Natale Vincenzo Maiorana
YOU?
Author Swipe
View article: Electric Field-Induced Destabilization and Surface Modulation of Aβ42 Fibrils in Molecular Simulations: Theoretical Implications for DC Stimulation in Alzheimer’s Disease
Electric Field-Induced Destabilization and Surface Modulation of Aβ42 Fibrils in Molecular Simulations: Theoretical Implications for DC Stimulation in Alzheimer’s Disease Open
The amyloid-β peptide 42 (Aβ42) forms fibrillar aggregates that are a hallmark of Alzheimer’s disease. While recent pharmacologic therapeutic strategies targeting Aβ42 fibrils and oligomers have shown promising results, safer and more effe…
View article: Cognitive effects of adaptive deep brain stimulation in Parkinson’s disease: stability without risk
Cognitive effects of adaptive deep brain stimulation in Parkinson’s disease: stability without risk Open
View article: Direct Current (DC)-induced modulation of lipid metabolism and intercellular vesicular trafficking on a neuroblastoma in vitro model: implications for Parkinson’s disease
Direct Current (DC)-induced modulation of lipid metabolism and intercellular vesicular trafficking on a neuroblastoma in vitro model: implications for Parkinson’s disease Open
View article: Large Language Models in Neurological Practice: Real-World Study
Large Language Models in Neurological Practice: Real-World Study Open
Background Large language models (LLMs) such as ChatGPT (OpenAI) and Gemini (Google) are increasingly explored for their potential in medical diagnostics, including neurology. Their real-world applicability remains inadequately assessed, p…
View article: Cognitive Effects of Adaptive Deep Brain Stimulation in Parkinson’s Disease: Stability Without Risk
Cognitive Effects of Adaptive Deep Brain Stimulation in Parkinson’s Disease: Stability Without Risk Open
Background Adaptive deep brain stimulation (aDBS) is a closed-loop system that adjusts stimulation based on patient biomarkers. This study evaluated the cognitive safety of aDBS in Parkinson’s disease (PD). Methods Seventeen PD patients wi…
View article: Will adaptive deep brain stimulation for Parkinson’s disease become a real option soon? A Delphi consensus study
Will adaptive deep brain stimulation for Parkinson’s disease become a real option soon? A Delphi consensus study Open
While conventional deep brain stimulation (cDBS) treatment delivers continuous electrical stimuli, new adaptive DBS (aDBS) technology provides dynamic symptom-related stimulation. Research data are promising, and devices are already availa…
View article: Is physical therapy recommended for people with parkinson’s disease treated with subthalamic deep brain stimulation? a delphi consensus study
Is physical therapy recommended for people with parkinson’s disease treated with subthalamic deep brain stimulation? a delphi consensus study Open
View article: The “Cocombola Study”: A Physical Phantom Model for tDCS-Induced Electric Field Distribution
The “Cocombola Study”: A Physical Phantom Model for tDCS-Induced Electric Field Distribution Open
Background: Transcranial direct current stimulation (tDCS)-induced electric fields (EFs) acting on brain tissues are hardly controllable. Among physical models used in neuroscience research, watermelons are known as head-like phantoms for …
View article: Is it time for the neurologist to use Large Language Models in everyday practice? (Preprint)
Is it time for the neurologist to use Large Language Models in everyday practice? (Preprint) Open
BACKGROUND Large Language Models (LLMs) such as ChatGPT and Gemini are increasingly explored for their potential in medical diagnostics, including neurology. Their real-world applicability remains inadequately assessed, particularly in cl…
View article: Direct Current Stimulation ( <scp>DCS</scp> ) Modulates Lipid Metabolism and Intercellular Vesicular Trafficking in SHSY‐5Y Cell Line: Implications for Parkinson's Disease
Direct Current Stimulation ( <span>DCS</span> ) Modulates Lipid Metabolism and Intercellular Vesicular Trafficking in SHSY‐5Y Cell Line: Implications for Parkinson's Disease Open
The modulation of the brain's electrical activity for therapeutic purposes has recently gained attention, supported by the promising results obtained through the non‐invasive application of transcranial direct current stimulation (tDCS) in…
View article: Is it time for the neurologist to use Large Language Models in everyday practice?
