Neil Bodagh
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View article: Peri-Atrial Adipose Tissue Inflammation in Atrial Fibrillation
Peri-Atrial Adipose Tissue Inflammation in Atrial Fibrillation Open
Peri-atrial adipose tissue volume was greater in patients with AF. Increased peri-atrial adipose tissue burden and reduced attenuation were spatially but weakly correlated with adverse electrophysiological remodeling in patients with AF.
View article: GenECG: a synthetic image-based ECG dataset to augment artificial intelligence-enhanced algorithm development
GenECG: a synthetic image-based ECG dataset to augment artificial intelligence-enhanced algorithm development Open
Objectives An image-based ECG dataset incorporating visual imperfections common to paper-based ECGs, which are typically scanned or photographed into electronic health records, could facilitate clinically useful artificial intelligence (AI…
View article: Inverse correlation between myocardial wall thickness and conduction velocity in the porcine atrium
Inverse correlation between myocardial wall thickness and conduction velocity in the porcine atrium Open
Introduction Slow conducting regions may be a critical substrate for localized re-entry (1). Variations in myocardial wall thickness may impact atrial conduction velocity, particularly within structurally heterogeneous cardiac tissue (2). …
View article: Characterisation of the bi-atrial electrical substrate in males and females with atrial fibrillation
Characterisation of the bi-atrial electrical substrate in males and females with atrial fibrillation Open
Background The prevalence of atrial fibrillation is greater amongst male patients but there is an increased risk of arrhythmia recurrence following ablation in females. Some studies suggest that females have more advanced left atrial remod…
View article: Enhancing OpenEP: atrial conduction velocity and conduction velocity heterogeneity quantification through EP Workbench
Enhancing OpenEP: atrial conduction velocity and conduction velocity heterogeneity quantification through EP Workbench Open
Background Alterations in atrial conduction velocity have been implicated in the pathogenesis of atrial arrhythmias, with conduction velocity thought to be slower and more heterogeneous in areas promoting atrial fibrillation. However, clin…
View article: Clinical Turing tests with user certainty analysis to create and validate synthetic electrocardiogram images for artificial intelligence-enhanced algorithm development
Clinical Turing tests with user certainty analysis to create and validate synthetic electrocardiogram images for artificial intelligence-enhanced algorithm development Open
Background Artificial intelligence-enhanced electrocardiogram (AI-ECG) algorithms have primarily been created using digitised signal data, owing to a relative absence of publicly available image-based datasets. ECGs are often scanned or ph…
View article: Heterogenous atrial conduction in patients with hypertrophic cardiomyopathy and atrial fibrillation
Heterogenous atrial conduction in patients with hypertrophic cardiomyopathy and atrial fibrillation Open
Background/Introduction Hypertrophic cardiomyopathy (HCM) is characterised by myocardial thickening, fibrosis, and disarray, affecting both ventricles and atria. This pathology extends to atrial tissue, potentially influencing conductivity…
View article: Integrating clinical variables with magnetic resonance imaging and electroanatomic mapping parameters to predict response to first-time and repeat atrial fibrillation ablation procedures
Integrating clinical variables with magnetic resonance imaging and electroanatomic mapping parameters to predict response to first-time and repeat atrial fibrillation ablation procedures Open
Background The heterogeneity in patient response to atrial fibrillation ablation mandates the development of methods to predict clinical outcomes. Several clinical risk scores exist to prognosticate patients post ablation. Magnetic resonan…
View article: High Prevalence of New Clinically Significant Findings in Patients With Embolic Stroke of Unknown Source Evaluated by Cardiac Magnetic Resonance Imaging
High Prevalence of New Clinically Significant Findings in Patients With Embolic Stroke of Unknown Source Evaluated by Cardiac Magnetic Resonance Imaging Open
Background Embolic stroke of unknown source (ESUS) accounts for 1 in 6 ischemic strokes. Current guidelines do not recommend routine cardiac magnetic resonance (CMR) imaging in ESUS, and beyond the identification of cardioembolic sources, …
View article: Cardioversion versus ablation versus ‘pace and ablate’ for persistent atrial fibrillation in older patients
Cardioversion versus ablation versus ‘pace and ablate’ for persistent atrial fibrillation in older patients Open
Our objective was to compare the efficacy of atrial fibrillation (AF) ablation versus permanent pacemaker (PPM) with atrioventricular node ablation (AVNA) versus direct current cardioversion (DCCV) for persistent AF in patients ≥65 years o…
View article: GenECG: A synthetic image-based ECG dataset to augment artificial intelligence-enhanced algorithm development
GenECG: A synthetic image-based ECG dataset to augment artificial intelligence-enhanced algorithm development Open
Background Artificial intelligence-enhanced electrocardiogram (AI-ECG) algorithms have primarily been developed using digitised signal data, due to a relative absence of image-based datasets. An image-based ECG dataset incorporating artefa…
View article: 103 Creation of an image-based electrocardiogram dataset to facilitate real-world artificial intelligence-enhanced electrocardiogram analysis
103 Creation of an image-based electrocardiogram dataset to facilitate real-world artificial intelligence-enhanced electrocardiogram analysis Open
