Nazish Jaffar
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View article: Benchmarking Pathology Foundation Models for Predicting Microsatellite Instability in Colorectal Cancer Histopathology
Benchmarking Pathology Foundation Models for Predicting Microsatellite Instability in Colorectal Cancer Histopathology Open
View article: Knowledge, attitudes, and practices regarding personal care products and their perceived link to breast cancer: a cross-sectional study
Knowledge, attitudes, and practices regarding personal care products and their perceived link to breast cancer: a cross-sectional study Open
View article: Spectrum of Colorectal Carcinoma in Karachi
Spectrum of Colorectal Carcinoma in Karachi Open
Background: Worldwide, colorectal carcinoma is the third most common malignancy affecting both males and females. Although being considered an old-age disease, a higher incidence of CRC has been reported in younger individuals in developin…
View article: Vaping—An Emerging Threat to Youngsters of Pakistan
Vaping—An Emerging Threat to Youngsters of Pakistan Open
View article: Consultation Liaison Psychiatry in a Tertiary Care Hospital
Consultation Liaison Psychiatry in a Tertiary Care Hospital Open
Background: Consultation-liaison psychiatry (CLP) is a subspecialty that bridges the gap between psychiatry and general medicine, managing the psychiatric needs of patients with physical illnesses in hospital settings. It plays a crucial r…
View article: Beyond bacteria: Role of non-bacterial gut microbiota species in inflammatory bowel disease and colorectal cancer progression
Beyond bacteria: Role of non-bacterial gut microbiota species in inflammatory bowel disease and colorectal cancer progression Open
This letter emphasizes the need to expand discussions on gut microbiome’s role in inflammatory bowel disease (IBD) and colorectal cancer (CRC) by including the often-overlooked non-bacterial components of the human gut flora. It highlights…
View article: Facilitators and barriers in acceptance of telemedicine among healthcare providers in Pakistan: A cross-sectional survey
Facilitators and barriers in acceptance of telemedicine among healthcare providers in Pakistan: A cross-sectional survey Open
Objectives: This study aimed to assess healthcare professionals’ awareness and acceptance of telemedicine residing in Pakistan. Materials and Methods: A cross-sectional study was conducted across Pakistan from November 2021 to March 2022. …
View article: Histopathological Study and Clinical Correlation of Glial Tumors at a Tertiary Care Hospital of Karachi
Histopathological Study and Clinical Correlation of Glial Tumors at a Tertiary Care Hospital of Karachi Open
Objective: To observe the spectrum of glial tumors in a resource-limited tertiary care setup of Karachi according to the modified WHO central nervous system tumor classification.Study Design:A retrospective analysis.Place and Duration of S…
View article: Spectrum of Flat Epithelial Atypia in Breast Lesions
Spectrum of Flat Epithelial Atypia in Breast Lesions Open
Objective: To determine the frequency of flat epithelial atypia and its association with breast lesions in trucut biopsies and lumpectomy specimens in the local population.Study Design: A cross-sectional study.Place and Duration of Study: …
View article: Use of a Novel Deep Learning Open-Source Model for Quantification of Ki-67 in Breast Cancer Patients in Pakistan: A Comparative Study between the Manual and Automated Methods
Use of a Novel Deep Learning Open-Source Model for Quantification of Ki-67 in Breast Cancer Patients in Pakistan: A Comparative Study between the Manual and Automated Methods Open
Introduction: Breast cancer is the most common cancer in women; its early detection plays a crucial role in improving patient outcomes. Ki-67 is a biomarker commonly used for evaluating the proliferation of cancer cells in breast cancer pa…
View article: Diagnostic Performance of Direct Microscopic Techniques and Culture Media for Fungal Isolates from Hair Specimens
Diagnostic Performance of Direct Microscopic Techniques and Culture Media for Fungal Isolates from Hair Specimens Open
Objective: To compare the diagnostic performance of direct microscopic techniques and culture media for detecting fungal isolates in hair specimens.Study Design: Cross-sectional study.Place and Duration of Study: The study was conducted at…
View article: Ki-67 Quantification in Breast Cancer by Digital Imaging AI Software and its Concordance with Manual Method
Ki-67 Quantification in Breast Cancer by Digital Imaging AI Software and its Concordance with Manual Method Open
Artificial intelligence, Algorithms, Breast cancer, Deep learning, Image detection, Ki-67.
View article: Knowledge of Diabetes Mellitus among Undergraduate Clinical Students of Sindh Medical College
Knowledge of Diabetes Mellitus among Undergraduate Clinical Students of Sindh Medical College Open
Objective: To determine the knowledge of undergraduate students of Sindh Medical College regarding Diabetes Mellitus (DM) Methodology: This cross sectional study was conducted at Sindh Medical College, Jinnah Sindh Medical University (SMC-…
View article: Association of Abnormal Coagulation Tests in Dengue Fever with Clinical Outcomes of The Patients
Association of Abnormal Coagulation Tests in Dengue Fever with Clinical Outcomes of The Patients Open
Objective: To assess the coagulation test abnormalities (prothrombin time, activated partial thromboplastin time and fibrin degradation products) in dengue fever patients and its impact on clinical outcomes of the patient.
