Explanipedia

Electrochemical sensor doped with core-shell structured molecularly imprinted polymer proposed for therapeutic drug monitoring of trazodone hydrochloride Open

Amr M. Mahmoud, Nariman A. El‐Ragehy, Maha A. Hegazy, Samia A. Tawfik, Ghada A. Sedik · 2025

Currently, the global push for eco-friendly analytical techniques has altered the priorities of analytical methodologies in accordance with their level of adherence to the principles of green analytical chemistry. Herein, sustainable, sens…

Eco-friendly HPTLC Determination of Paracetamol, Caffeine, Drotaverine HCl and Two of their Official Impurities; Application to Assay and Content Uniformity Testing of Tablet Dosage Form Open

Samia A. Tawfik, Nariman A. El‐Ragehy, Maha A. Hegazy, Ghada A. Sedik · 2024

Smart chemometrics-assisted spectrophotometric methods for efficient resolution and simultaneous determination of paracetamol, caffeine, drotaverine HCl along with three of their corresponding related impurities Open

Samia A. Tawfik, Maha A. Hegazy, Nariman A. El‐Ragehy, Ghada A. Sedik · 2023

Thin layer chromatography‒spectrodensitometric determination of a three-component mixture of propyphenazone, caffeine, ergotamine tartrate, and two of their impurities with application to tablets, spiked human plasma, and green profile assessment Open

M. T. H. Ragab, Nesrin K. Ramadan, Nariman A. El‐Ragehy, Badr A. El‐Zeany · 2023

A novel, green, and cost-effective thin-layer chromatography (TLC)‒spectrodensitometric method was designed and validated for the simultaneous determination of a five-component mixture. The analyzed mixture is composed of three active ingr…

Validated chromatographic methods for the simultaneous determination of a ternary mixture of sulfacetamide sodium and two of its official impurities; sulfanilamide and dapsone Open

Nariman A. El‐Ragehy, Maha A. Hegazy, Samia A. Tawfik, Ghada A. Sedik · 2021

Sulfacetamide sodium is a widely prescribed sulfonamide drug due to its topical antibacterial action on eye and skin. Four impurities are stated in the British Pharmacopoeia among which are sulfanilamide and dapsone. This work presents two…

RP-HPLC Method for the Simultaneous Determination of a Quaternary Mixture of Propyphenazone, Flavoxate HCl and Two of Their Official Impurities with Dissolution Profiling of Their Tablets Open

Nariman A. El‐Ragehy, Nesrin K. Ramadan, M. T. Ragab, Badr A. El‐Zeany · 2020

Background Determination of different drugs in the presence of their impurities is now receiving attention from regulatory authorities such as the ICH and the United States Food and Drug Administration (USFDA). Objective To develop and val…

Validated potentiometric method for the determination of sulfacetamide sodium; application to its pharmaceutical formulations and spiked rabbit aqueous humor Open

Nariman A. El‐Ragehy, Maha A. Hegazy, G.H. Abdel-Hamid, Samia A. Tawfik · 2018

Specific, accurate and precise electrochemical method was developed and validated for the determination of sulfacetamide sodium in presence of its co-formulated drug (prednisolone acetate) and its pharmacopoeial impurities. The method was …

Validated Chromatographic Methods for the Simultaneous Determination of Sulfacetamide Sodium and Prednisolone Acetate in their Ophthalmic Suspension Open

Nariman A. El‐Ragehy, Maha A. Hegazy, G.H. Abdel-Hamid, Samia A. Tawfik · 2017

Two specific, sensitive, rapid and accurate chromatographic methods have been developed, optimized and validated for the simultaneous determination of sulfacetamide sodium and prednisolone acetate in pure forms and in their binary mixture.…

Simultaneous Determination of Aspirin, Dipyridamole and Two of Their Related Impurities in Capsules by Validated TLC-Densitometric and HPLC Methods Open

Nariman A. El‐Ragehy, Nagiba Y. Hassan, Mahmoud A. Tantawy, M. A. Abdelkawy · 2016

Aspirin (ASP) and dipyridamole (DIP) are widely used as a combination in pharmaceutical formulations for treatment of strokes. Many of these formulations are containing tartaric acid as an excipient (in DIP pellets formulation for sustaine…

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