Natalia Han
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View article: Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments
Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments Open
Objective This study examined real-world treatment patterns and outcomes in patients with melanoma brain metastasis (MBM) treated with first-line immunotherapy consisting of nivolumab plus ipilimumab or anti-programmed death-1 (PD-1) monot…
View article: Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes Open
Progressive supranuclear palsy (PSP), a rare Parkinsonian disorder, is characterized by problems with movement, balance, and cognition. PSP differs from Alzheimer's disease (AD) and other diseases, displaying abnormal microtubule-associate…
View article: Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes Open
Progressive supranuclear palsy (PSP) is a rare Parkinsonian disorder characterized by problems with movement, balance, cognition, and other symptoms. PSP differs from Alzheimer’s disease (AD) and other neurodegenerative diseases displaying…
View article: Genome-wide association study and functional validation implicates JADE1 in tauopathy
Genome-wide association study and functional validation implicates JADE1 in tauopathy Open
Primary age-related tauopathy (PART) is a neurodegenerative pathology with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amne…
View article: Genome-wide association study and functional validation implicates JADE1 in tauopathy
Genome-wide association study and functional validation implicates JADE1 in tauopathy Open
Primary age-related tauopathy (PART) is a neurodegenerative tauopathy with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amne…
View article: Toys with Wings: Creating Value through Collaborative Entrepreneurial Mindset Learning
Toys with Wings: Creating Value through Collaborative Entrepreneurial Mindset Learning Open
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View article: P1‐144: GENOME‐WIDE ASSOCIATION STUDY IN AN AUTOPSY COHORT OF PROGRESSIVE SUPRANUCLEAR PALSY
P1‐144: GENOME‐WIDE ASSOCIATION STUDY IN AN AUTOPSY COHORT OF PROGRESSIVE SUPRANUCLEAR PALSY Open
Progressive supranuclear palsy (PSP) is a prototype primary tauopathy and movement disorder. Previous genome wide association studies have revealed a strong genetic risk conferred by the MAPT 17q.21.31 locus as well as candidate risk allel…
View article: P4‐065: CLINICOPATHOLOGICAL CORRELATIONS IN PRIMARY AGE‐RELATED TAUOPATHY
P4‐065: CLINICOPATHOLOGICAL CORRELATIONS IN PRIMARY AGE‐RELATED TAUOPATHY Open
Recent studies had defined a distinct category of Alzheimer's type neurofibrillary degeneration that occurs in the absence of amyloid pathology. While tau pathology in Alzheimer's disease (AD) develops first in the medial temporal lobe and…