Nebu George Thomas
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View article: Oral health disparities among children with special healthcare needs: a comparative cross-sectional study
Oral health disparities among children with special healthcare needs: a comparative cross-sectional study Open
Purpose Children with special healthcare needs (SHCN) often experience poorer oral health due to limitations in self-care, behavioral challenges, medical conditions, and reduced access to specialized dental services. This study aimed to as…
View article: Evaluation of the Impact of Thermocycling on Different Orthodontic Clear Aligner Materials Shear Strength: An In Vitro Study
Evaluation of the Impact of Thermocycling on Different Orthodontic Clear Aligner Materials Shear Strength: An In Vitro Study Open
In orthodontic therapy, the aligner is becoming a preferred esthetic substitute for fixed labial braces all around the world. It is essential to use the best aligner material available to provide consistent pressures for tooth displacement…
View article: In vitro and in vivo biocompatibility of a porcine cholecystic extracellular matrix (CECM) membrane for tissue regeneration
In vitro and in vivo biocompatibility of a porcine cholecystic extracellular matrix (CECM) membrane for tissue regeneration Open
Background Periodontal disease affects 3.5 billion people globally, resulting in annual treatment costs exceeding $54 billion. Guided tissue regeneration (GTR) membranes are essential for periodontal therapy, but commercially available opt…
View article: Bioglass in dentistry: A comprehensive review of current applications and innovative frontiers
Bioglass in dentistry: A comprehensive review of current applications and innovative frontiers Open
Bioglass is a versatile bioactive material with the potential to transform clinical dental practice. Advancements in AI have enabled the customized treatment strategies, through predictive modeling, enhanced regenerative outcomes, and opti…
View article: Salivary Cystatin C as a Potential Biomarker in Stage III/IV Periodontitis: A Comparative Study
Salivary Cystatin C as a Potential Biomarker in Stage III/IV Periodontitis: A Comparative Study Open
Aim: Periodontitis is a chronic, multifactorial inflammatory disease characterized by progressive destruction of the supporting periodontal tissues. Early identification of disease activity and severity remains a clinical challenge. Saliva…
View article: Nano carbon dot-collagen peptide – Hydroxyapatite composite coating for bone tissue regeneration
Nano carbon dot-collagen peptide – Hydroxyapatite composite coating for bone tissue regeneration Open
Biological derivatives are the preferred coating materials for enhancing osseointegration in bone implants. The present study aimed to develop a nanocomposite from fish waste, comprising of carbon dots (CD), collagen peptides (CP), and nat…
View article: Systematic review and meta-analysis on marginal bone loss of dental implants placed in augmented or pristine bone sites: Findings from clinical long-term studies
Systematic review and meta-analysis on marginal bone loss of dental implants placed in augmented or pristine bone sites: Findings from clinical long-term studies Open
Dental implants in augmented bone sites show greater MBL after five years compared to pristine bone sites. Augmentation may increase early bone remodeling. Clinicians should consider augmentation-related remodeling dynamics and patient-spe…
View article: Evaluation of the Anticandidal Effect of Medicinal Plant Extracts to Drug Resistant Candida Albicans Isolates from Type Two Diabetic patients with Stage Three Periodontitis
Evaluation of the Anticandidal Effect of Medicinal Plant Extracts to Drug Resistant Candida Albicans Isolates from Type Two Diabetic patients with Stage Three Periodontitis Open
A BSTRACT Objectives: To assess the anticandidal efficacy of nine medicinal plants to drug resistant Candida albicans isolates from diabetic patients with chronic periodontitis. A comparison was done with chlorhexidine gluconate. Methods: …
View article: Fluoride Concentrations in Different Brands of Toothpaste Marketed in Saudi Arabia
Fluoride Concentrations in Different Brands of Toothpaste Marketed in Saudi Arabia Open
Objectives This study aimed to evaluate the concentrations of total fluoride (TF), total soluble fluoride (TSF) and ionic fluoride (IF) in various toothpaste brands marketed in Saudi Arabia and compare them with the labelled values. Method…
View article: Oral health status and dental treatment needs in children with autism spectrum disorder
Oral health status and dental treatment needs in children with autism spectrum disorder Open
Compared to non-ASD peers, children with ASD have lower dental caries prevalence and less need for restorations, yet poorer plaque control. They also demonstrate more frequent oral self-injuries. ASD status appears related to toothbrushing…
View article: Domestic Chicken Eggshell-Derived Bone Substitute: Synthesis, Characterization and In Vitro Cell Viability
Domestic Chicken Eggshell-Derived Bone Substitute: Synthesis, Characterization and In Vitro Cell Viability Open
A BSTRACT Background: Hydroxyapatite (HA) is a material with excellent bioactivity and chemical similarity to bone. It can be extracted from natural sources or fabricated synthetic sources. Objective: To synthesize HA from domestic chicken…
View article: Salivary biomarkers – Emerging era in periodontics
Salivary biomarkers – Emerging era in periodontics Open
Periodontitis is a chronic inflammatory noncommunicable disease that affects all parts of the periodontium and causes irreversible damage. A biological sign of either pathogenic or normal processes is called a biomarker. Finding biomarkers…
View article: Association between metabolic syndrome and salivary <scp>MMP</scp> ‐8, myeloperoxidase in periodontitis
