Nawal S. Gouda
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View article: Resveratrol Alleviates Aflatoxin B1-induced Renal Cortex Oxidative Stress and Apoptosis in Adult Male Albino Rats
Resveratrol Alleviates Aflatoxin B1-induced Renal Cortex Oxidative Stress and Apoptosis in Adult Male Albino Rats Open
Background: Aflatoxin B1 (AFB1) is a mycotoxin generated by the fungi Aspergillus flavus and Aspergillus parasiticus , known for its potential to cause liver cancer and has been associated with several adverse health effects. It commonly c…
View article: Evaluating the Linkage Between Resistin and Viral Seropositivity in Psoriasis: Evidence from a Tertiary Centre
Evaluating the Linkage Between Resistin and Viral Seropositivity in Psoriasis: Evidence from a Tertiary Centre Open
Psoriasis, a chronic immune-mediated inflammatory skin disorder, presents complex pathogenetic mechanisms potentially influenced by viral infections. This comprehensive study explored the possible interplay of resistance and viral infectio…
View article: Molecular dynamics of inflammation resolution: therapeutic implications
Molecular dynamics of inflammation resolution: therapeutic implications Open
Inflammation is a critical part of innate immune response that is essential for exclusion of harmful stimuli and restoration of tissue homeostasis. Nonetheless, failure to resolve inflammation results in chronic inflammatory conditions, in…
View article: Immunohistochemical Expression of IMP3 in Colorectal Adenocarcinoma: A Retrospective Analysis of Its Relation to Metastasis, Recurrence, and Prognosis
Immunohistochemical Expression of IMP3 in Colorectal Adenocarcinoma: A Retrospective Analysis of Its Relation to Metastasis, Recurrence, and Prognosis Open
Objectives: The protein Insulin-like growth factor II mRNA-binding protein 3 (IMP3) maintains mRNA stability thus enabling cellular multiplication as well as cell movement. The medical community links tumor progression in different maligna…
View article: Healthcare associated infection in maternity and pediatric hospital, Arar, Saudi Arabia
Healthcare associated infection in maternity and pediatric hospital, Arar, Saudi Arabia Open
Introduction: Healthcare-associated infections (HAIs) are avoidable complications from health care of health care, result in significant patient morbidity and mortality) and prolong the duration of hospital stay and economic cost.It used a…
View article: The Association of the mazEF Toxin-antitoxin System and Vancomycin Resistance in Clinical Isolates of Vancomycin Resistant Enterococcus faecalis
The Association of the mazEF Toxin-antitoxin System and Vancomycin Resistance in Clinical Isolates of Vancomycin Resistant Enterococcus faecalis Open
Vancomycin resistant enterococci are challenging bacteria as they are difficult to be eradicated. Toxin-antitoxin (TA) systems are genetic elements located in most prokaryotic genomes. The mazEF TA system is harbored by a plasmid among Ent…
View article: Hair Follicle-Related MicroRNA-34a Serum Expression and rs2666433A/G Variant in Patients with Alopecia: A Cross-Sectional Analysis
Hair Follicle-Related MicroRNA-34a Serum Expression and rs2666433A/G Variant in Patients with Alopecia: A Cross-Sectional Analysis Open
Alopecia areata (AA) is a type of immune-mediated alopecia. Recent studies have suggested microRNAs’ (miRNAs) implication in several cellular processes, including epidermal and hair follicle biology. Single nucleotide polymorphisms (SNPs) …
View article: MYD88, NFKB1, and IL6 transcripts overexpression are associated with poor outcomes and short survival in neonatal sepsis
MYD88, NFKB1, and IL6 transcripts overexpression are associated with poor outcomes and short survival in neonatal sepsis Open
View article: Impact of cytotoxic T‐lymphocyte‐associated protein 4 codon 17 variant and expression on vitiligo risk
Impact of cytotoxic T‐lymphocyte‐associated protein 4 codon 17 variant and expression on vitiligo risk Open
Background Cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) is one of the essential brakes expressed on T cells that prevent T‐cell hyperactivation‐associated autoimmune disorders. Several CTLA4 polymorphisms were implicated in the reg…
View article: Association of microRNA 17 host gene variant (rs4284505) with susceptibility and severity of systemic lupus erythematosus
Association of microRNA 17 host gene variant (rs4284505) with susceptibility and severity of systemic lupus erythematosus Open
Objective MicroRNAs are large family clusters of small noncoding RNAs that implicated in genetic and epigenetic regulation of several immunological processes and pathways. As an epigenetic modifier, the microRNA 17‐92 cluster host gene (MI…
View article: Healthcare Associated Infections Caused by Gram-negative Bacilli in Adult Intensive Care Units: Identification of AmpC Beta-Lactamases Mediated Antimicrobial Resistance
Healthcare Associated Infections Caused by Gram-negative Bacilli in Adult Intensive Care Units: Identification of AmpC Beta-Lactamases Mediated Antimicrobial Resistance Open
Background: Healthcare associated infections (HAIs) caused by AmpC β-lactamases producers are clinically significant as they can mediate resistance to cephalosporins, penicillins, monobactams and cephamycins. Objectives: To find out the pr…
View article: Prevalence of Multidrug Resistant Uropathogenic E. coli: Role of β-lactamase
Prevalence of Multidrug Resistant Uropathogenic E. coli: Role of β-lactamase Open
Urinary tract infection (UTI) is one of the most frequent health problems in clinical settings. E. coli is the most prevalent organism causing both community as well as hospital acquired UTI. Uropathogenic E. coli shows increasing rates of…
View article: In vitro Susceptibility of Multidrug-Resistant Klebsiella pneumoniae Isolates from an Egyptian Tertiary Care Hospital to Tigecycline and Colistin
In vitro Susceptibility of Multidrug-Resistant Klebsiella pneumoniae Isolates from an Egyptian Tertiary Care Hospital to Tigecycline and Colistin Open
The evolution of multidrug-resistant (MDR) Klebsiella pneumoniae constitutes a foremost public health issue, owing to the relatively limited antibiotic arsenal. Thereby, this research was undertaken to explore the in vitro susceptibility o…
View article: Acute Invasive Fungal Rhino-sinusitis: Clinical, Microbiological and Pathological Diagnosis
Acute Invasive Fungal Rhino-sinusitis: Clinical, Microbiological and Pathological Diagnosis Open
View article: PCR-detected fungal infection is associated with fatal outcomes in cirrhotic patients with spontaneous peritonitis
PCR-detected fungal infection is associated with fatal outcomes in cirrhotic patients with spontaneous peritonitis Open
The rate of mortality from Spontaneous Peritonitis (SP) in cirrhotic patients is still high despite the development of new antibiotic treatments and intensive hospital care. The coexistence of spontaneous fungal peritonitis (SFP) is almost…
View article: Risk Factors of Colorectal Cancer; A Case-Control Study
Risk Factors of Colorectal Cancer; A Case-Control Study Open
Background: Colorectal cancer is one of the commonest malignant tumors worldwide.Life style factors may contribute to the etiology of colorectal cancer as they are modifiable.A better understanding of the associations between lifestyle rel…