N. Sharma
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View article: The Power of Emotional Intelligence in Healthcare: A Narrative Review of its Neurobiological Basis, Clinical Leadership and Patient-centric Care
The Power of Emotional Intelligence in Healthcare: A Narrative Review of its Neurobiological Basis, Clinical Leadership and Patient-centric Care Open
The multifaceted functioning of Emotional Intelligence (EI) in formal healthcare settings is a testament to quality healthcare delivery; the present paper examines its neurophysiological bases, its role in clinical leadership, dynamic team…
View article: "Effects OF Tabata Training ON Atherogenic Index, Hba1c AND Waist Circumference IN Adults WITH Type 2 Diabetes Mellitus: A Randomized Controlled Trial"
"Effects OF Tabata Training ON Atherogenic Index, Hba1c AND Waist Circumference IN Adults WITH Type 2 Diabetes Mellitus: A Randomized Controlled Trial" Open
Type 2 diabetes mellitus (T2DM) is a multifactorial and long term complication which has been the leading cause of several complications including cardiovascular disease, neuropathy, and nephropathy globally. Nonetheless previous structure…
View article: Snowpark: Performant, Secure, User-Friendly Data Engineering and AI/ML Next To Your Data
Snowpark: Performant, Secure, User-Friendly Data Engineering and AI/ML Next To Your Data Open
Snowflake revolutionized data analytics with an elastic architecture that decouples compute and storage, enabling scalable solutions supporting data architectures like data lake, data warehouse, data lakehouse, and data mesh. Building on t…
View article: Emergence of new systematics for open charm production in high energy collisions
Emergence of new systematics for open charm production in high energy collisions Open
A bstract We present the production systematics of open charm hadron yields in high-energy collisions and their description based on the Statistical Hadronization Model of charm (SHMc). The rapidity density of D 0 , D + , D *+ , $$ {D}_s^{…
View article: Transport coefficients of the heavy quark in the domain of the nonperturbative and noneikonal gluon radiation
Transport coefficients of the heavy quark in the domain of the nonperturbative and noneikonal gluon radiation Open
Drag and diffusion coefficients of the heavy quarks (HQs), such as charm and bottom, are one of the prime tools for discerning the properties of the deconfined quantum chromo-dynamics (QCD) medium created in heavy-ion collision experiments…
View article: Canonical treatment of strangeness and light nuclei production
Canonical treatment of strangeness and light nuclei production Open
The canonical effects on strangeness and light nuclei production in high energy collisions are investigated, with a particular focus on low multiplicity events observed in small collision systems at the Large Hadron Collider (LHC), and als…
View article: Transitioning into the Rural Clean Energy Issues in Developing Country: South Asian Perspectives
Transitioning into the Rural Clean Energy Issues in Developing Country: South Asian Perspectives Open
Background: Energy transitions are a key topic in emerging economies, driven by fuel price fluctuations, environmental concerns, technological advancements, and energy accessibility goals. South Asia faces challenges in achieving clean, su…
View article: TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling Open
Chromosomal instability (CIN) is common in solid tumours and fuels evolutionary adaptation and poor prognosis by increasing intratumour heterogeneity. Systematic characterization of driver events in the TRACERx non-small-cell lung cancer (…
View article: Comparative Study on Phase Imaging of X-Ray and Neutron Sources
Comparative Study on Phase Imaging of X-Ray and Neutron Sources Open
After the discovery of X-ray in 1895 the vast majority of radiographs have been taken and interpreted on the basis of absorption contrast of the object. In recent years the possibility of utilizing phase-contrast effect has received consid…
View article: Origins and impact of extrachromosomal DNA
Origins and impact of extrachromosomal DNA Open
View article: 78P Exploring ecDNA heterogeneity and evolution in non-small cell lung cancer
78P Exploring ecDNA heterogeneity and evolution in non-small cell lung cancer Open
View article: GESTURE RECOGNITION FOR TOUCH-FREE PC CONTROL USING A NEURAL NETWORK APPROACH
GESTURE RECOGNITION FOR TOUCH-FREE PC CONTROL USING A NEURAL NETWORK APPROACH Open
