Natalia M. Weinzierl
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View article: Vincristine impairs musculoskeletal development in pediatric mice
Vincristine impairs musculoskeletal development in pediatric mice Open
View article: Vincristine impairs musculoskeletal development in pediatric mice
Vincristine impairs musculoskeletal development in pediatric mice Open
View article: Sex-specific survival but not tissue wasting in the KPP mouse model of pancreatic cancer-induced cachexia
Sex-specific survival but not tissue wasting in the KPP mouse model of pancreatic cancer-induced cachexia Open
Although male mice experience greater relative body weight losses, similar skeletal muscle and adipose tissue wasting occurs between male and female mice in the Kras LSL-G12D , Ptf1a Cre-ER/+ , Pten flox/flox (KPP) model of pancreatic-canc…
View article: B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer
B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer Open
This study introduces a novel preclinical model for head and neck cancer (HNC) cachexia using B0092 oral squamous cell carcinoma in C57BL/6J mice. Key findings include muscle atrophy, systemic musculoskeletal effects, and critical gene sig…
View article: Sex-specific survival but not tissue wasting in the KPP mouse model of pancreatic cancer-induced cachexia
Sex-specific survival but not tissue wasting in the KPP mouse model of pancreatic cancer-induced cachexia Open
Cancer cachexia, a multifactorial condition resulting in muscle and adipose tissue wasting, reduces the quality of life of many people with cancer. Despite decades of research, therapeutic options for cancer cachexia remain limited. Cachex…
View article: Diversity in chemotherapy-induced cachexia
Diversity in chemotherapy-induced cachexia Open
Preclinical and clinical studies suggest that chronic administration of cytotoxic drugs (e.g., chemotherapy) may contribute to the occurrence of skeletal muscle wasting and weakness/fatigue (i.e., cachexia). Doxorubicin, folfiri, and cispl…