Neal L. Benowitz
YOU?
Author Swipe
View article: E-Cigarettes in Historical Context—Innovation, Risk, and Regulation
E-Cigarettes in Historical Context—Innovation, Risk, and Regulation Open
This Viewpoint discusses the potential for e-cigarettes to displace smoking, restrictive regulations, and public misperceptions amid enduring nicotine demand and persistent smoking-related disease.
View article: Corrigendum to Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial
Corrigendum to Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial Open
View article: Urinary Tobacco and Nicotine Exposure Biomarkers as Predictors of Transitions between Cigarette and e-Cigarette Use in the Exhale Longitudinal Cohort Study
Urinary Tobacco and Nicotine Exposure Biomarkers as Predictors of Transitions between Cigarette and e-Cigarette Use in the Exhale Longitudinal Cohort Study Open
Introduction Urinary tobacco and nicotine exposure biomarkers may be predictive of subsequent transitions in product use. Methods We used data from an observational study of 371 adults who smoked cigarettes daily, some of whom also used e-…
View article: Theoretical and retrograde calculation of blood alcohol: wide estimates using the Academy Standards Board for calculations over an extended period of time
Theoretical and retrograde calculation of blood alcohol: wide estimates using the Academy Standards Board for calculations over an extended period of time Open
Introduction Toxicologists defend alcohol testing from their laboratories for medicolegal cases. Methods A 22-year-old woman drank 144.1 g of alcohol over 8.25 hours at work. Precise details of her drinking (time, volume, and alcohol conte…
View article: Caffeine, nicotine, cannabis, and psilocybin: Pharmacology, toxicology, and potential therapeutic uses of four naturally occurring psychoactive substances
Caffeine, nicotine, cannabis, and psilocybin: Pharmacology, toxicology, and potential therapeutic uses of four naturally occurring psychoactive substances Open
Psychoactive substances are compounds that can influence perception, consciousness, cognition, and emotions. The psychoactive substances caffeine, nicotine, cannabis, and psilocybin all originate from natural sources and can be used withou…
View article: Canadian Cardiovascular Society Clinical Practice Update on Contemporary Approaches to Smoking Cessation
Canadian Cardiovascular Society Clinical Practice Update on Contemporary Approaches to Smoking Cessation Open
View article: Cytisinicline for Smoking Cessation
Cytisinicline for Smoking Cessation Open
Importance New smoking cessation medication options are needed. Cytisinicline, a partial agonist at α4β2 nicotinic acetylcholine receptors, has demonstrated smoking cessation efficacy in 1 US trial. Additional evidence is needed. Objective…
View article: Tobacco Biomarkers by Latino Heritage and Race, US, 2007 to 2014 National Health and Nutrition Examination Survey
Tobacco Biomarkers by Latino Heritage and Race, US, 2007 to 2014 National Health and Nutrition Examination Survey Open
Background: Tobacco biomarkers reflect smoking intensity and are used to assess cessation status. No study has evaluated variation by Latino heritage. Methods: Data from the 2007 to 2014 National Health and Nutrition Examination Survey wer…
View article: Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial
Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial Open
U.S. NIH/FDA U54DA03165.