In the pursuit of advancing the field of touch-free human-computer interaction, this paper is focused on developing a gesture enabled PC control system that aims for enhancing user engagement and providing intuitive and flexible control me…
View article: Transport coefficients of the heavy quark in the domain of the non-perturbative and non-eikonal gluon radiation
Transport coefficients of the heavy quark in the domain of the non-perturbative and non-eikonal gluon radiation Open
Drag and diffusion coefficients of the Heavy Quarks (HQs), such as charm and bottom, are one of the prime tools for discerning the properties of the deconfined QCD medium created in the Heavy Ion Collisions experiments. The innate non-pert…
View article: Emergence of New Systematics for Open Charm Production in High Energy Collisions
Emergence of New Systematics for Open Charm Production in High Energy Collisions Open
We present the production systematics of open charm hadron yields in high-energy collisions and their description based on the Statistical Hadronization Model of charm (SHMc). The rapidity density of $D^0, D^+, D^{*+}, D_s^+$ mesons and $Λ…
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 3. Cytotoxic effects of NEO212 on primary glioma cells
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 4. NEO212 induces DNA damage in TMZ-sensitive and TMZ-resistant cells
View article: Data from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i>
Data from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i> Open
There is no effective therapy for breast cancer that has spread to the brain. A major roadblock is the blood–brain barrier (BBB), which prevents the usual breast cancer drugs from effectively reaching intracranial metastases. The alkylatin…
View article: Data from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Patients with glioblastoma multiforme (GBM), a malignant primary brain tumor, inevitably develop resistance to standard-of-care chemotherapy, temozolomide. This study explores the effects of the novel agent NEO212, a conjugate of temozolom…
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 5. U251 TR-resistant and LN229 TR2-resistant cells are MGMT-negative
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 6. PARP inhibitor is not cytotoxic to U251 cells
View article: Data from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i>
Data from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i> Open
There is no effective therapy for breast cancer that has spread to the brain. A major roadblock is the blood–brain barrier (BBB), which prevents the usual breast cancer drugs from effectively reaching intracranial metastases. The alkylatin…
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 5. U251 TR-resistant and LN229 TR2-resistant cells are MGMT-negative
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 4. NEO212 induces DNA damage in TMZ-sensitive and TMZ-resistant cells
View article: Supplementary Figures 1 - 6, Table 1 from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i>
Supplementary Figures 1 - 6, Table 1 from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i> Open
PDF file - 320K, Supplementary Table S1: Drug sensitivities of cells transfected with MGMT cDNA; Supplementary Figure S1: Chemical structure of T-P; Supplementary Figure S2: Colony formation after drug treatment; Supplementary Figure S3: H…
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 2. Quantitative evaluation of the effects of NEO212 on cytotoxicity
View article: Supplementary Figures 1 - 6, Table 1 from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i>
Supplementary Figures 1 - 6, Table 1 from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i> Open
PDF file - 320K, Supplementary Table S1: Drug sensitivities of cells transfected with MGMT cDNA; Supplementary Figure S1: Chemical structure of T-P; Supplementary Figure S2: Colony formation after drug treatment; Supplementary Figure S3: H…
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 7. Pathological evaluation of tissues following chronic treatment of NEO212
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 1. Chemical structure of NEO212.
View article: Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas
Data Supplement from NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas Open
Supplementary Figure 2. Quantitative evaluation of the effects of NEO212 on cytotoxicity
View article: Supplementary Figure Legends from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i>
Supplementary Figure Legends from A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells <i>In Vitro</i> and Intracranial Triple-Negative Tumor Growth <i>In Vivo</i> Open
PDF file - 72K