Study Design: C…
View article: Evaluation of Chromosomal Abnormalities in Acute Myeloid Leukemia (AML) and Acute Lymphoid Leukemia (ALL)
Evaluation of Chromosomal Abnormalities in Acute Myeloid Leukemia (AML) and Acute Lymphoid Leukemia (ALL) Open
Background: The present study evaluated the chromosomal and molecular variations in patients of acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). Methods and Materials: A cross-sectional study was conducted at the Department …
View article: Role of Platelet-Rich Plasma and Adipose-Derived Stem Cells in the Treatment of Spinal Cord Injury: A Case Report
Role of Platelet-Rich Plasma and Adipose-Derived Stem Cells in the Treatment of Spinal Cord Injury: A Case Report Open
Autologous platelet-rich plasma (PRP) and adipose tissues have proven beneficial in treating diabetic ulcer, eye infections, cataracts, and dermatologic conditions. We treated a patient with spinal cord injury with two consecutive platelet…
View article: Correlation of Hand Hygiene Knowledge and Hand Decontamination Practices of Medical Students
Correlation of Hand Hygiene Knowledge and Hand Decontamination Practices of Medical Students Open
Objectives: To determine the knowledge of MBBS students of a public sector medical university regarding hand hygiene and to assess the practical implication of their knowledge regarding hand hygiene during the clinical postings. Study Desi…
View article: Evaluation of Naked Eye Single Tube Red Cell Osmotic Fragility Test (NESTROFT) in Screening and Diagnosis of Beta Thalassaemia Trait in Pakistani Population
Evaluation of Naked Eye Single Tube Red Cell Osmotic Fragility Test (NESTROFT) in Screening and Diagnosis of Beta Thalassaemia Trait in Pakistani Population Open
Background: Beta thalassaemia is an inherited disease that is a cause of continuous burden on the affected families and the society. The objective of the study was to evaluate the efficacy of Naked Eye Single Tube Red Cell Osmotic Fragilit…
View article: Knowledge, Attitude and Practices of Pharmaceutical Waste Disposal in Community Pharmacies of Karachi
Knowledge, Attitude and Practices of Pharmaceutical Waste Disposal in Community Pharmacies of Karachi Open
Objectives: The aim of the study was to assess the knowledge of community pharmacies about recommended methods of drug disposal and hazardous effects of improper disposal of pharmaceutical waste and to determine the attitude as well as pra…
View article: Evaluation of Acute and Chronic Antidiabetic Activity of Ivy (Hedera helix L.) Aqueous Leaf Extract in Rat Model
Evaluation of Acute and Chronic Antidiabetic Activity of Ivy (Hedera helix L.) Aqueous Leaf Extract in Rat Model Open
The histopathological studies of vital organs revealed protective effect of ivy via maintaining the normal architecture as compared to alloxan model. Hence, our findings support the potential use of ivy for diabetes management.
View article: A web-based health education module and its impact on the preventive practices of health-care workers during the COVID-19 pandemic
A web-based health education module and its impact on the preventive practices of health-care workers during the COVID-19 pandemic Open
Proper training on the preventive measures against COVID-19 among health-care workers is crucial for mitigating the spread of viral infection. The present study evaluated the efficacy of a brief web-based module on the practice of hand hyg…
View article: Morphological Spectrum of Gall Bladder Diseases at A Tertiary Care Hospital of Karachi
Morphological Spectrum of Gall Bladder Diseases at A Tertiary Care Hospital of Karachi Open
Objectives: To determine morphological spectrum of gall bladder diseases at a tertiary care centre of Karachi and to correlate with age and gender Methodology: Data was collected from histopathological records between June 2017 to June 201…
View article: High Risk Human Papilloma Virus Genotype Distribution in Cervical Intraepithelial and Invasive Carcinoma
High Risk Human Papilloma Virus Genotype Distribution in Cervical Intraepithelial and Invasive Carcinoma Open
Background: High-risk (HR) Human Papillomavirus (HPV) is an established cause of cervical cancer. HPV genotype detection is significant in preventing cervical cancers through targeted vaccination our study aimed to identify HRHPV16/18 and …
View article: Trend of Regular Voluntary Blood Donation and its Associated Factors in Karachi - A Comparative Analysis of Medical and Non-medical Undergraduate Students
Trend of Regular Voluntary Blood Donation and its Associated Factors in Karachi - A Comparative Analysis of Medical and Non-medical Undergraduate Students Open
Background: Regular voluntary unpaid blood donation assures safe blood supply in association with minimum infection transmission. The purpose of this study was to identify the frequency of regular voluntary blood donation and to evaluate t…
View article: Rise of Blood Borne Infections in Pakistan. Is it a Call for Action
Rise of Blood Borne Infections in Pakistan. Is it a Call for Action Open
Health care workers are exposed to a number of occupational hazards including injury from needle stick, which puts workers at risk of transmission of as many as 30 pathogens, of which the most life-threatening are the Hepatitis B virus (HB…
View article: Spectrum of Tp53 gene mutation in basal cell carcinoma and its morphological subtypes in people of color.
Spectrum of Tp53 gene mutation in basal cell carcinoma and its morphological subtypes in people of color. Open
Objectives: Basal cell carcinoma (BCC) is the most common cutaneous malignancy in white population. The pattern of exon specific p53 mutations in BCC and its subtypes remain undetected in our population. This study was designed to evaluate…