Explanipedia

Rhodococcus equi Endocarditis in Prosthetic Valve of a Heart Transplant Recipient Open

Siddartha Guru, Omaima Ali, Nadim Jaafar, Rahul Sharma, Navjot Guru , et al. · 2025

SOX2 commands LIM homeobox transcription factors in choroid plexus development and tumorigenesis Open

Lukas Faltings, Fengjuan Lin, Mariam Zahran, Heena Jalili, Anjali Siluveru , et al. · 2025

Background Choroid plexus (CP) tumors are rare brain neoplasms that mainly affect the pediatric population. Unlike benign CP papilloma (CPP), CP carcinoma (CPC) is an aggressive cancer with a dismal survival rate. Despite chromosome-wide r…

A Dilemma in the Diagnosis of Group A Streptococcus (GAS) Meningitis Versus Drug-Induced Aseptic Meningitis: A Case Report Open

Rahul Sharma, Nadim Jaafar, Navjot Guru, Esther S. Oh, Siddartha Guru · 2025

Group A Streptococcus (GAS), also called Streptococcus pyogenes, is a rare cause of adult meningitis. In recent years, many outbreaks of invasive S. pyogenes infections in Europe, involving the emm1.0 subtype of…

A Neurological Manifestation of Anaplasmosis: A Case Report Open

Siddartha Guru, Marvi Mahar, Navjot Guru, Leslie J. Parent · 2025

Mycobacterium kansasii chronic olecranon bursitis: A rare case report and literature review Open

Siddartha Guru, Jyoti Saroya, Navjot Guru, Peng Bai · 2025

Non-tuberculous mycobacteria are a rare cause of olecranon bursitis. We present a case of a 65-year-old man with history of chronic olecranon bursitis status post bursectomy two years prior, presented with two weeks of right elbow swelling…

Emphysematous osteomyelitis: A rare case report Open

Siddartha Guru, Navjot Guru, Rezhan Hussein · 2025

ETMR-26. MIR-34/449 FAMILY PLAYS A CRUCIAL ROLE IN CHOROID PLEXUS MULTICILIATION AND TUMORIGENESIS Open

Navjot Guru, Ahnaf Zaman, Maheen Umer, Mariam Zahran, Anjali Siluveru , et al. · 2024

BACKGROUND Choroid plexus (CP), an epithelial structure within the brain ventricles, produces cerebrospinal fluid and serves barrier functions in the brain. Primary CP neoplasms are rare intracranial tumors that predominantly occurs in chi…

ETMR-24. SOX2 INFLUENCES IDENTITY OF GLIA-LIKE PROGENITORS AND TUMORIGENESIS IN CHOROID PLEXUS THROUGH LIM HOMEODOMAIN TRANSCRIPTION FACTORS Open

Lukas Faltings, Mariam Zahran, Heena Jalili, Kristen Green, James Q. Virga , et al. · 2024

Choroid plexus (CP) tumors encompass a spectrum of rare brain neoplasms ranging from benign papilloma (CPP) to aggressive carcinoma (CPC) that collectively affect the pediatric population. Poor outcomes for high-grade lesions and side effe…

Data from Targeted Brain Tumor Radiotherapy Using an Auger Emitter Open

Giacomo Pirovano, Stephen A. Jannetti, Lukas M. Carter, Ahmad Sadique, Susanne Kossatz , et al. · 2023

Purpose:Glioblastoma multiforme is a highly aggressive form of brain cancer whose location, tendency to infiltrate healthy surrounding tissue, and heterogeneity significantly limit survival, with scant progress having been made in recent d…

Supplemental Material from Targeted Brain Tumor Radiotherapy Using an Auger Emitter Open

Giacomo Pirovano, Stephen A. Jannetti, Lukas M. Carter, Ahmad Sadique, Susanne Kossatz , et al. · 2023

Supplemental data

Data from Targeted Brain Tumor Radiotherapy Using an Auger Emitter Open

Giacomo Pirovano, Stephen A. Jannetti, Lukas M. Carter, Ahmad Sadique, Susanne Kossatz , et al. · 2023

Purpose:Glioblastoma multiforme is a highly aggressive form of brain cancer whose location, tendency to infiltrate healthy surrounding tissue, and heterogeneity significantly limit survival, with scant progress having been made in recent d…

Supplemental Material from Targeted Brain Tumor Radiotherapy Using an Auger Emitter Open

Giacomo Pirovano, Stephen A. Jannetti, Lukas M. Carter, Ahmad Sadique, Susanne Kossatz , et al. · 2023

Supplemental data

Dynamics of horizontal walking and vertical climbing in the Australian green tree frog (Ranoidea caerulea) Open

Melody W. Young, Nicholas D. Flaim, Johnathan R. Yarbro, Ashwin Ragupathi, Navjot Guru , et al. · 2023

Despite the high mechanical demands associated with climbing, the ability to ascend vertically has evolved independently in most major animal lineages. However, little is known about the kinetics, mechanical energy profiles or spatiotempor…

CCDC 2109920: Experimental Crystal Structure Determination Open

Christopher Wittmann, Anastasiia S. Sivchenko, Felix Bacher, Kelvin K. H. Tong, Navjot Guru , et al. · 2022

CCDC 2109919: Experimental Crystal Structure Determination Open

Christopher Wittmann, Anastasiia S. Sivchenko, Felix Bacher, Kelvin K. H. Tong, Navjot Guru , et al. · 2022

CCDC 2109921: Experimental Crystal Structure Determination Open

Christopher Wittmann, Anastasiia S. Sivchenko, Felix Bacher, Kelvin K. H. Tong, Navjot Guru , et al. · 2022

