Nathan Bouk
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The NCBI Comparative Genome Viewer (CGV) is an interactive visualization tool for the analysis of whole-genome eukaryotic alignments Open
We report a new visualization tool for analysis of whole-genome assembly-assembly alignments, the Comparative Genome Viewer (CGV) ( https://ncbi.nlm.nih.gov/genome/cgv/ ). CGV visualizes pairwise same-species and cross-species alignments p…
Rapid and sensitive detection of genome contamination at scale with FCS-GX Open
Assembled genome sequences are being generated at an exponential rate. Here we present FCS-GX, part of NCBI’s Foreign Contamination Screen (FCS) tool suite, optimized to identify and remove contaminant sequences in new genomes. FCS-GX scre…
Interactive visualization of whole eukaryote genome alignments using NCBI’s Comparative Genome Viewer (CGV) Open
We report a new visualization tool for analysis of whole genome assembly-assembly alignments, the Comparative Genome Viewer (CGV) ( https://ncbi.nlm.nih.gov/genome/cgv/ ). CGV visualizes pairwise same-species and cross-species alignments p…
Rapid and sensitive detection of genome contamination at scale with FCS-GX Open
Assembled genome sequences are being generated at an exponential rate. Here we present FCS-GX, part of NCBI’s Foreign Contamination Screen (FCS) tool suite, optimized to identify and remove contaminant sequences in new genomes. FCS-GX scre…
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly Open
The human reference genome assembly plays a central role in nearly all aspects of today's basic and clinical research. GRCh38 is the first coordinate-changing assembly update since 2009; it reflects the resolution of roughly 1000 issues an…
A New Chicken Genome Assembly Provides Insight into Avian Genome Structure Open
The importance of the Gallus gallus (chicken) as a model organism and agricultural animal merits a continuation of sequence assembly improvement efforts. We present a new version of the chicken genome assembly (Gallus_gallus-5.0; GCA_00000…
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly Open
The human reference genome assembly plays a central role in nearly all aspects of today’s basic and clinical research. GRCh38 is the first coordinate-changing assembly update since 2009 and reflects the resolution of roughly 1000 issues an…
View article: High-Quality Assembly of an Individual of Yoruban Descent
High-Quality Assembly of an Individual of Yoruban Descent Open
De novo assembly of human genomes is now a tractable effort due in part to advances in sequencing and mapping technologies. We use PacBio single-molecule, real-time (SMRT) sequencing and BioNano genomic maps to construct the first de novo …