Nathan Witman
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Unique extrafollicular B cell expansion in COVID-19 patients who developed prothrombotic platelet-activating antibodies 2427 Open
Description Despite vaccine development, COVID-19 morbidity and mortality remain high, with thrombotic complications contributing significantly to severe cases. Our lab has identified a subset of hospitalized COVID-19 patients who develop …
View article: A Subset of Antibodies to the Spike Protein's Receptor-Binding Domain in Severe COVID-19 Activate Platelets
A Subset of Antibodies to the Spike Protein's Receptor-Binding Domain in Severe COVID-19 Activate Platelets Open
Severe COVID-19 is a multisystem condition with thromboinflammation as a significant driver of morbidity and mortality. Cellular components involved in inflammatory and coagulation responses include platelets, endothelium, monocytes, and n…
Treatment with gut-specific nonsteroidal anti-inflammatory drug attenuates metabolic inflammation but not body mass in fattening ground squirrels Open
Adiposity and obesity are caused, at least in part, by inflammation of metabolic tissues. Hibernators, like ground squirrels, undergo this same metabolic inflammation during their summer fattening period. We attempted to curb this inflamma…
Treatment with Gut-Specific Nonsteroidal Anti-Inflammatory Drug Attenuates Metabolic Inflammation but not Body Mass in Fattening Ground Squirrels Open
16S rRNA V4 region sequences from the 13-lined ground squirrel gut microbiome, that received mesalazine or control treatment during the active season.