Inhibition of Microtubule Dynamics in Cancer Cells by Indole-Modified Latonduine Derivatives and Their Metal Complexes Open

Christopher Wittmann, Anastasiia S. Sivchenko, Felix Bacher, Kelvin K. H. Tong, Navjot Guru , et al. · 2022

Indolo[2,3-d]benzazepines (indololatonduines) are rarely discussed in the literature. In this project, we prepared a series of novel indololatonduine derivatives and their Ru^II and Os^II complexes and investigat…

A CLINICAL STUDY ON CHRONIC VENOUS INSUFFICIENCY WITH CHRONIC NON HEALING VENOUS ULCER IN A RETROVIRAL POSITIVE PATIENT Open

Navjot Guru · 2021

Venous ulcers are wounds which are the most serious and chronic complications in venous insufficiency, caused due to the inappropriate venous valves functioning and when these veins get damaged/ruptured due to any trauma, the pressure in t…

PARP-Targeted Auger Therapy in p53 Mutant Colon Cancer Xenograft Mouse Models Open

Thomas C. Wilson, Giacomo Pirovano, Gu Xiao, Zachary V. Samuels, Sheryl Roberts , et al. · 2021

Despite Auger electrons being highly appealing due to their short-range and high linear energy transfer to surrounding tissues, the progress in the field has been limited due to the challenge in delivering a therapeutic dose within the clo…

A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer Open

Paula Demétrio De Souza França, Susanne Kossatz, Christian Brand, Daniella K. Zanoni, Sheryl Roberts , et al. · 2021

A Phase I Study of a PARP1-targeted Topical Fluorophore for the Detection of Oral Cancer Open

Paula Demétrio De Souza França, Susanne Kossatz, Christian Brand, Daniella K. Zanoni, Sheryl Roberts , et al. · 2021

Background. Visual inspection and biopsy is the current standard of care for oral cancer diagnosis, but is subject to misinterpretation and consequently to misdiagnosis. Topically applied PARPi-FL is a molecularly specific, fluorescent con…

[18F]PARPi Imaging Is Not Affected by HPV Status In Vitro Open

Navjot Guru, Paula Demétrio De Souza França, Giacomo Pirovano, Cien Huang, Snehal G. Patel , et al. · 2021

Background. Human papillomavirus- (HPV-) associated oropharyngeal squamous cell carcinomas (OPSCCs) are clinically and pathologically distinct from HPV-negative tumors. Here, we explore whether HPV affects functional biomarkers, including …

Bimodal Imaging of Mouse Peripheral Nerves with Chlorin Tracers Open

Junior Gonzales, Javier Hernández‐Gil, Thomas C. Wilson, Dauren Adilbay, Mike Cornejo , et al. · 2021

Almost 17 million Americans have a history of cancer, a number expected to reach over 22 million by 2030. Cancer patients often undergo chemotherapy in the form of antineoplastic agents such as cis-platin and paclitaxel. Though effe…

Poly(ADP-ribose)polymerase1: A potential molecular marker to identify cancer during colposcopy procedures. Open

Paula Demétrio De Souza França, Navjot Guru, Abigail R. Kostolansky, Audrey Mauguen, Giacomo Pirovano , et al. · 2020

Despite efforts in prevention, cervical cancer still presents with a high worldwide incidence and remains a great problem in public health, especially in low-income countries. Screening programs, such as colposcopy with Papanicolaou testin…

A Phase I Study of a PARP1-targeted Topical Fluorophore for the Detection of Oral Cancer Open

Paula Demétrio De Souza França, Susanne Kossatz, Christian Brand, Daniella K. Zanoni, Sheryl Roberts , et al. · 2020

Purpose Visual inspection and biopsy is the current standard of care for oral cancer diagnosis, but is subject to misinterpretation and consequently to misdiagnosis. Topically applied PARPi-FL is a molecularly specific, fluorescent contras…

Fluorescence-guided resection of tumors in mouse models of oral cancer Open

Paula Demétrio De Souza França, Navjot Guru, Sheryl Roberts, Susanne Kossatz, Christian Mason , et al. · 2020

Improved radiosynthesis of 123I-MAPi, an auger theranostic agent Open

Thomas C. Wilson, Stephen A. Jannetti, Navjot Guru, Nagavarakishore Pillarsetty, Thomas Reiner , et al. · 2020

Here, we have developed an improved radiosynthesis of ¹²³I-MAPi, an Auger theranostic agent. This process was achieved using a single step, ¹²³I-iododestannylation reaction from the corresponding stannane precursor in…

Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization Open

Junior Gonzales, Giacomo Pirovano, Chun Yuen Chow, Paula Demétrio De Souza França, Lukas M. Carter , et al. · 2020

Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization Open

Junior Gonzales, Giacomo Pirovano, Chun Yuen Chow, Paula Demétrio De Souza França, Lukas M. Carter , et al. · 2020

Background Accidental peripheral nerve injury during surgical intervention results in a broad spectrum of potentially debilitating side effects. Tissue distortion and poor visibility can significantly increase the risk of nerve injury with…

Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization Open

Junior Gonzales, Giacomo Pirovano, Chun Yuen Chow, Paula Demétrio De Souza França, Lukas M. Carter , et al. · 2020

Purpose Accidental peripheral nerve injury during surgical intervention results in a broad spectrum of potentially debilitating side effects. Tissue distortion and poor visibility can significantly increase the risk of nerve injury with lo…

Navjot Guru YOU? Author Swipe