View article: Cytisinicline for Vaping Cessation in Adults Using Nicotine E-Cigarettes
Cytisinicline for Vaping Cessation in Adults Using Nicotine E-Cigarettes Open
Importance The prevalence of e-cigarette use among US adults, especially young adults, is rising. Many would like to quit vaping nicotine but are unable to do so. Cytisinicline, a plant-based alkaloid, targets nicotinic acetylcholine recep…
View article: Menthol versus tobacco e-liquid flavor: Impact on acute subjective effects, puff patterns, and intentions for use among Black and White menthol smokers
Menthol versus tobacco e-liquid flavor: Impact on acute subjective effects, puff patterns, and intentions for use among Black and White menthol smokers Open
View article: Pharmacokinetics and Pharmacodynamics of Inhaled Nicotine Salt and Free-Base Using an E-cigarette: A Randomized Crossover Study
Pharmacokinetics and Pharmacodynamics of Inhaled Nicotine Salt and Free-Base Using an E-cigarette: A Randomized Crossover Study Open
Introduction Popular “pod-style” e-cigarettes commonly use nicotine salt-based e-liquids that cause less irritation when inhaled and can deliver higher nicotine concentrations than free-base nicotine. This study investigated the pharmacoki…
View article: Electronic hookah (waterpipe) vaping reduces vascular endothelial function: the role of nicotine
Electronic hookah (waterpipe) vaping reduces vascular endothelial function: the role of nicotine Open
Despite safety claims heavily advertised by the hookah tobacco industry, acute e-hookah vaping induces in vivo endothelial dysfunction by impairing ex vivo NO bioavailability associated with increased ROS production. These effects are attr…
View article: Nicotine Delivery and Changes in Withdrawal and Craving During Acute Electronic Cigarette, Heated Tobacco Product, and Cigarette Use Among a Sample of Black and White People Who Smoke
Nicotine Delivery and Changes in Withdrawal and Craving During Acute Electronic Cigarette, Heated Tobacco Product, and Cigarette Use Among a Sample of Black and White People Who Smoke Open
Introduction E-cigarettes and heated tobacco products (HTPs) may serve as potential options for harm reduction for smokers if they possess reward profiles similar to cigarettes. Little is known about the abuse liability of HTPs and e-cigar…
View article: Associations of Cannabis Use, High-Risk Alcohol Use, and Depressive Symptomology with Motivation and Attempts to Quit Cigarette Smoking Among Adults: Findings from the 2020 ITC Four Country Smoking and Vaping Survey
Associations of Cannabis Use, High-Risk Alcohol Use, and Depressive Symptomology with Motivation and Attempts to Quit Cigarette Smoking Among Adults: Findings from the 2020 ITC Four Country Smoking and Vaping Survey Open
This study assessed independent and interaction effects of the frequency of cannabis use, high-risk alcohol use, and depressive symptomology on motivation and attempts to quit cigarette smoking among adults who regularly smoked. Cross-sect…
View article: Association of non-daily hookah tobacco smoking and cardiovascular disease-related exposure biomarkers among U.S. users: The Population Assessment of Tobacco and Health Study
Association of non-daily hookah tobacco smoking and cardiovascular disease-related exposure biomarkers among U.S. users: The Population Assessment of Tobacco and Health Study Open
Hookah smoking has grown to become a global tobacco epidemic. While cigarette smoking is a well-established cardiovascular disease (CVD) risk factor, the CVD risks of hookah smoking are unknown, particularly among regular U.S. adult hookah…
View article: Society for Research on Nicotine and Tobacco as an Outgrowth of the 1988 Surgeon General’s Report on Nicotine Addiction: Reflections of the Early Presidents
Society for Research on Nicotine and Tobacco as an Outgrowth of the 1988 Surgeon General’s Report on Nicotine Addiction: Reflections of the Early Presidents Open
Introduction The Society for Research on Nicotine and Tobacco began in the United States as a scientific organization “to stimulate the generation and dissemination of new knowledge concerning nicotine and tobacco in all its manifestations…
View article: Cytisinicline for Smoking Cessation
Cytisinicline for Smoking Cessation Open
Importance Cytisinicline (cytisine) is a plant-based alkaloid that, like varenicline, binds selectively to α4β2 nicotinic acetylcholine receptors, which mediate nicotine dependence. Although not licensed in the US, cytisinicline is used in…
View article: Biomarkers of Toxic Exposure and Oxidative Stress Among U.S. Adult Users of Premium Cigar Versus Other Cigar Subtypes: 2013–2019
