Nathalie A. Compagnone
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View article: Plant Polyprenols Disrupt the IP3R-GRP75-VDAC-MCU Axis to Restore Mitochondrial Motility Defects Associated with Alzheimer’s Disease
Plant Polyprenols Disrupt the IP3R-GRP75-VDAC-MCU Axis to Restore Mitochondrial Motility Defects Associated with Alzheimer’s Disease Open
Standardized Plant Polyprenols (SPP) were shown to ameliorate cognitive function in a rat model of Alzheimer’s Disease (AD) but we lack understanding of its mechanism of action. The increasing prevalence of AD with age makes it a major hea…
View article: ANT1 overexpression models: Some similarities with facioscapulohumeral muscular dystrophy
ANT1 overexpression models: Some similarities with facioscapulohumeral muscular dystrophy Open
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disorder characterized by progressive muscle weakness. Adenine nucleotide translocator 1 (ANT1), the only 4q35 gene involved in mitochondrial function, is strongly expr…
View article: Effect of Red <i>Panax ginseng</i> on Mitochondrial Dynamics and Bioenergetics in HaCaT Cells Exposed to Urban Pollutants
Effect of Red <i>Panax ginseng</i> on Mitochondrial Dynamics and Bioenergetics in HaCaT Cells Exposed to Urban Pollutants Open
Background: Urban air pollution contributes to lung and cardiovascular system dysfunction, making it a major concern for human health. Its impact on skin integrity, associated with increased occurrence of atopic dermatitis, is now recogniz…
View article: [P3–214]: ADFLAG<sup>®</sup>, A DIAGNOSTIC BLOOD TEST FOR PRE‐DEMENTIA STAGES OF ALZHEIMER's DISEASE
[P3–214]: ADFLAG<sup>®</sup>, A DIAGNOSTIC BLOOD TEST FOR PRE‐DEMENTIA STAGES OF ALZHEIMER's DISEASE Open
Alzheimer's disease (AD) affects 47.5 million people worldwide1. Despite significant efforts, no treatments are available due to decades of failure in DMD development. One of the reasons for these failures lies in the lack of efficient pat…