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Nathaniel J. Clark Uncle Sam recruitment poster (US) YOU? Author Swipe

View article: Determining the accumulation potential of nanoplastics in crops: An investigation of 14C-labelled polystyrene nanoplastic into radishes
Determining the accumulation potential of nanoplastics in crops: An investigation of 14C-labelled polystyrene nanoplastic into radishes Open
Nathaniel J. Clark, Astrid Fischer, Demelza Carne, George R. Littlejohn, Lee J. Durndell , et al. · 2025
The capacity of crops to accumulate nanoplastics has remained relatively unexplored largely due to analytical constraints. To address this challenge, the present study employed a radiolabelling approach to demonstrate, for the first time, …
View article: Micro(nano)plastics in the fish gastrointestinal tract: A mini review and relevance to One Health perspective
Micro(nano)plastics in the fish gastrointestinal tract: A mini review and relevance to One Health perspective Open
Farhan R. Khan, Nathaniel J. Clark, Elvis Genbo Xu · 2025
View article: Nitrate, Nitrite, and Iodine Concentrations in Commercial Edible Algae: An Observational Study
Nitrate, Nitrite, and Iodine Concentrations in Commercial Edible Algae: An Observational Study Open
Patricia Casas‐Agustench, Jade M. Hayter, Odelia S. B. Ng, Lauren V. Hallewell, Nathaniel J. Clark , et al. · 2024
Edible algae are a natural source of nutrients, including iodine, and can also contain nitrogen in the form of nitrate (NO3−) and nitrite (NO2−) as they can fix nitrogen from seawater. This study aimed to analyse the NO3−, NO2−, and iodine…
View article: Physicochemical and metagenomic analysis of samples from the Roman Baths (Bath, UK) reveals high bacterial and archaeal diversity and a potential for antimicrobial discovery
Physicochemical and metagenomic analysis of samples from the Roman Baths (Bath, UK) reveals high bacterial and archaeal diversity and a potential for antimicrobial discovery Open
Enus Fina, Michele Kiernan, Bonnie Whatmough, Nathaniel J. Clark, Jazmin Conway , et al. · 2024
Antimicrobial resistance of pathogenic bacteria to currently used antibiotics killed an estimated 1.27 million people in 2019 and it is believed that this toll will increase to 10 million per year by 2050. This remains one of the most urge…
View article: Zinc oxide nanoparticles disrupt development and function of the olfactory sensory system impairing olfaction-mediated behaviour in zebrafish
Zinc oxide nanoparticles disrupt development and function of the olfactory sensory system impairing olfaction-mediated behaviour in zebrafish Open
Aya Takesono, Sylvia Dimitriadou, Nathaniel J. Clark, Richard D. Handy, Sulayman Mourabit , et al. · 2023
Zinc (Zn) is an essential metal present in numerous enzymes throughout the body, playing a vital role in animal and human health. However, the increasing use of zinc oxide nanomaterials (ZnONPs) in a diverse range of products has raised co…
View article: Translocation of 14C-polystyrene nanoplastics into fish during a very-low concentration dietary exposure
Translocation of 14C-polystyrene nanoplastics into fish during a very-low concentration dietary exposure Open
Nathaniel J. Clark, Astrid Fischer, Lee J. Durndell, Tamara S. Galloway, Richard C. Thompson · 2023
Assessing the dietary accumulation of nanoplastics in animals following very-low exposure concentrations is restricted due to analytical limitations. This study adapted a method for synthesising semi-stable 14C-PS NPs (through s…
View article: Toward Understanding the Environmental Risks of Combined Microplastics/Nanomaterials Exposures: Unveiling ZnO Transformations after Adsorption onto Polystyrene Microplastics in Environmental Solutions
Toward Understanding the Environmental Risks of Combined Microplastics/Nanomaterials Exposures: Unveiling ZnO Transformations after Adsorption onto Polystyrene Microplastics in Environmental Solutions Open
Miguel A. Gomez‐Gonzalez, Tatiana Da Silva‐Ferreira, Nathaniel J. Clark, Robert Clough, Paul D. Quinn , et al. · 2023
Over recent decades, there has been a dramatic increase in the manufacture of engineered nanomaterials, which has inevitably led to their environmental release. Zinc oxide (ZnO) is among the more abundant nanomaterial manufactured due to i…
View article: Toxicokinetics and bioaccumulation of silver sulfide nanoparticles in benthic invertebrates in an indoor stream mesocosm
Toxicokinetics and bioaccumulation of silver sulfide nanoparticles in benthic invertebrates in an indoor stream mesocosm Open
Patrícia V. Silva, Ana Rita R. Silva, Nathaniel J. Clark, Joanne Vassallo, Marta Baccaro , et al. · 2023
