Nathaniel S. Treister
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View article: US expert Delphi consensus on the prevention and management of stomatitis in patients treated with datopotamab deruxtecan
US expert Delphi consensus on the prevention and management of stomatitis in patients treated with datopotamab deruxtecan Open
Summary Background Datopotamab deruxtecan (Dato-DXd) is an investigational antibody–drug conjugate that has shown promising results in phase III clinical trials of lung and breast cancers. Stomatitis is a common adverse event associated wi…
View article: The impact of medications on salivary flow and oral health-related quality of life in postradiation head and neck cancer patients: results of the OraRad study
The impact of medications on salivary flow and oral health-related quality of life in postradiation head and neck cancer patients: results of the OraRad study Open
Antidepressants were associated with reduced stimulated salivary flow, but no cumulative negative effect on whole stimulated salivary flow was identified. Polypharmacy was associated with worse OH-QOL.
View article: How Oral Medicine Practice Is Reported: A Scoping Review of 114,971 Patients
How Oral Medicine Practice Is Reported: A Scoping Review of 114,971 Patients Open
Objective This review aimed to: (i) identify the variables used by oral medicine services (OMS) to describe the scope of their clinical practices and (ii) identify gaps in the availability of these variables in the literature to guide futu…
View article: Iatrogenic Head and Neck Necrosis of Bone and Soft Tissue in Cancer Patients
Iatrogenic Head and Neck Necrosis of Bone and Soft Tissue in Cancer Patients Open
Background Cancer patients are at risk of developing a wide range of treatment‐related toxicities that may affect the head and neck region. Iatrogenic necrosis of bone and soft tissue in this area represents a distinct clinical entity char…
View article: Belumosudil reduces oral chronic graft-versus-host disease tissue inflammation and fibrosis: a ROCKstar companion study
Belumosudil reduces oral chronic graft-versus-host disease tissue inflammation and fibrosis: a ROCKstar companion study Open
Belumosudil (KD025), an oral, selective, Rho-associated, coiled-coil–containing protein kinase 2 (ROCK2) inhibitor, is approved for third-line treatment of chronic graft-versus-host disease (cGVHD). Previous studies demonstrated that ROCK2…
View article: Oral Chronic Graft-Versus-Host Disease: Pathogenesis, Diagnosis, Current Treatment, and Emerging Therapies
Oral Chronic Graft-Versus-Host Disease: Pathogenesis, Diagnosis, Current Treatment, and Emerging Therapies Open
Chronic graft-versus-host disease (cGvHD) is a multisystem disorder that occurs in recipients of allogeneic hematopoietic (alloHCT) stem cell transplants and is characterized by both inflammatory and fibrotic manifestations. It begins with…
View article: Salivary metabolomics in oral cancer: A systematic review
Salivary metabolomics in oral cancer: A systematic review Open
Diagnosis of oral squamous cell carcinoma (OSCC) is frequently delayed, with most tumors being detected in advanced stages.Saliva may represent the ideal fluid for early detection of dysplastic and malignant oral lesions. Among available s…
View article: Oral Chronic Graft-versus-Host Disease and Oral Health after Allogeneic Hematopoietic Cell Transplantation — What the Care Team Needs to Know
Oral Chronic Graft-versus-Host Disease and Oral Health after Allogeneic Hematopoietic Cell Transplantation — What the Care Team Needs to Know Open
Oral chronic graft-versus-host disease (cGVHD) can present with a multitude of clinical signs and is associated with morbidity and lower quality of life. Oral cGVHC may affect the oral mucosa (reticular white striae, erythema, and/or ulcer…
View article: Females have lower salivary flow than males, before and after radiation therapy for head/neck cancer
Females have lower salivary flow than males, before and after radiation therapy for head/neck cancer Open
Objective To compare salivary flow rates between females and males, before and after radiation therapy (RT) for head and neck cancer (HNC). Methods Prospective observational multicenter cohort study (OraRad). Stimulated whole salivary flow…
View article: Microbiota signature of oral chronic graft-<i>versus</i>-host disease 6+ years after transplantation
Microbiota signature of oral chronic graft-<i>versus</i>-host disease 6+ years after transplantation Open
Not available.
View article: Nivolumab for Patients With High-Risk Oral Leukoplakia
Nivolumab for Patients With High-Risk Oral Leukoplakia Open
Importance Proliferative verrucous leukoplakia (PVL) is an aggressive oral precancerous disease characterized by a high risk of transformation to invasive oral squamous cell carcinoma (OSCC), and no therapies have been shown to affect its …
View article: Dental evaluation and clearance prior to allogeneic hematopoietic cell transplantation
Dental evaluation and clearance prior to allogeneic hematopoietic cell transplantation Open
Introduction Dental examination and stabilization are performed prior to allogeneic hematopoietic cell transplantation to decrease infection risk during neutropenia. Burden of dental disease and treatment need is not well characterized in …
View article: Editorial: Oral complications in cancer patients
Editorial: Oral complications in cancer patients Open
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View article: Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022
Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022 Open
Disclaimer This article is based on recommendations from the 12 th WALT Congress, Nice, October 3-6, 2018, and a follow-up review of the existing data and the clinical observations of an international multidisciplinary panel of clinicians …
View article: Immune checkpoint inhibitors in cancer therapy: Review of orofacial adverse events and role of the oral healthcare provider
Immune checkpoint inhibitors in cancer therapy: Review of orofacial adverse events and role of the oral healthcare provider Open
Immune checkpoint inhibitors (ICIs) are a revolutionary class of antineoplastic therapy that restore anti-tumor immunity. Consequences of this enhanced immune response include a multitude of immune related adverse events (irAEs) that can a…
View article: An Overview of Clinical Oncology and Impact on Oral Health
An Overview of Clinical Oncology and Impact on Oral Health Open
As the incidence of cancer continues to increase, so too will the use of various forms of cancer therapeutics and their associated oral and dental complications. Although many of the acute and chronic oral toxicities of cancer therapy are …
View article: Dental Caries Postradiotherapy in Head and Neck Cancer
Dental Caries Postradiotherapy in Head and Neck Cancer Open
Background: Treatment for head and neck cancer (HNC) such as radiotherapy (RT) can lead to numerous acute and chronic head and neck sequelae, including dental caries. The goal of the present study was to measure 2-y changes in dental carie…
View article: A Review of Oral Chronic Graft-Versus-Host Disease: Considerations for dental hygiene practice.
A Review of Oral Chronic Graft-Versus-Host Disease: Considerations for dental hygiene practice. Open
Purpose: Allogeneic hematopoietic cell transplantation (alloHCT), also known as stem cell or bone marrow transplantation, is a cellular therapy performed to treat a variety of malignant and non-malignant hematologic diseases. Chronic graft…