Nathan R. Steffens
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View article: Prenatal Oxygen and Glucose Therapy Normalizes Insulin Secretion and Action in Growth-Restricted Fetal Sheep
Prenatal Oxygen and Glucose Therapy Normalizes Insulin Secretion and Action in Growth-Restricted Fetal Sheep Open
Placental insufficiency (PI) lowers fetal oxygen and glucose concentrations, which disrupts glucose-insulin homeostasis and promotes fetal growth restriction (FGR). To date, prenatal treatments for FGR have not attempted to correct the oxy…
View article: Augmented glucose production is not contingent on high catecholamines in fetal sheep with IUGR
Augmented glucose production is not contingent on high catecholamines in fetal sheep with IUGR Open
Fetuses with intrauterine growth restriction (IUGR) have high concentrations of catecholamines, which lowers the insulin secretion and glucose uptake. Here, we studied the effect of hypercatecholaminemia on glucose metabolism in sheep fetu…
View article: Chronically elevated norepinephrine concentrations lower glucose uptake in fetal sheep
Chronically elevated norepinephrine concentrations lower glucose uptake in fetal sheep Open
Fetal conditions associated with placental insufficiency and intrauterine growth restriction (IUGR) chronically elevate plasma norepinephrine (NE) concentrations. Our objective was to evaluate the effects of chronically elevated NE on insu…