Is it time for the neurologist to use Large Language Models in everyday practice? Open
Large Language Models (LLMs) such as ChatGPT and Gemini are gaining momentum in healthcare for their diagnostic potential. However, their real-world applicability in specialized medical fields like neurology remains inadequately explored. …
View article: Invasive and Non-Invasive Brain Stimulation: Neuroprotection, Lysosomal Pathways, and a Novel Invertebrate Model for Neurodegenerative Research
Invasive and Non-Invasive Brain Stimulation: Neuroprotection, Lysosomal Pathways, and a Novel Invertebrate Model for Neurodegenerative Research Open
View article: Direct current stimulation modulates lipid metabolism, neuroplasticity and intercellular communication
Direct current stimulation modulates lipid metabolism, neuroplasticity and intercellular communication Open
View article: Physical therapy in patients with Parkinson’s disease treated with Deep Brain Stimulation: a Delphi panel study
Physical therapy in patients with Parkinson’s disease treated with Deep Brain Stimulation: a Delphi panel study Open
Although deep brain stimulation of the subthalamic nucleus (STN-DBS) induces motor benefits in people with Parkinson’s disease (PwPD), the size and duration of the effects of STN-DBS on motor axial (e.g., postural instability, trunk postur…
View article: ‘Knock down the brain’: a nonlinear analysis of electroencephalography to study the effects of sub‐concussion in boxers
‘Knock down the brain’: a nonlinear analysis of electroencephalography to study the effects of sub‐concussion in boxers Open
Background and purpose Boxing is associated with a high risk of head injuries and increases the likelihood of chronic traumatic encephalopathy. This study explores the effects of sub‐concussive impacts on boxers by applying both linear and…
View article: Adaptive Deep Brain Stimulation in Parkinson’s Disease: A Delphi Consensus Study
Adaptive Deep Brain Stimulation in Parkinson’s Disease: A Delphi Consensus Study Open
Importance If history teaches, as cardiac pacing moved from fixed-rate to on-demand delivery in in 80s of the last century, there are high probabilities that closed-loop and adaptive approaches will become, in the next decade, the natural …
View article: Lessons on neurodegeneration and aging from the Lagoon of Venice: the marine invertebrate <i>Botryllus schlosseri</i>
Lessons on neurodegeneration and aging from the Lagoon of Venice: the marine invertebrate <i>Botryllus schlosseri</i> Open
In this work, the authors proposed a novel and interesting animal model for studying human neurodegenerative diseases, Botryllus schlosseri, a small invertebrate inhabiting temperate seas worldwide, which shares remarkable similarities wit…
View article: Monopolar tDCS might affect brainstem reflexes: A computational and neurophysiological study
Monopolar tDCS might affect brainstem reflexes: A computational and neurophysiological study Open
Multi-electrode tDCS (anodes over motor cortices, cathode over right deltoid) might be further explored to affect brainstem activity, also in the context of non-invasive deep brain stimulation.
View article: Modeling Electric Fields in Transcutaneous Spinal Direct Current Stimulation: A Clinical Perspective
Modeling Electric Fields in Transcutaneous Spinal Direct Current Stimulation: A Clinical Perspective Open
Clinical findings suggest that transcutaneous spinal direct current stimulation (tsDCS) can modulate ascending sensitive, descending corticospinal, and segmental pathways in the spinal cord (SC). However, several aspects of the stimulation…
View article: Monopolar transcranial direct current stimulation (tDCS) might selectively affect brainstem reflex pathways: a computational and neurophysiological study.