Background Artificial intelligence-enhanced electrocardiogram (AI-ECG) analysis offers the potential to improve care for patients with cardiovascular disease. Most of the algorithms developed to date are limited by their reliance on digita…
View article: Mitral annular electrogram morphology - a balanced signal does not identify the anatomical annulus
Mitral annular electrogram morphology - a balanced signal does not identify the anatomical annulus Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): British Heart Foundation Background Electrogram morphology is used to identify the atrio-ventricular annuli during catheter ablation procedures with a "b…
View article: Feasibility of artificial intelligence-enhanced electrocardiogram (AI-ECG) analysis in the current clinical environment: An online survey
Feasibility of artificial intelligence-enhanced electrocardiogram (AI-ECG) analysis in the current clinical environment: An online survey Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): The study was funded by a University of Edinburgh Wellcome Trust iTPA award. The authors acknowledge the support of the British Heart Foundation Centre f…
View article: Performance of atrial conduction velocity algorithms: a comparative in-silico study
Performance of atrial conduction velocity algorithms: a comparative in-silico study Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): British Heart Foundation Background Atrial conduction velocity is a key determinant of re-entry. Measurement of conduction velocity from electroanatomic …
View article: The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function
The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function Open
There is increasing evidence to suggest that atrial fibrillation is associated with a heightened risk of dementia. The mechanism of interaction is unclear. Atrial fibrillation-induced cerebral infarcts, hypoperfusion, systemic inflammation…
View article: State of the art paper: Cardiac computed tomography of the left atrium in atrial fibrillation
State of the art paper: Cardiac computed tomography of the left atrium in atrial fibrillation Open
The clinical spectrum of atrial fibrillation means that a patient-individualized approach is required to ensure optimal treatment. Cardiac computed tomography can accurately delineate atrial structure and function and could contribute to a…
View article: Evaluation of an Open-Source Pipeline to Create Patient-Specific Left Atrial Models: A Reproducibility Study
Evaluation of an Open-Source Pipeline to Create Patient-Specific Left Atrial Models: A Reproducibility Study Open
We present an open-source software pipeline to create patient-specific left atrial (LA) models with fibre orientations and a fibrosis map, suitable for electrophysiology simulations. The semi-automatic pipeline takes as input a contrast en…
View article: Updates on OpenEP: The Open-Source Platform for Elec-trophysiological Data Analysis
Updates on OpenEP: The Open-Source Platform for Elec-trophysiological Data Analysis Open
OpenEPis an open-source library for electrophysiological data analysis, first released in 2020.This paper provides an update on the features and tools added since initial release.Software development has been performed in Matlab (R2020a/R2…
View article: Synchronous atrioventricular sequential pacing utilizing conventional and leadless pacemakers in an elderly patient: a case report
Synchronous atrioventricular sequential pacing utilizing conventional and leadless pacemakers in an elderly patient: a case report Open
Background Leadless pacemakers present a viable alternative to conventional transvenous devices to mitigate the risk of lead- and/or pocket-related complications. In elderly patients who have encountered ventricular lead failures with tran…
View article: Left Bundle Area Pacing for Tachycardia-Bradycardia Syndrome in a Patient With Dextrocardia
Left Bundle Area Pacing for Tachycardia-Bradycardia Syndrome in a Patient With Dextrocardia Open
We present the case of an 81-year-old woman with a background of situs inversus with dextrocardia who was successfully treated for tachycardia-bradycardia syndrome with left bundle area pacing. This report describes how this approach can c…
View article: Cardiac tamponade from anticoagulant-related spontaneous haemopericardium in a patient with ischaemic cardiomyopathy and heart failure
Cardiac tamponade from anticoagulant-related spontaneous haemopericardium in a patient with ischaemic cardiomyopathy and heart failure Open
We describe the case of an 86-year-old man with a background of severe left ventricular dysfunction and ischaemic cardiomyopathy who, having been optimised for heart failure therapy in hospital, unexpectedly deteriorated again with hypoten…
View article: Hyponatraemia: the importance of obtaining a detailed history and corroborating point-of-care analysis with laboratory testing
Hyponatraemia: the importance of obtaining a detailed history and corroborating point-of-care analysis with laboratory testing Open
We describe a 67-year-old man admitted from a mental health unit with an incidental finding of hyponatraemia on routine blood tests. Laboratory investigations were in keeping with syndrome of inappropriate antidiuretic hormone secretion (S…
View article: β<sub>3</sub>‐Adrenoceptor stimulation of perivascular adipocytes leads to increased fat cell‐derived NO and vascular relaxation in small arteries
β<sub>3</sub>‐Adrenoceptor stimulation of perivascular adipocytes leads to increased fat cell‐derived NO and vascular relaxation in small arteries Open
Background and Purpose In response to noradrenaline, healthy perivascular adipose tissue (PVAT) exerts an anticontractile effect on adjacent small arterial tissue. Organ bath solution transfer experiments have demonstrated the release of P…