRS) for intracranial metastasis (ICM) treatments. Radiation necrosis development is variable following SRS. It remains unclear if risk…

Image-localized biopsy mapping of brain tumor heterogeneity: A single-center study protocol Open

Javier Urcuyo, Lee Curtin, Jazlynn Langworthy, Gustavo De León, Barrett J. Anderies , et al. · 2022

Brain cancers pose a novel set of difficulties due to the limited accessibility of human brain tumor tissue. For this reason, clinical decision-making relies heavily on MR imaging interpretation, yet the mapping between MRI features and un…

Robotics in neurosurgery: Current prevalence and future directions Open

Rohin Singh, Kendra Wang, Muhammad B. Qureshi, India Rangel, Nolan J. Brown , et al. · 2022

Background: The first instance of a robotic-assisted surgery occurred in neurosurgery; however, it is now more common in other fields such as urology and gynecology. This study aims to characterize the prevalence of robotic surgery among c…

A brief human history of ankylosing spondylitis: A scoping review of pathogenesis, diagnosis, and treatment Open

Sierra Murphy, Brandon Nguyen, Rohin Singh, Nolan J. Brown, Shane Shahrestani , et al. · 2022

Background: Ankylosing spondylitis (AS) is a chronic, progressive, inflammatory disease of the spine and SI joints. Diagnostic criteria and treatments have continued to evolve, necessitating a historical compendium of AS and its management…

Surgical treatment of spinal cord compression due to Hirayama disease: illustrative case Open

Rohin Singh, Miles Hudson, Jenna H. Meyer, Matthew T. Neal, Naresh P. Patel · 2022

BACKGROUND Hirayama disease (HD), also known as juvenile spinal muscular atrophy, is a rare condition in which flexion of the cervical neck causes compression and ischemic changes to the anterior horns of the spinal cord. Here the authors …

Treatment of nonsurgical refractory back pain with high-frequency spinal cord stimulation at 10 kHz: 12-month results of a pragmatic, multicenter, randomized controlled trial Open

Leonardo Kapural, Jessica Jameson, Curtis D. Johnson, Daniel Kloster, Aaron Calodney , et al. · 2022

OBJECTIVE Spinal cord stimulation (SCS) at 10 kHz (10-kHz SCS) is a safe and effective therapy for treatment of chronic low-back pain. However, it is unclear from existing evidence whether these findings can be generalized to patients with…

Dysphagia Caused by Two Possible Culprits - Diverticulum or Osteophyte Open

Brian R. Walker, Naresh P. Patel, William E. Karle · 2021

Killian-Jamieson Diverticulum (KJD) is a rare and often misdiagnosed esophageal diverticulum with a wide variability of presentation and treatment options.We report the first case of KJD treated with cervical osteophytectomy in addition to…

Content and Functionality of United States Medical School Websites Open

Jordan R. Pollock, M. Lane Moore, Jacob F. Smith, Jonny B Woolstenhulme, Dane J. Markham , et al. · 2021

Surgical Management of Retro-Odontoid Cystic Mass with Cervicomedullary Compression Open

Mark Lyons, Matthew T. Neal, Maziyar A. Kalani, Naresh P. Patel · 2021

Retro-odontoid cysts are a rare cause of cervicomedullary compression. The etiology of these lesions is not completely understood. Previous trauma and instability at the cervicomedullary junction may be the precipitating event in the devel…

Carbon fiber–reinforced PEEK instrumentation in the spinal oncology population: a retrospective series demonstrating technique, feasibility, and clinical outcomes Open

Matthew T. Neal, Alexandra E. Richards, Kara L. Curley, Naresh P. Patel, Jonathan B. Ashman , et al. · 2021

OBJECTIVE The authors aimed to demonstrate the feasibility and advantages of carbon fiber–reinforced PEEK (CFRP) composite implants in patients with both primary and secondary osseous spinal tumors. METHODS Twenty-eight spinal tumor patien…

Functional recovery following surgery for chronic subdural hematoma Open

Sarah Merrill, Daniel Khan, Alexandra E. Richards, Maziyar A. Kalani, Naresh P. Patel , et al. · 2020

Background: Among the elderly, chronic subdural hematoma is a relatively common neurosurgical condition. Presenting symptoms range from headache and focal neurological deficits to seizure and coma depending on location and extent of brain …

