Nehal I. Abu‐Lail
YOU?
Author Swipe
View article: Cell Partitioning Design for Microfluidic ATPS Devices: A Dynamic Energy Strategy and Calculation Using Chondrocytes and Model Microparticles
Cell Partitioning Design for Microfluidic ATPS Devices: A Dynamic Energy Strategy and Calculation Using Chondrocytes and Model Microparticles Open
Sorting and isolating specific cells from heterogeneous populations are crucial for many biomedical applications, including drug discovery and medical diagnostics. Conventional methods such as Fluorescent Activated Cell Sorting (FACS) and …
View article: Phenotypic Characterization of pilA, pilB, and pilD Mutants of Acinetobacter baumannii 5075: Impacts on Growth, Biofilm Formation, and Tazobactam Response
Phenotypic Characterization of pilA, pilB, and pilD Mutants of Acinetobacter baumannii 5075: Impacts on Growth, Biofilm Formation, and Tazobactam Response Open
Background/Objectives: The Type IV pilus assembly system in Acinetobacter baumannii is a major determinant of its pathogenicity, playing a role in surface-associated functions via the biogenesis of Type IV pili (T4P). Tazobactam (TAZ) is a…
View article: Role of adhesion in the mechanics of pathogenic <i>Listeria monocytogenes</i> EGDe as a function of the <i>p</i>H of growth
Role of adhesion in the mechanics of pathogenic <i>Listeria monocytogenes</i> EGDe as a function of the <i>p</i>H of growth Open
Atomic force microscopy was utilized to estimate the adhesion strengths to silicon nitride as well as the cellular elasticities of pathogenic Listeria monocytogenes EGDe cells cultured in media adjusted to five different pH conditions of g…
View article: Impact of interstitial flow on cartilage matrix synthesis and NF‐kB transcription factor mRNA expression in a novel perfusion bioreactor
Impact of interstitial flow on cartilage matrix synthesis and NF‐kB transcription factor mRNA expression in a novel perfusion bioreactor Open
This work is focused on designing an easy‐to‐use novel perfusion system for articular cartilage (AC) tissue engineering and using it to elucidate the mechanism by which interstitial shear upregulates matrix synthesis by articular chondrocy…
View article: Forces Governing the Transport of Pathogenic and Nonpathogenic Escherichia coli in Nitrogen and Magnesium Doped Biochar Amended Sand Columns
Forces Governing the Transport of Pathogenic and Nonpathogenic Escherichia coli in Nitrogen and Magnesium Doped Biochar Amended Sand Columns Open
Background: Access to safe drinking water remains a global issue with fecal indicator bacteria being major pollutants. Biochars offer low-cost adsorbents for bacterial pathogens. A fundamental understanding of how biochars interact with ba…
View article: Interleukin 1β and lipopolysaccharides induction dictate chondrocyte morphological properties and reduce cellular roughness and adhesion energy comparatively
Interleukin 1β and lipopolysaccharides induction dictate chondrocyte morphological properties and reduce cellular roughness and adhesion energy comparatively Open
Osteoarthritis (OA) is a whole joint disease marked by the degradation of the articular cartilage (AC) tissue, chronic inflammation, and bone remodeling. Upon AC’s injury, proinflammatory mediators including interleukin 1β (IL1β) and lipop…
View article: From Chondrocytes to Chondrons, Maintenance of Phenotype and Matrix Production in a Composite 3D Hydrogel Scaffold
From Chondrocytes to Chondrons, Maintenance of Phenotype and Matrix Production in a Composite 3D Hydrogel Scaffold Open
Osteoarthritis (OA) is a degenerative disease characterized by articular cartilage (AC) degradation that affects more than 30 million people in the USA. OA is managed with symptom-alleviating medications. Matrix-assisted autologous chondro…
View article: <i>In vitro</i> effects of nutraceutical treatment on human osteoarthritic chondrocytes of females of different age and weight groups
<i>In vitro</i> effects of nutraceutical treatment on human osteoarthritic chondrocytes of females of different age and weight groups Open
The in vitro effects of four nutraceuticals, catechin hydrate, gallic acid, α-tocopherol and ascorbic acid, on the ability of human osteoarthritic chondrocytes of two female obese groups to form articular cartilage (AC) tissues and to redu…
View article: A Step Towards the Development of a Wet Cellular Bioengineering Laboratory
A Step Towards the Development of a Wet Cellular Bioengineering Laboratory Open
A Step towards the Development of a Wet Cellular Bioengineering Laboratory The cellular bioengineering course deals with how engineering concepts apply to varioustypes of cells. The goal of this study was to develop hands-on experimental m…
View article: Work in Progress:Development of Hands-on Desktop Learning Modules for Bioengineering Courses