View article: Physicochemical and Metagenomic Analysis of Samples from the Roman Baths (Bath, UK) Reveals High Bacterial and Archaeal Diversity and a Potential for Antimicrobial Discovery
Physicochemical and Metagenomic Analysis of Samples from the Roman Baths (Bath, UK) Reveals High Bacterial and Archaeal Diversity and a Potential for Antimicrobial Discovery Open
Enus Fina, Michele Kiernan, Bonnie Whatmough, Nathaniel J. Clark, Jazmin Conway , et al. · 2023
View article: Uptake, distribution and elimination of palladium-doped polystyrene nanoplastics in rainbow trout (Oncorhynchus mykiss) following dietary exposure
Uptake, distribution and elimination of palladium-doped polystyrene nanoplastics in rainbow trout (Oncorhynchus mykiss) following dietary exposure Open
Nathaniel J. Clark, Farhan R. Khan, Charlotte Crowther, Denise M. Mitrano, Richard C. Thompson · 2022
View article: The ecotoxicological consequences of microplastics and co-contaminants in aquatic organisms: a mini-review
The ecotoxicological consequences of microplastics and co-contaminants in aquatic organisms: a mini-review Open
Farhan R. Khan, Ana I. Catarino, Nathaniel J. Clark · 2022
Microplastics (MPs, <5 mm in size) are a grave environmental concern. They are a ubiquitous persistent pollutant group that has reached into all parts of the environment — from the highest mountain tops to the depths of the ocean. Durin…
View article: Metal transfer to sediments, invertebrates and fish following waterborne exposure to silver nitrate or silver sulfide nanoparticles in an indoor stream mesocosm
Metal transfer to sediments, invertebrates and fish following waterborne exposure to silver nitrate or silver sulfide nanoparticles in an indoor stream mesocosm Open
Nathaniel J. Clark, Joanne Vassallo, Patrícia V. Silva, Ana Rita R. Silva, Marta Baccaro , et al. · 2022
View article: Determination of metallic nanoparticles in biological samples by single particle ICP-MS: a systematic review from sample collection to analysis
Determination of metallic nanoparticles in biological samples by single particle ICP-MS: a systematic review from sample collection to analysis Open
Adam Laycock, Nathaniel J. Clark, Robert Clough, Rachel Smith, Richard D. Handy · 2022
A systematic review of the use of single particle ICP-MS to analyse engineered nanomaterials in biological samples has highlighted that efforts have focused on a select few compositions and there is a lack of information for some important…
View article: Toxicokinetics and Bioaccumulation Of Silver Sulfide Nanoparticles in Benthic Invertebrates in an Indoor Stream Mesocosm
Toxicokinetics and Bioaccumulation Of Silver Sulfide Nanoparticles in Benthic Invertebrates in an Indoor Stream Mesocosm Open
Patrícia V. Silva, Ana Rita R. Silva, Nathaniel J. Clark, Joanne Vassallo, Marta Baccaro , et al. · 2022
View article: The bioaccumulation testing strategy for nanomaterials: correlations with particle properties and a meta-analysis of<i>in vitro</i>fish alternatives to<i>in vivo</i>fish tests
The bioaccumulation testing strategy for nanomaterials: correlations with particle properties and a meta-analysis of<i>in vitro</i>fish alternatives to<i>in vivo</i>fish tests Open
Richard D. Handy, Nathaniel J. Clark, David Boyle, Joanne Vassallo, Christopher Green , et al. · 2022
This meta-analysis identifies linkages between the tiers in the bioaccumulation testing strategy.
View article: Demonstrating the translocation of nanoplastics across the fish intestine using palladium-doped polystyrene in a salmon gut-sac
Demonstrating the translocation of nanoplastics across the fish intestine using palladium-doped polystyrene in a salmon gut-sac Open
Nathaniel J. Clark, Farhan R. Khan, Denise M. Mitrano, David Boyle, Richard C. Thompson · 2021
View article: The bioaccumulation testing strategy for manufactured nanomaterials: physico-chemical triggers and read across from earthworms in a meta-analysis
The bioaccumulation testing strategy for manufactured nanomaterials: physico-chemical triggers and read across from earthworms in a meta-analysis Open
Richard D. Handy, Nathaniel J. Clark, Joanne Vassallo, Christopher Green, Fatima Nasser , et al. · 2021
How to use chemical triggers and invertebrate tests in the lower tiers of a bioaccumulation testing strategy.
View article: Dietary exposure to copper sulphate compared to a copper oxide nanomaterial in rainbow trout: bioaccumulation with minimal physiological effects
Dietary exposure to copper sulphate compared to a copper oxide nanomaterial in rainbow trout: bioaccumulation with minimal physiological effects Open
David Boyle, Nathaniel J. Clark, Benjamin Eynon, Richard D. Handy · 2021
The dietary bioaccumulation potential of engineered nanomaterials (ENMs) remains poorly understood.