Acute Spinal Cord Contusion in a Patient with Multiple Upper Cervical Fractures, Parkinson’s Disease, and Torticollis: Surgical Management Open

Sarah Merrill, Maziyar A. Kalani, Naresh P. Patel, Mark Lyons, Matthew T. Neal · 2020

Case Report . Spine surgery in patients with Parkinson’s disease (PD) involves increased risk. We describe a case of cervical myelopathy in a patient with PD, multiple fractures involving the atlas and axis vertebrae, and spasmodic tortico…

Surgical Management of Thoracic Osteomyelitis due to Escherichia Coli Sepsis Open

Mark Lyons, Maziyar A. Kalani, Matthew T. Neal, Naresh P. Patel · 2020

Case Report . Escherichia coli is a rare cause of vertebral osteomyelitis. It is more common in adults and males. We present a case of an immunocompetent adult male presenting with a several month history of progressive systemic symptoms a…

Return to Golf, Tennis, and Swimming After Elective Cervical Spine Surgery Open

Alexandra E. Richards, Andrew R. Pines, Nicholas Rubel, David J. Mauler, Joseph Farnsworth , et al. · 2020

Background After surgery for degenerative cervical spine problems, most patients hope to return to non-competitive sports and other leisure activities. Limited data are available to counsel patients about return to play (RTP) in non-compet…

High‐Frequency Spinal Cord Stimulation at 10 kHz for the Treatment of Nonsurgical Refractory Back Pain: Design of a Pragmatic, Multicenter, Randomized Controlled Trial Open

Naresh P. Patel, Aaron Calodney, Leonardo Kapural, Rose Province‐Azalde, Shivanand P. Lad , et al. · 2020

Background Spinal cord stimulation (SCS) has been shown to provide pain relief for chronic back and leg pain due to failed back surgery syndrome. But many patients with chronic back pain have not had major back surgery or are not good cand…

Images in Practice: Replacement of an 18-Year-Old Spinal Cord Stimulator Paddle Lead with Cylindrical Leads Under Direct Visualization Open

Philip M. Shumsky, Christopher Wie, John A. Freeman, Omar Viswanath, Naresh P. Patel · 2020

Oral Presentations from the 2020 AANS Annual Scientific Meeting Open

Alexandra Richards, Jodee Winter, Naresh P. Patel, Matthew T. Neal, Chandan Krishna , et al. · 2020

Introduction:Anterior lumbar interbody fusion (ALIF) is used to treat lumbar spondylosis and spondylolisthesis.The operation involves an anterior, retroperitoneal approach to the spine.Patients frequently experience a slow return of bowel …

CMET-05. EVALUATING RADIATION NECROSIS IN PATIENTS WITH INTRACRANIAL METASTASES FROM MELANOMA Open

Victoria S. Edmonds, Holly Thomson, Akanksha Sharma, Richard Butterfield, Nan Zhang , et al. · 2019

BACKGROUND Radiation is an integral component of the multidisciplinary treatment of patients with intracranial metastasis (ICM) from melanoma. The risk of radiation necrosis (RN) post-treatment can range from 5–25%. We retrospectively eval…

Progressive Back Pain due to<i>Aspergillus nidulans</i>Vertebral Osteomyelitis in an Immunocompetent Patient: Surgical and Antifungal Management Open

Mark Lyons, Matthew T. Neal, Naresh P. Patel, Holenarasipur R. Vikram · 2019

Case Report . Aspergillus osteomyelitis is a destructive and progressive infection that has been described both in immunosuppressed and in immunocompetent hosts. We describe a case of lumbar vertebral osteomyelitis in a 61-year-old immunoc…

Analysis of MRI Volumetric Changes After Hypofractionated Stereotactic Radiation Therapy for Benign Intracranial Neoplasms Open

K. Rebecca Fega, Geoffrey P. Fletcher, Mark R. Waddle, Jennifer Peterson, Jonathan B. Ashman , et al. · 2018

HABIB TANVIR: TUNING THE FOLK AND THE MODERN Open

Naresh P. Patel, Seema Bhupendra · 2017

Eminent playwright Habib Tanvir was one of the greatest stalwarts of the modern Indian stage who is known for blending folk theatre and poetry in his dramaturgy thus leaving an indelible mark on the minds of the common people. Folk music a…

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