Work in Progress:Development of Hands-on Desktop Learning Modules for Bioengineering Courses Open
Development of Hands-on Desktop Learning Modules for Bioengineering Courses – A Work in ProgressAbstractCurrent engineering courses heavily rely on traditional lectures to cover engineering concepts.The engineering education community, how…
View article: Variations in the Morphology, Mechanics and Adhesion of Persister and Resister E. coli Cells in Response to Ampicillin: AFM Study
Variations in the Morphology, Mechanics and Adhesion of Persister and Resister E. coli Cells in Response to Ampicillin: AFM Study Open
Persister bacterial cells are great at surviving antibiotics. The phenotypic means by which they do that are underexplored. As such, atomic force microscope (AFM) was used to quantify the contributions of the surface properties of the oute…
View article: Book of Abstracts: 4th International Congress on Health Sciences and Technology Organized by the School of Health Technology, Federal University of Technology (FUTO), Owerri, Imo State, Nigeria, 7-9 August, 2019
Book of Abstracts: 4th International Congress on Health Sciences and Technology Organized by the School of Health Technology, Federal University of Technology (FUTO), Owerri, Imo State, Nigeria, 7-9 August, 2019 Open
© 2019 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properl…
View article: Colloidal and rheological characterization of SWCNT in biological media
Colloidal and rheological characterization of SWCNT in biological media Open
We report on the colloidal and rheological characterization of suspensions of commercial single-walled carbon nanotubes (SWCNT) and oxidized single walled carbon nanotubes (SWCNT-oxi24h), in water and fetal bovine serum (FBS). The effects …
View article: Responses of <i>Acinetobacter baumannii</i> Bound and Loose Extracellular Polymeric Substances to Hyperosmotic Agents Combined with or without Tobramycin: An Atomic Force Microscopy Study
Responses of <i>Acinetobacter baumannii</i> Bound and Loose Extracellular Polymeric Substances to Hyperosmotic Agents Combined with or without Tobramycin: An Atomic Force Microscopy Study Open
In this work, contributions of extracellular polymeric substances (EPS) to the nanoscale mechanisms through which the multidrug-resistant Acinetobacter baumannii responds to antimicrobial and hyperosmotic treatments were investigated by at…
View article: Paenibacillus Naphthalenovorans Biofilms Interact with and Degrade Naphthalene as Observed using Various Microscopy Techniques
Paenibacillus Naphthalenovorans Biofilms Interact with and Degrade Naphthalene as Observed using Various Microscopy Techniques Open
The role of Paenibacillus naphthalenovorans biofilm formation in degrading a model polycyclic aromatic hydrocarbon (PAH) (naphthalene) was investigated via an array of microscopy techniques. The early stages of biofilm formation near a nap…
View article: The Effects of <i>β</i>-Lactam Antibiotics on Surface Modifications of Multidrug-Resistant <i>Escherichia coli</i>: A Multiscale Approach
The Effects of <i>β</i>-Lactam Antibiotics on Surface Modifications of Multidrug-Resistant <i>Escherichia coli</i>: A Multiscale Approach Open
Possible multidrug-resistant (MDR) mechanisms of four resistant strains of Escherichia coli to a model β -lactam, ampicillin, were investigated using contact angle measurements of wettability, crystal violet assays of permeability, biofilm…
View article: Direct-Ink-Writing of Degradable Carboxymethylcellulose
Direct-Ink-Writing of Degradable Carboxymethylcellulose Open
Additive manufacturing with degradable polymers have recently drawn significant attention due to its promising biomedical applications including artificial tissue engineering, surgical, and orthopedic devices etc. This paper experimentally…
View article: Evaluation of β1-integrin expression on chondrogenically differentiating human adipose-derived stem cells using atomic force microscopy
Evaluation of β1-integrin expression on chondrogenically differentiating human adipose-derived stem cells using atomic force microscopy Open
The expression of β1-integrin on human adipose-derived stem cells, differentiating toward a chondrogenic lineage, is hypothesized to decrease when cells are grown under in vivo-like environments due to sufficient extracellular matrix (ECM)…
View article: Expression of N-Cadherins on Chondrogenically Differentiating Human Adipose Derived Stem Cells Using Single-Molecule Force Spectroscopy
Expression of N-Cadherins on Chondrogenically Differentiating Human Adipose Derived Stem Cells Using Single-Molecule Force Spectroscopy Open
N-cadherins are important in the initial steps of mesenchymal stem cell chondrogenic differentiation referred to as pre-cartilage condensation. Because of that, the expression of N-cadherinson the surfaces of human adipose-derived stem cel…