Monopolar transcranial direct current stimulation (tDCS) might selectively affect brainstem reflex pathways: a computational and neurophysiological study. Open
Non-invasive deep brain stimulation is a novel field of research that aims to affect deep brain regions’ activity through non-invasive stimulation. Recent computational and clinical findings have fostered the interest on transcranial direc…
View article: The Effects of a New Integrated and Multidisciplinary Cognitive Rehabilitation Program Based on Mindfulness and Reminiscence Therapy in Patients with Parkinson’s Disease and Mild Cognitive Impairment: A Pilot Study
The Effects of a New Integrated and Multidisciplinary Cognitive Rehabilitation Program Based on Mindfulness and Reminiscence Therapy in Patients with Parkinson’s Disease and Mild Cognitive Impairment: A Pilot Study Open
Background: Mindfulness trainings have shown promising results as treatment for behavioural symptoms in several pathologies. In addition, mindfulness protocols induced an improvement in memory and attention. Therefore, mindfulness could be…
View article: Brain positron emission tomography (PET) and cognitive abnormalities one year after COVID-19
Brain positron emission tomography (PET) and cognitive abnormalities one year after COVID-19 Open
View article: Relationship between Reaction Times and Post-COVID-19 Symptoms Assessed by a Web-Based Visual Detection Task
Relationship between Reaction Times and Post-COVID-19 Symptoms Assessed by a Web-Based Visual Detection Task Open
Long-COVID is a clinical condition in which patients affected by SARS-CoV-2 usually report a wide range of physical and cognitive symptoms from 3 to 6 months after the infection recovery. The aim of the current study was to assess the link…
View article: Effects of Cerebellar Transcranial Direct Current Stimulation on shape recognition and mental rotation
Effects of Cerebellar Transcranial Direct Current Stimulation on shape recognition and mental rotation Open
View article: Modelling novel tDCS settings for interfering with the brainstem activity
Modelling novel tDCS settings for interfering with the brainstem activity Open
View article: Emotional and autonomic response to visual erotic stimulation in patients with functional hypothalamic amenorrhea
Emotional and autonomic response to visual erotic stimulation in patients with functional hypothalamic amenorrhea Open
Introduction Functional hypothalamic amenorrhea (FHA) is a clinical condition associated with high levels of physiological and psychological stress ranging from weight loss to maladaptive behavior and coping skills. A reliable measure of t…
View article: Simultaneous Bilateral Frontal and Bilateral Cerebellar Transcranial Direct Current Stimulation in Treatment-Resistant Depression—Clinical Effects and Electrical Field Modelling of a Novel Electrodes Montage
Simultaneous Bilateral Frontal and Bilateral Cerebellar Transcranial Direct Current Stimulation in Treatment-Resistant Depression—Clinical Effects and Electrical Field Modelling of a Novel Electrodes Montage Open
Depressive disorders are one of the leading causes of disability worldwide. Transcranial direct current stimulation (tDCS) is a safe, simple, non-invasive brain stimulation technique showing considerable effectiveness in improving depressi…
View article: The Effect of Surgical Masks on the Featural and Configural Processing of Emotions
The Effect of Surgical Masks on the Featural and Configural Processing of Emotions Open
From the start of the COVID-19 pandemic, the use of surgical masks became widespread. However, they occlude an important part of the face and make it difficult to decode and interpret other people’s emotions. To clarify the effect of surgi…
View article: Effects of cerebellar tDCS on glycometabolic control
Effects of cerebellar tDCS on glycometabolic control Open
View article: Electric field distribution in deep brain structures during transcranial direct current stimulation (tDCS) with extracephalic montages: a computational study
Electric field distribution in deep brain structures during transcranial direct current stimulation (tDCS) with extracephalic montages: a computational study Open
developed individual MRI-driven computational head model.This study was aimed to evaluate the inter-rater reliability of the anatomical landmarks in the computational head models.Twenty brain MR images were reconstructed with computational…