Nathan Ing
YOU?
Author Swipe
View article: Spatial transcriptomic analysis of immune checkpoint blockade response in triple negative breast cancers with tertiary lymphoid structures
Spatial transcriptomic analysis of immune checkpoint blockade response in triple negative breast cancers with tertiary lymphoid structures Open
Tertiary lymphoid structures (TLSs) are associated with improved cancer immunotherapy responses. However, TLSs vary in their ability to elicit anticancer immune activity, so it is important to develop databases that allow study of variable…
View article: Single RNA molecule resolution spatial imaging of immunotherapy response in triple negative breast tumors harboring tertiary lymphoid structures
Single RNA molecule resolution spatial imaging of immunotherapy response in triple negative breast tumors harboring tertiary lymphoid structures Open
Summary Cancer immunotherapy trials have had variable success, prompting a search for biomarkers of response. Tertiary lymphoid structures (TLS) have emerged as prognostic for multiple tumor types. These ectopic immunological bodies resemb…
View article: Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast
Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast Open
This repository contains raw and processed data from the CODEX imaging dataset in this publication. The RAW data tables provide the resulting nuclei and membrane staining signals obtained from the nuclei segmentation described in the Metho…
View article: Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast
Tissue microarray data and processing scripts for The molecular consequences of androgen activity in the human breast Open
This repository contains raw and processed data from the CODEX imaging dataset in this publication. The RAW data tables provide the resulting nuclei and membrane staining signals obtained from the nuclei segmentation described in the Metho…
View article: The molecular consequences of androgen activity in the human breast
The molecular consequences of androgen activity in the human breast Open
Estrogen and progesterone have been extensively studied in the mammary gland, but the molecular effects of androgen remain largely unexplored. Transgender men are recorded as female at birth but identify as male and may undergo gender-affi…
View article: The molecular consequences of androgen activity in the human breast
The molecular consequences of androgen activity in the human breast Open
Summary The mammary gland has been extensively studied for estrogen and progesterone reactivity, but the molecular effects of androgen in the breast remain largely unexplored. Transgender men are recorded female at birth but identify as ma…
View article: An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer
An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer Open
Neoadjuvant chemotherapy (NAC) prior to surgery and immune checkpoint therapy (ICT) have revolutionized bladder cancer management. However, stratification of patients that would benefit most from these modalities remains a major clinical c…
View article: KnottLab/codex: Matlab v10
KnottLab/codex: Matlab v10 Open
This is the matlab code for the CODEX image processing pipeline.
View article: KnottLab/bladder-snSeq: Analysis scripts
KnottLab/bladder-snSeq: Analysis scripts Open
Analysis scripts for bladder tumor single nucleus sequencing data
View article: Determination of the relationship between vancomycin trough concentrations and the AUC/MIC Dosing
Determination of the relationship between vancomycin trough concentrations and the AUC/MIC Dosing Open
Rationale: The recently revised guidelines for the therapeutic monitoring of
\nvancomycin recommend targeting an AUC/MIC of 400-600 for serious
\nmethicillin-resistant Staphylococcus aureus (MRSA) infections. The
\nfeasibility of transitio…
View article: PD11-02 DEVELOPMENT AND APPLICATION OF A DIGITAL IMAGE ANALYSIS CLASSIFIER FOR DIAGNOSTIC PROSTATE NEEDLE BIOPSIES TO PREDICT METASTASES
PD11-02 DEVELOPMENT AND APPLICATION OF A DIGITAL IMAGE ANALYSIS CLASSIFIER FOR DIAGNOSTIC PROSTATE NEEDLE BIOPSIES TO PREDICT METASTASES Open
You have accessJournal of UrologyProstate Cancer: Markers I (PD11)1 Apr 2019PD11-02 DEVELOPMENT AND APPLICATION OF A DIGITAL IMAGE ANALYSIS CLASSIFIER FOR DIAGNOSTIC PROSTATE NEEDLE BIOPSIES TO PREDICT METASTASES Nathan Ing, Fangjin Huang,…
View article: Convolutional neural networks can accurately distinguish four histologic growth patterns of lung adenocarcinoma in digital slides
Convolutional neural networks can accurately distinguish four histologic growth patterns of lung adenocarcinoma in digital slides Open
During the diagnostic workup of lung adenocarcinomas (LAC), pathologists evaluate distinct histological tumor growth patterns. The percentage of each pattern on multiple slides bears prognostic significance. To assist with the quantificati…
View article: A novel machine learning approach reveals latent vascular phenotypes predictive of renal cancer outcome
A novel machine learning approach reveals latent vascular phenotypes predictive of renal cancer outcome Open
Gene expression signatures are commonly used as predictive biomarkers, but do not capture structural features within the tissue architecture. Here we apply a 2-step machine learning framework for quantitative imaging of tumor vasculature t…
View article: MP21-02 NOVEL QUANTITATIVE IMAGING ALGORITHMS DISTINGUISH LOCALIZED AND METASTATIC HIGH-GRADE PRIMARY PROSTATE CANCERS
MP21-02 NOVEL QUANTITATIVE IMAGING ALGORITHMS DISTINGUISH LOCALIZED AND METASTATIC HIGH-GRADE PRIMARY PROSTATE CANCERS Open
You have accessJournal of UrologyProstate Cancer: Detection & Screening III1 Apr 2016MP21-02 NOVEL QUANTITATIVE IMAGING ALGORITHMS DISTINGUISH LOCALIZED AND METASTATIC HIGH-GRADE PRIMARY PROSTATE CANCERS Eric Miller, Arkadiusz Gertych, Zha…