Explanipedia

Celebrating 50 Years of Surface Enhanced Spectroscopy Open

Alexandre G. Brolo, Nathan C. Lindquist · 2024

Rapid on-site amplification and visual detection of misfolded proteins via microfluidic quaking-induced conversion (Micro-QuIC) Open

Dong Jun Lee, Peter R. Christenson, Gage R. Rowden, Nathan C. Lindquist, Peter A. Larsen , et al. · 2024

Protein misfolding diseases, such as prion diseases, Alzheimer’s, and Parkinson’s, share a common molecular mechanism involving the misfolding and aggregation of specific proteins. There is an urgent need for point-of-care (POC) diagnostic…

Developing optical devices and projects for teaching engineering Open

N. Lemke, Karen Rogers, Nathan C. Lindquist, Keith Stein, Grace Riermann , et al. · 2024

We are creating a suite of tools and techniques based on optics to be used for teaching a variety of engineering topics. Each tool is intended for non-expert use and without the need for high-end equipment such as vibration-free optical ta…

Microfluidic Quaking-Induced Conversion (Micro-QuIC) for Rapid On-Site Amplification and Detection of Misfolded Proteins Open

Dong Jun Lee, Peter R. Christenson, Gage R. Rowden, Nathan C. Lindquist, Peter A. Larsen , et al. · 2023

Protein misfolding diseases, such as prion diseases, Alzheimer’s, and Parkinson’s, share a common molecular mechanism involving the misfolding and aggregation of specific proteins. There is an urgent need for point-of-care (POC) diagnostic…

Replication of patterned thin-film structures for use in plasmonics and metamaterials Open

David J. Norris, Sang Eon Han, Aditya Bhan, Prashant Nagpal, Nathan C. Lindquist , et al. · 2023

The present invention provides templating methods for replicating patterned metal films from a template substrate such as for use in plasmonic devices and metamaterials. Advantageously, the template substrate is reusable and can provide pl…

Nano‐Optical Tweezers: Methods and Applications for Trapping Single Molecules and Nanoparticles Open

Joshua D. Kolbow, Nathan C. Lindquist, Christopher T. Ertsgaard, Daehan Yoo, Sang‐Hyun Oh · 2021

The front cover artwork is provided by Prof. Sang‐Hyun Oh's group at the University of Minnesota. The image shows the optical trapping of chiral nanoparticles using coaxial nano‐optical tweezers, devices capable of harnessing light to mani…

Digital plasmonic holography with iterative phase retrieval for sensing Open

Ryan M. Spies, Grace H. Cole, Marit A. Engevik, Britta G. Nordberg, Evan A. Scharnick , et al. · 2021

Propagating surface plasmon waves have been used for many applications including imaging and sensing. However, direct in-plane imaging of micro-objects with surface plasmon waves suffers from the lack of simple, two-dimensional lenses, mir…

The Collaborative Place-making Approach: Increasing Public Support for Density Open

Nathan C. Lindquist · 2019

As urban neighborhoods in many cities revitalize, planners pushing for increased density often come into conflict with local stakeholders who are wary of increased density in their neighborhoods. In order to obtain public support for incre…

Digital plasmonic holography Open

Joseph W. Nelson, Greta R. Knefelkamp, Alexandre G. Brolo, Nathan C. Lindquist · 2018

Chemically imaging bacteria with super-resolution SERS on ultra-thin silver substrates Open

Aeli P. Olson, Kelsey B. Spies, Anna C. Browning, Paula A. G. Soneral, Nathan C. Lindquist · 2017

Split-Wedge Antennas with Sub-5 nm Gaps for Plasmonic Nanofocusing Open

Xiaoshu Chen, Nathan C. Lindquist, Daniel J. Klemme, Prashant Nagpal, David J. Norris , et al. · 2016

We present a novel plasmonic antenna structure, a split-wedge antenna, created by splitting an ultrasharp metallic wedge with a nanogap perpendicular to its apex. The nanogap can tightly confine gap plasmons and boost the local optical fie…

Terahertz Waves: Perfect Extinction of Terahertz Waves in Monolayer Graphene over 2‐nm‐Wide Metallic Apertures (Advanced Optical Materials 5/2015) Open

Hyeong‐Ryeol Park, Seon Namgung, Xiaoshu Chen, Nathan C. Lindquist, Vincenzo Giannini , et al. · 2015

For enhanced light–matter interactions with 2D materials, ultra-small metallic nanogaps can be utilized. As shown in the image from S.-H. Oh and co-workers, light incident from below is strongly confined within these annular gaps and effic…

Polarization interferometry for real-time spectroscopic plasmonic sensing Open

Lauren M. Otto, Daniel A. Mohr, Timothy W. Johnson, Sang‐Hyun Oh, Nathan C. Lindquist · 2015

We present quantitative, spectroscopic polarization interferometry phase measurements on plasmonic surfaces for sensing applications. By adding a liquid crystal variable wave plate in our beam path, we are able to measure phase shifts due …

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