Nathan F. Johnson
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View article: Feasibility of Contrasting Brain Connectivity Patterns in Cognitive and Motor Cerebral Networks to Clinical Outcomes in Patients Surviving Acute Respiratory Failure: A Pilot Study
Feasibility of Contrasting Brain Connectivity Patterns in Cognitive and Motor Cerebral Networks to Clinical Outcomes in Patients Surviving Acute Respiratory Failure: A Pilot Study Open
fMRI is feasible to assess ARF patients' post-ICU limitations, as low post-ARF brain connectivity may be linked to low physical function, providing potential development of therapeutic interventions.
View article: Sensorimotor Connectivity is related to Static Postural Control in Older Adults with History of Lateral Ankle Sprain
Sensorimotor Connectivity is related to Static Postural Control in Older Adults with History of Lateral Ankle Sprain Open
Context: The Sensorimotor Network (SMN) is often overlooked when determining relationships between postural control and sensorimotor function. SMN functional connectivity (FC) represents the temporal synchrony of functionally linked but sp…
View article: A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome
A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome Open
Background People with Down syndrome (DS) develop Alzheimer's disease (AD) at an earlier age of onset than those with sporadic AD. AD neuropathology is typically present in DS by 40 years of age with an onset of dementia approximately 10 y…
View article: Cardiorespiratory fitness diminishes the effects of age on white matter hyperintensity volume
Cardiorespiratory fitness diminishes the effects of age on white matter hyperintensity volume Open
White matter hyperintensities (WMHs) are among the most commonly observed marker of cerebrovascular disease. Age is a key risk factor for WMH development. Cardiorespiratory fitness (CRF) is associated with increased vessel compliance, but …
View article: Health-Related Quality of Life Among Middle-Aged Adults With Chronic Ankle Instability, Copers, and Uninjured Controls
Health-Related Quality of Life Among Middle-Aged Adults With Chronic Ankle Instability, Copers, and Uninjured Controls Open
Context People with chronic ankle instability (CAI) display a lower regional and global health-related quality of life (HRQoL). Examinations of HRQoL outcomes associated with CAI have addressed younger adults, restricting our understanding…
View article: Non-fasting High-Density Lipoprotein Is Associated With White Matter Microstructure in Healthy Older Adults
Non-fasting High-Density Lipoprotein Is Associated With White Matter Microstructure in Healthy Older Adults Open
A growing body of evidence indicates that biomarkers of cardiovascular risk may be related to cerebral health. However, little is known about the role that non-fasting lipoproteins play in assessing age-related declines in a cerebral bioma…
View article: Moving beyond the 10-minute bout in the 2018 US Physical Activity Guidelines: could high intensity incidental physical activity be the new HIIT
Moving beyond the 10-minute bout in the 2018 US Physical Activity Guidelines: could high intensity incidental physical activity be the new HIIT Open
Moving beyond the 10-minute bout in the 2018 US Physical Activity Guidelines: could high intensity incidental physical activity be the new HIIT?
View article: Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β<sub>1-42</sub> and Hypertension
Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β<sub>1-42</sub> and Hypertension Open
Background: Alzheimer’s disease (AD) pathology and hypertension (HTN) are risk factors for development of white matter (WM) alterations and might be independently associated with these alterations in older adults. Objective: To evaluate th…
View article: Dynamic range of frontoparietal functional modulation is associated with working memory capacity limitations in older adults
Dynamic range of frontoparietal functional modulation is associated with working memory capacity limitations in older adults Open
View article: Endothelial Function Is Associated with White Matter Microstructure and Executive Function in Older Adults
Endothelial Function Is Associated with White Matter Microstructure and Executive Function in Older Adults Open
Age-related declines in endothelial function can lead to cognitive decline. However, little is known about the relationships between endothelial function and specific neurocognitive functions. This study explored the relationship between m…
View article: Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes
Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes Open
View article: Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease
Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease Open
We developed a merged younger-older adult template of the fornix and demonstrated its utility for studies of aging and preclinical Alzheimer's disease (AD). In Experiment 1, probabilistic tractography was used to reconstruct the fornix in …
View article: BMET-07. PROGNOSTIC DIFFERENTIAL GENE EXPRESSION PROFILING FOR DEVELOPMENT OF BRAIN METASTASIS IN CUTANEOUS MELANOMA VARIES BASED ON SITE OF TISSUE SAMPLED
BMET-07. PROGNOSTIC DIFFERENTIAL GENE EXPRESSION PROFILING FOR DEVELOPMENT OF BRAIN METASTASIS IN CUTANEOUS MELANOMA VARIES BASED ON SITE OF TISSUE SAMPLED Open
Our ability to predict brain metastasis in melanoma is poor. Gene expression profiling (GEP) of tumor samples could provide prognostic information by identifying genes that are differentially expressed between melanoma patients who do and …
View article: Participant Information Sheet - Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes
Participant Information Sheet - Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes Open
View article: Participation Consent Form - Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes
Participation Consent Form - Targeting metabolic and vascular health with high intensity exercise training in type 2 diabetes Open
View article: White matter microstructure contributes to age-related declines in task-induced deactivation of the default mode network
White matter microstructure contributes to age-related declines in task-induced deactivation of the default mode network Open
Task-induced deactivations within the brain's default mode network (DMN) are thought to reflect suppression of endogenous thought processes to support exogenous goal-directed task processes. Older adults are known to show reductions in dea…
View article: Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults
Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults Open
View article: Longitudinal alterations to brain function, structure, and cognitive performance in healthy older adults: A fMRI-DTI study
Longitudinal alterations to brain function, structure, and cognitive performance in healthy older adults: A fMRI-DTI study Open