Association between metabolic syndrome and salivary <span>MMP</span> ‐8, myeloperoxidase in periodontitis Open
Objective This study investigated the effect of metabolic syndrome (MetS) on periodontal clinical parameters and salivary biomarkers' matrix metalloproteinase‐8 (MMP‐8) and myeloperoxidase (MPO) in patients with periodontitis. Methods A to…
View article: Toxicity of Natural Hydroxyapatite
Toxicity of Natural Hydroxyapatite Open
Hydroxyapatite (HA) has been extensively researched in bone regeneration procedures for its close similarity with natural bone in composition and also due to its osteoconductive and bone healing properties. Natural hydroxyapatite (NHA) is …
View article: Fabrication Techniques for Scaffolds Applied in Regenerative Medicine
Fabrication Techniques for Scaffolds Applied in Regenerative Medicine Open
Tissue engineering strategies in regenerative medicine combine cells, scaffolds, and growth factors to regenerate and reconstruct pathologically damaged tissues such as periodontium, bone, nerves, cartilage skin, heart valves, and various …
View article: Physiochemical and Biomedical Properties of Hydrogels: From Fundamentals to Applications
Physiochemical and Biomedical Properties of Hydrogels: From Fundamentals to Applications Open
Translational research is utilizing the hydrophilic characteristic of polymer structures, which possess the physical or chemical cross-linking capability. This attribute has been applied in pharmaceutical research to develop hydrogels, whi…
View article: Knowledge of the monkeypox 2022 outbreak among dental hygienists and students in Saudi Arabia: A cross‐sectional study
Knowledge of the monkeypox 2022 outbreak among dental hygienists and students in Saudi Arabia: A cross‐sectional study Open
Objective This study aimed to assess the knowledge of monkeypox infection among dental hygiene professionals and students in Saudi Arabia. Methods A cross‐sectional study was conducted among a convenience sample of dental hygiene professio…
View article: An application of decellularized membrane as guided tissue regeneration
An application of decellularized membrane as guided tissue regeneration Open
Decellularized Extracellular Matrix (DECM) has been established as a biomaterial that retains the natural properties of a tissue, promotes cell proliferation and cell differentiation. Periodontal regeneration requires the neovascularizatio…
View article: Biological modifiers in bone graft for periodontal regeneration
Biological modifiers in bone graft for periodontal regeneration Open
Periodontal diseases such as gingivitis and periodontitis leads to degradation of periodontal tissues, causing tooth movement, and eventually tooth loss. Regenerative periodontal therapies aim to promote the healing and regeneration of the…
View article: Toxicity Evaluation and Biocompatibility of Nanostructured Biomaterials
Toxicity Evaluation and Biocompatibility of Nanostructured Biomaterials Open
Biomaterials have occupied a prominent place in regenerative procedures to restore human health. Moreover, there is a greater need in understanding, analyzing and establishing their toxicity profile. These, when made into nano-sized constr…
View article: Effectiveness of Platelet-Rich Fibrin with Decalcified Freeze-Dried Bone Allograft Compared to Decalcified Freeze-Dried Bone Allograft Alone in Mandibular Grade-II Furcation Defects: A Quasi-Experimental Study
Effectiveness of Platelet-Rich Fibrin with Decalcified Freeze-Dried Bone Allograft Compared to Decalcified Freeze-Dried Bone Allograft Alone in Mandibular Grade-II Furcation Defects: A Quasi-Experimental Study Open
Objective: To assess the effectiveness of platelet-rich fibrin (PRF) with decalcified freeze-dried bone allograft (DFDBA) compared to DFDBA alone in mandibular grade-II furcation defects. Material and Methods: A quasi-experimental study wa…
View article: The Design of 3D-Printed Polylactic Acid–Bioglass Composite Scaffold: A Potential Implant Material for Bone Tissue Engineering
The Design of 3D-Printed Polylactic Acid–Bioglass Composite Scaffold: A Potential Implant Material for Bone Tissue Engineering Open
Bio-based and patient-specific three-dimensional (3D) scaffolds can present next generation strategies for bone tissue engineering (BTE) to treat critical bone size defects. In the present study, a composite filament of poly lactic acid (P…
View article: Perception of COVID-19 Booster Dose Vaccine among Healthcare Workers in India and Saudi Arabia
Perception of COVID-19 Booster Dose Vaccine among Healthcare Workers in India and Saudi Arabia Open
Background: COVID-19 vaccines were made available to the public by the end of 2020. However, little is known about COVID-19 booster dose (CBD) vaccine perception among healthcare workers (HCW) worldwide. The present study aims to assess th…
View article: Cone-Beam Computed Tomography-Assisted Evaluation of the Bone Regenerative Potential of Modulated Sol–Gel-Synthesized 45S5 Bioglass Intended for Alveolar Bone Regeneration
Cone-Beam Computed Tomography-Assisted Evaluation of the Bone Regenerative Potential of Modulated Sol–Gel-Synthesized 45S5 Bioglass Intended for Alveolar Bone Regeneration Open
Objectives: The objective of the study was to evaluate the in vitro cell compatibility and in vivo regenerative potential of 45S5 Bioglass (45S5-BG)-based bone graft implanted in critical-size defects (CSD) created at rat calvaria using co…
View article: Applications of xenografts in periodontal regeneration
Applications of xenografts in periodontal regeneration Open
Periodontitis is a disease with a high prevalence among adults. If not treated, it can lead to loss of teeth. New attachment with periodontal regeneration is the ideal outcome of periodontal therapy since it results in reconstruction of th…