View article: Quantification of particulate Ag in rainbow trout organs following dietary exposure to silver nitrate, or two forms of engineered silver nanoparticles
Quantification of particulate Ag in rainbow trout organs following dietary exposure to silver nitrate, or two forms of engineered silver nanoparticles Open
Nathaniel J. Clark, Robert Clough, David Boyle, Richard D. Handy · 2021
Following exposure to a diet containing a control (no added Ag), AgNO3, Ag NPs or Ag2S NPs, Ag-containing particles were found in organs of all treatments, with the highest concentrations following exposure to AgNO
View article: Dietary bioaccumulation potential of silver nanomaterials compared to silver nitrate in wistar rats using an ex vivo gut sac technique
Dietary bioaccumulation potential of silver nanomaterials compared to silver nitrate in wistar rats using an ex vivo gut sac technique Open
Nathaniel J. Clark, Waldemar Woznica, Richard D. Handy · 2020
View article: Polyvinyl chloride (PVC) plastic fragments release Pb additives that are bioavailable in zebrafish
Polyvinyl chloride (PVC) plastic fragments release Pb additives that are bioavailable in zebrafish Open
David Boyle, Ana I. Catarino, Nathaniel J. Clark, Theodore B. Henry · 2020
View article: Comparison of the dietary bioavailability of copper sulphate and copper oxide nanomaterials in<i>ex vivo</i>gut sacs of rainbow trout: effects of low pH and amino acids in the lumen
Comparison of the dietary bioavailability of copper sulphate and copper oxide nanomaterials in<i>ex vivo</i>gut sacs of rainbow trout: effects of low pH and amino acids in the lumen Open
David Boyle, Nathaniel J. Clark, Tarryn L. Botha, Richard D. Handy · 2020
Diet is an important exposure pathway of engineered nanomaterials (ENMs) in fish, but the long duration ofin vivotoxicity tests is a barrier to hazard assessment.
View article: The gut barrier and the fate of engineered nanomaterials: a view from comparative physiology
The gut barrier and the fate of engineered nanomaterials: a view from comparative physiology Open
Meike van der Zande, Anita Jemec Kokalj, David J. Spurgeon, Susana Loureiro, Patrícia V. Silva , et al. · 2020
Despite the diverse structures and functions of the gut barrier in the animal kingdom, some common features of gut lumen chemistry control the behaviour of engineered nanomaterials, and with some potentially novel uptake pathways in invert…
View article: Toxicities of copper oxide nanomaterial and copper sulphate in early life stage zebrafish: Effects of pH and intermittent pulse exposure
Toxicities of copper oxide nanomaterial and copper sulphate in early life stage zebrafish: Effects of pH and intermittent pulse exposure Open
David Boyle, Nathaniel J. Clark, Richard D. Handy · 2019
View article: An assessment of the dietary bioavailability of silver nanomaterials in rainbow trout using an<i>ex vivo</i>gut sac technique
An assessment of the dietary bioavailability of silver nanomaterials in rainbow trout using an<i>ex vivo</i>gut sac technique Open
Nathaniel J. Clark, David Boyle, Richard D. Handy · 2019
The uptake of engineered nanomaterials (ENMs) by the gut of fishes is poorly understood.
View article: Dietary exposure to silver nitrate compared to two forms of silver nanoparticles in rainbow trout: bioaccumulation potential with minimal physiological effects
Dietary exposure to silver nitrate compared to two forms of silver nanoparticles in rainbow trout: bioaccumulation potential with minimal physiological effects Open
Nathaniel J. Clark, David Boyle, Benjamin Eynon, Richard D. Handy · 2019
Overall, fish showed more Ag accumulation from AgNO3 and Ag NP exposures compared to the Ag2S NP treatment.
View article: Development of a suitable detection method for silver nanoparticles in fish tissue using single particle ICP-MS
Development of a suitable detection method for silver nanoparticles in fish tissue using single particle ICP-MS Open
Nathaniel J. Clark, Robert Clough, David Boyle, Richard D. Handy · 2019
A strong alkali extraction technique and suitable single particle ICP-MS method is described for the routine quantifying of particle number concentration, particle size and particle mass concentration for silver nanomaterials in fish tissu…
View article: The Dietary Bioaccumulation and Detection of Engineered Nanosilver in Fish
The Dietary Bioaccumulation and Detection of Engineered Nanosilver in Fish Open
Nathaniel J. Clark · 2019
Emerging contaminants, including engineered nanomaterials (ENMs), need to undergo environmental risk assessment, whereby they are tested for properties of persistence in the environment, toxicity or bioaccumulation. To date, little data ex…
View article: Low hazard of silver nanoparticles and silver nitrate to the haematopoietic system of rainbow trout
Low hazard of silver nanoparticles and silver nitrate to the haematopoietic system of rainbow trout Open
Nathaniel J. Clark, Benjamin J. Shaw, Richard D. Handy · 2018




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