Biomarkers of Toxic Exposure and Oxidative Stress Among U.S. Adult Users of Premium Cigar Versus Other Cigar Subtypes: 2013–2019 Open
Introduction Cigars are currently the second-highest-used combustible tobacco product among U.S. adults, but knowledge about health effects of premium cigars versus other cigar subtype use is limited. Aims and Methods This study analyzed t…
View article: Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants
Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants Open
Starting in the 1970s, individuals, businesses and the public have increasingly benefited from policies prohibiting smoking indoors, saving thousands of lives and billions of dollars in healthcare expenditures. Smokefree policies to protec…
View article: Effects of dual use of e-cigarette and cannabis during adolescence on cigarette use in young adulthood
Effects of dual use of e-cigarette and cannabis during adolescence on cigarette use in young adulthood Open
Introduction E-cigarette and cannabis use by adolescents are risk factors for smoking initiation. We hypothesised that increasingly common dual use of e-cigarette and cannabis in adolescence leads to more frequent cigarette smoking in youn…
View article: Determining associations between co-use of tobacco & cannabis products and mental/behavioral health outcomes: a narrative literature analysis
Determining associations between co-use of tobacco & cannabis products and mental/behavioral health outcomes: a narrative literature analysis Open
Population Medicine considers the following types of articles:• Research Papers -reports of data from original research or secondary dataset analyses.• Review Papers -comprehensive, authoritative, reviews within the journal's scope.These i…
View article: Nicotine Intake in Adult Pod E-cigarette Users: Impact of User and Device Characteristics
Nicotine Intake in Adult Pod E-cigarette Users: Impact of User and Device Characteristics Open
Introduction This study examined user behavior, e-cigarette dependence, and device characteristics on nicotine intake among users of pod-mod e-cigarettes. Aims and Methods In 2019–2020, people who use pod-mods in the San Francisco Bay Area…
View article: Smoking cessation, harm reduction, and biomarkers protocols in the PhenX Toolkit: Tools for standardized data collection
Smoking cessation, harm reduction, and biomarkers protocols in the PhenX Toolkit: Tools for standardized data collection Open
View article: Supplementary Figure and Table from Genetic Variability of Smoking Persistence in African Americans
Supplementary Figure and Table from Genetic Variability of Smoking Persistence in African Americans Open
Supplementary Figure and Table from Genetic Variability of Smoking Persistence in African Americans
View article: Data from Genetic Variability of Smoking Persistence in African Americans
Data from Genetic Variability of Smoking Persistence in African Americans Open
To date, most genetic association analyses of smoking behaviors have been conducted in populations of European ancestry and many of these studies focused on the phenotype that measures smoking quantity, that is, cigarettes per day. Additio…
View article: Supplementary Figure and Table from Genetic Variability of Smoking Persistence in African Americans
Supplementary Figure and Table from Genetic Variability of Smoking Persistence in African Americans Open
Supplementary Figure and Table from Genetic Variability of Smoking Persistence in African Americans
View article: Data from Genetic Variability of Smoking Persistence in African Americans
Data from Genetic Variability of Smoking Persistence in African Americans Open
To date, most genetic association analyses of smoking behaviors have been conducted in populations of European ancestry and many of these studies focused on the phenotype that measures smoking quantity, that is, cigarettes per day. Additio…
View article: Supplementary Methods, Tables 1 - 5, Figures 1 - 3 from Comparison of Nicotine and Carcinogen Exposure with Water Pipe and Cigarette Smoking
Supplementary Methods, Tables 1 - 5, Figures 1 - 3 from Comparison of Nicotine and Carcinogen Exposure with Water Pipe and Cigarette Smoking Open
PDF file - 481K, Table S-1. SRM Transitions and Collision Energies Table S-2. Equations for Mercapturic Acid Calibration Curves Table S-3. Precision and Accuracy for Mercapturic Acids in Urine, Intra-day (N=6) Table S-4. Concentrations of …
View article: Supplementary Table 1 from Biochemical Estimation of Noncompliance with Smoking of Very Low Nicotine Content Cigarettes
Supplementary Table 1 from Biochemical Estimation of Noncompliance with Smoking of Very Low Nicotine Content Cigarettes Open
Supplementary Table 1. Biochemical Measures of Compliance: Data from Individual Subjects