Nathaniel M Schuster
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View article: Vaporized cannabis versus placebo for acute migraine: A randomized, double‐blind, placebo‐controlled crossover trial
Vaporized cannabis versus placebo for acute migraine: A randomized, double‐blind, placebo‐controlled crossover trial Open
Objective To assess the efficacy of cannabis for the treatment of acute migraine. Background Preclinical and retrospective studies suggest cannabinoids may be effective in migraine treatment. However, there have been no randomized clinical…
View article: A multi-ancestry meta genome-wide association study of migraine among veterans: associations with traumatic brain injury, depression, and post-traumatic stress disorder
A multi-ancestry meta genome-wide association study of migraine among veterans: associations with traumatic brain injury, depression, and post-traumatic stress disorder Open
Migraine is a neurovascular disorder that poses a high burden to Veterans, who face a greater risk than sex-matched individuals in the general population. Genetic research on migraine in Veterans and its link to psychiatric comorbidities i…
View article: Consensus practice guidelines on sacroiliac joint complex pain from a multispecialty, international working group
Consensus practice guidelines on sacroiliac joint complex pain from a multispecialty, international working group Open
Background The past two decades have witnessed tremendous growth in the appreciation and treatment of sacroiliac joint (SIJ) complex pain, including anatomical dissections that shed light on innervation, an appreciation for the contributio…
View article: A systematic review of evidence comparing spinal cord stimulation to sham or conservative medical management in the treatment of persistent spinal pain syndrome - Type 2
A systematic review of evidence comparing spinal cord stimulation to sham or conservative medical management in the treatment of persistent spinal pain syndrome - Type 2 Open
Substantial proportions of patients achieved ≥50% relief at 6 months following tonic SCS when compared with CMM, demonstrating clinical effectiveness. Significant improvements in function and quality of life were observed at study endpoint…
View article: Medical cannabis authorization and opioid milligram equivalents over time in patients with chronic pain: a retrospective analysis
Medical cannabis authorization and opioid milligram equivalents over time in patients with chronic pain: a retrospective analysis Open
Objective Strategies are needed for patients with chronic pain who are using opioids to safely and effectively wean opioids without worsening of pain. The objective was to measure associations between medical cannabis authorization (MCA) a…
View article: Quantitative assessment of conflicts of interest in reviews of spinal cord stimulation research
Quantitative assessment of conflicts of interest in reviews of spinal cord stimulation research Open
Journal Article Accepted manuscript Quantitative Assessment of Conflicts of Interest in Reviews of Spinal Cord Stimulation Research Get access Mustafa Broachwala, DO, Mustafa Broachwala, DO Department of Physical Medicine and Rehabilitatio…
View article: Migraine Prevalence, Environmental Risk, and Comorbidities in Men and Women Veterans
Migraine Prevalence, Environmental Risk, and Comorbidities in Men and Women Veterans Open
Importance Migraine is a prevalent and debilitating condition that substantially impacts quality of life. Investigating migraine prevalence, associated comorbidities, and potential military service exposures in veterans, focusing on gender…
View article: Vaporized Cannabis versus Placebo for Acute Migraine: A Randomized Controlled Trial
Vaporized Cannabis versus Placebo for Acute Migraine: A Randomized Controlled Trial Open
Background Preclinical and retrospective studies suggest cannabinoids may be effective in migraine treatment. However, there have been no randomized clinical trials examining the efficacy of cannabinoids for acute migraine. Methods In this…
View article: Use of spinal cord stimulation in treatment of intractable headache diseases
Use of spinal cord stimulation in treatment of intractable headache diseases Open
Headache diseases remain one of the leading causes of disability in the world. With the development of neuromodulation strategies, high cervical spinal cord stimulation (hcSCS) targeting the trigeminocervical complex has been deployed to t…
View article: The Use of Psychedelics in the Treatment of Medical Conditions: An Analysis of Currently Registered Psychedelics Studies in the American Drug Trial Registry
The Use of Psychedelics in the Treatment of Medical Conditions: An Analysis of Currently Registered Psychedelics Studies in the American Drug Trial Registry Open
Although early therapeutic research on psychedelics dates back to the 1940s, this field of investigation was met with many cultural and legal challenges in the 1970s. Over the past two decades, clinical trials using psychedelics have resum…
View article: Best practices for interventional pain procedures in the setting of an iodinated contrast media shortage: A multisociety practice advisory
Best practices for interventional pain procedures in the setting of an iodinated contrast media shortage: A multisociety practice advisory Open
Representatives from the Spine Intervention Society (SIS) and American Academy of Pain Medicine (AAPM) have developed the following best practice recommendations for the performance of interventional pain procedures in the setting of an io…
View article: Effects of Anti-CGRP monoclonal antibodies for episodic and chronic migraine on migraine characteristics, disability, impact and quality of life beyond 3 months of treatment: A Systematic review and Meta-analysis
Effects of Anti-CGRP monoclonal antibodies for episodic and chronic migraine on migraine characteristics, disability, impact and quality of life beyond 3 months of treatment: A Systematic review and Meta-analysis Open
Objective: At the time of this study, there were no systematic reviews to evaluate phase III RCT`s of CGRP monoclonal antibodies on migraine characteristics, migraine related disability, impact and quality of life after 3 months. This meta…
View article: The American Society of Pain and Neuroscience (ASPN) Practical Guidelines to Study Design and Scientific Manuscript Preparation in Neuromodulation
The American Society of Pain and Neuroscience (ASPN) Practical Guidelines to Study Design and Scientific Manuscript Preparation in Neuromodulation Open
This article should enable the reader to understand how to appropriately design a clinical research study and prepare scientific manuscripts. The high-quality and well-designed studies, when performed and reported effectively, support evid…
View article: International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020)
International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020) Open
Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation (tVNS) across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the au…
View article: Quality improvement in neurology
Quality improvement in neurology Open
Headache is the most frequent reason for a person to seek care from a neurologist and is the most common subspecialty practice focus identified by neurologists.1 Although headache is most commonly encountered in primary care,2,3 it is also…
View article: Crossing Midline and Oblique Imaging During Interlaminar Cervical Epidural Steroid Injection
Crossing Midline and Oblique Imaging During Interlaminar Cervical Epidural Steroid Injection Open
afterwards.For example, hyperglycemia in diabetic patients may elevate blood sugars after an ESI for up to two weeks.In the case of adrenal insufficiency, cortisol levels may be decreased for weeks after an injection.These two topics are d…
View article: Emerging Subspecialties in Neurology: Pain medicine
Emerging Subspecialties in Neurology: Pain medicine Open
Pain medicine is a multidisciplinary field specializing in the diagnosis and treatment of chronic pain anywhere in the body. Neurologists have a long history of contributions to the field of pain medicine, and in our experience, today's ge…
View article: Lasmiditan for the treatment of acute migraine: a review and potential role in clinical practice
Lasmiditan for the treatment of acute migraine: a review and potential role in clinical practice Open
Now that the vascular hypothesis of migraine is no longer the prevailing theory of migraine pathogenesis, there is interest in developing acute migraine treatments that act exclusively on non-vascular targets. There is a large percentage o…