Neil Blumberg
YOU?
Author Swipe
View article: The 2024 international survey of platelet products and practice
The 2024 international survey of platelet products and practice Open
With this addition to the literature on platelet transfusion, considerable heterogeneity in collection, processing, and transfusion can be seen across the globe, through which readers may adopt, and adapt, best practices for their unique l…
View article: Hyperbaric Oxygen (HBO) Effects on Blood Count Recovery and Post Transplant Outcomes Following High-Dose Therapy and Autologous HSPC Transplantation for Multiple Myeloma: Final Analysis of the Multicenter Phase II Randomized Clinical Trial
Hyperbaric Oxygen (HBO) Effects on Blood Count Recovery and Post Transplant Outcomes Following High-Dose Therapy and Autologous HSPC Transplantation for Multiple Myeloma: Final Analysis of the Multicenter Phase II Randomized Clinical Trial Open
Background: In vivo studies showed that hyperbaric oxygen (HBO) promoted the homing of transplanted umbilical cord hematopoietic stem/progenitor cells (HSPC) to the bone marrow by reducing systemic erythropoietin (EPO) levels. In a pilot s…
View article: Red Cell Alloimmunization Rate in Patients with Sickle Cell Disease
Red Cell Alloimmunization Rate in Patients with Sickle Cell Disease Open
Background: Sickle cell disease(SCD) is a single gene disorder resulting in dysfunctional hemoglobin tetramers that polymerize causing vaso-occlusion (VOC), hemolysis, endothelial damage and inflammation leading to pain and end-organ damag…
View article: Patient blood management: Myths and facts about red blood cell transfusions
Patient blood management: Myths and facts about red blood cell transfusions Open
Transfusion medicine resembles all of medicine in that expert opinion predominates because hard data on clinical outcomes from randomized controlled trials and high quality observational data are simply unavailable. Indeed, some of the fir…
View article: National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies Open
Over the last 75 years, the Association for the Advancement of Blood and Biotherapies (AABB) has been advancing blood and biotherapies through professional development, the establishment of standards, and the accreditation of facilities. I…
View article: Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption
Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption Open
ABO immune complexes (ABO-IC) formed by ABO-incompatible antigen-antibody interaction are associated with hemolysis and platelet destruction in patients transfused with ABO-nonidentical blood products. However, the effects of ABO-IC on end…
View article: Reducing the Need for HLA-Matched Platelet Transfusion
Reducing the Need for HLA-Matched Platelet Transfusion Open
Reducing the Need for HLA-Matched Platelet Transfusion Some patients with acute leukemia or myelodysplastic syndromes with thrombocytopenia may become resistant to random donor transfusions of plat...
View article: Faculty Opinions recommendation of Convalescent plasma in the management of moderate COVID-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial).
Faculty Opinions recommendation of Convalescent plasma in the management of moderate COVID-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial). Open
Read the full review for this Faculty Opinions recommended article: Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial).
View article: Impact of RBC Transfusion on Peripheral Capillary Oxygen Saturation and Partial Pressure of Arterial Oxygen
Impact of RBC Transfusion on Peripheral Capillary Oxygen Saturation and Partial Pressure of Arterial Oxygen Open
Objectives RBCs are known to undergo deleterious changes during storage, known as storage lesions, which have been shown to result in decreased oxygen-carrying capacity. However, there is inadequate literature describing the effects of sto…
View article: Faculty Opinions recommendation of ABO-incompatible platelets are associated with increased transfusion reaction rates.
Faculty Opinions recommendation of ABO-incompatible platelets are associated with increased transfusion reaction rates. Open
BACKGROUND: ABO compatibility can affect platelet transfusion safety and efficacy, and ABO-incompatible (ABOi) platelets likely increases the risks of transfusion reactions though the magnitude of this risk is unclear. STUDY DESIGN AND MET…
View article: Faculty Opinions recommendation of Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing non-cardiac surgery or invasive procedures.
Faculty Opinions recommendation of Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing non-cardiac surgery or invasive procedures. Open
Read the full review for this Faculty Opinions recommended article: Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing non-cardiac surgery or invasive procedures.
View article: Total plasma heme concentration increases after red blood cell transfusion and predicts mortality in critically ill medical patients
Total plasma heme concentration increases after red blood cell transfusion and predicts mortality in critically ill medical patients Open
BACKGROUND Relationships between red blood cell (RBC) transfusion, circulating cell‐free heme, and clinical outcomes in critically ill transfusion recipients are incompletely understood. The goal of this study was to determine whether tota…
View article: Masthead and Table of Contents
Masthead and Table of Contents Open
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in
View article: Faculty Opinions recommendation of Is platelet transfusion associated with hospital-acquired infections in critically ill patients?
Faculty Opinions recommendation of Is platelet transfusion associated with hospital-acquired infections in critically ill patients? Open
Background: Platelets are commonly transfused to critically ill patients.Reports suggest an association between platelet transfusion and infection.However, there is no large study to have determined whether platelet transfusion in critical…