Explanipedia

Longitudinal Performance Assessment of an AI-Based Auto-Segmentation Tool Using Statistical Process Control Open

D. Hobbis, Zhen Chen, Michael R. Waters, Jon B. Hansen, Nels Knutson , et al. · 2025

Electronic Chart Recording for Gamma Knife Stereotactic Radiosurgery Open

S Ferguson, G. Kamal, Nels Knutson, Timothy J. Mitchell, Sreekrishna Murty Goddu , et al. · 2025

Feasibility of surface‐guidance combined with CBCT for intra‐fractional breath‐hold motion management during Ethos RT Open

Taeho Kim, Eric Laugeman, Kendall Kiser, Joshua P. Schiff, Shanti Marasini , et al. · 2024

Purpose High‐quality CBCT and AI‐enhanced adaptive planning techniques allow CBCT‐guided stereotactic adaptive radiotherapy (CT‐STAR) to account for inter‐fractional anatomic changes. Studies of intra‐fractional respiratory motion manageme…

In silico trial of simulation-free hippocampal-avoidance whole brain adaptive radiotherapy Open

Alex Price, Kylie H. Kang, Francisco J. Reynoso, Eric Laugeman, Christopher Abraham , et al. · 2023

Simulation-free HA-WBRT, with commercially available systems, was clinically feasible via plan-quality metrics and timing, in silico.

PO-05-104 FEASIBILITY STUDY OF SINGLE DAY SIMULATION- FREE CARDIAC RADIOABLATION WORKFLOW WITH A PORCINE MODEL Open

Nels Knutson, Thomas R. Mazur, Tianyu Zhao, Michael T. Prusator, Geoffrey D. Hugo , et al. · 2023

Clinical application of a template‐guided automated planning routine Open

Matthew C. Schmidt, Christopher Abraham, Jiayi Huang, Clifford G. Robinson, Geoffrey D. Hugo , et al. · 2022

Purpose Determine the dosimetric quality and the planning time reduction when utilizing a template‐based automated planning application. Methods A software application integrated through the treatment planning system application programing…

Technical note: Institutional solution of clinical cine MRI for tumor motion evaluation in radiotherapy Open

Taeho Kim, Yu Wu, Zhen Ji, H. Michael Gach, Nels Knutson , et al. · 2022

Purpose Since 4D‐MRI is inadequate to capture dynamic respiratory variations, real‐time cinematographic (cine) MRI is actively used in MR‐guided radiotherapy (MRgRT) for tumor motion evaluation, delineation, and tracking. However, most rad…

Commissioning a secondary dose calculation software for a 0.35 T MR‐linac Open

Alex Price, Nels Knutson, Taeho Kim, Olga L. Green · 2022

Secondary external dose calculations for a 0.35 T magnetic resonance image‐guided radiation therapy (MRgRT) are needed within the radiation oncology community to follow safety standards set forth within the field. We evaluate the commercia…

Visually guided respiratory motion management for Ethos adaptive radiotherapy Open

Taeho Kim, Zhen Ji, Benjamin Lewis, Eric Laugeman, Alex Price , et al. · 2021

Purpose Ethos adaptive radiotherapy (ART) is emerging with AI‐enhanced adaptive planning and high‐quality cone‐beam computed tomography (CBCT). Although a respiratory motion management solution is critical for reducing motion artifacts on …

Clinical Workflow for Planning and Treating Palliative Patients on Diagnostic Images Open

Tianyu Zhao, Hyoung‐Il Kim, Lauren E. Henke, Clifford G. Robinson, Baozhou Sun , et al. · 2021

Radiation Oncology Alternative Payment Model (RO-APM) Monte Carlo Simulations to Predict Financial Impact and Viability for Common Practice Types Open

Alex Price, James Kavanaugh, Nels Knutson, Geoffrey D. Hugo, Cameron Spencer · 2021

Application programming interface guided QA plan generation and analysis automation Open

Matthew C. Schmidt, Caleb A. Raman, Yu Wu, Mahmoud Yaqoub, Yao Hao , et al. · 2021

Purpose Linear accelerator quality assurance (QA) in radiation therapy is a time consuming but fundamental part of ensuring the performance characteristics of radiation delivering machines. The goal of this work is to develop an automated …

Radiation oncology physics coverage during the COVID‐19 pandemic: Successes and lessons learned Open

Nels Knutson, James Kavanaugh, H Harold Li, Jacqueline E. Zoberi, Tianyu Zhao , et al. · 2021

The Coronavirus 2019 (COVID-19) pandemic has severely impacted healthcare systems by putting a massive strain on emergency, intensive care, internal medicine departments, and caregivers. Outpatient care, including radiation oncology, has a…

Spatially fractionated stereotactic body radiation therapy (Lattice) for large tumors Open

Sai Duriseti, James Kavanaugh, Sreekrishna Goddu, Alex Price, Nels Knutson , et al. · 2021

Filmless quality assurance of a Leksell Gamma Knife® Icon™ Open

B. Maraghechi, Taeho Kim, Timothy J. Mitchell, S Goddu, Joe Dise , et al. · 2020

Purpose The annual quality assurance (QA) of Leksell Gamma Knife ® (LGK) systems are typically performed using films. Film is a good candidate for small field dosimetry due to its high spatial resolution and availability. However, there ar…

Portal dosimetry scripting application programming interface (PDSAPI) for Winston‐Lutz test employing ceramic balls Open

Yao Hao, Matthew C. Schmidt, Yu Wu, Nels Knutson · 2020

Purpose Stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments require a high degree of accuracy. Mechanical, imaging, and radiation isocenter coincidence is especially important. As a common method, the …

Automated and robust beam data validation of a preconfigured ring gantry linear accelerator using a 1D tank with synchronized beam delivery and couch motions Open

Nels Knutson, Matthew C. Schmidt, Francisco J. Reynoso, Yao Hao, Thomas R. Mazur , et al. · 2020

Purpose To develop an efficient and automated methodology for beam data validation for a preconfigured ring gantry linear accelerator using scripting and a one‐dimensional (1D) tank with automated couch motions. Materials and methods Using…

Implementing a Novel Remote Physician Treatment Coverage Practice for Adaptive Radiation Therapy During the Coronavirus Pandemic Open

Alex Price, Hyun Kim, Lauren E. Henke, Nels Knutson, Matthew B. Spraker , et al. · 2020

Implementation of a Novel Remote Physician Stereotactic Body Radiation Therapy Coverage Process during the Coronavirus Pandemic Open

Alex Price, Lauren E. Henke, B. Maraghechi, Taeho Kim, Matthew B. Spraker , et al. · 2020

Implementation of a Novel Remote Physician SBRT Coverage Process during the Coronavirus Pandemic Open

Alex Price, Lauren E. Henke, B. Maraghechi, Taeho Kim, Matthew B. Spraker , et al. · 2020

INTRODUCTION During the COVID-19 pandemic, alternative methods of care are needed to reduce the relative risk of transmission in departments. Also needed is the ability to provide vital radiation oncological care if radiation oncologists (…

Spatially fractionated stereotactic body radiotherapy (Lattice SBRT) for large tumors Open

Sai Duriseti, James Kavanaugh, Sreekrishna Goddu, Alex Price, Nels Knutson , et al. · 2020

Stereotactic body radiotherapy (SBRT) has demonstrated clinical benefit for patients with metastatic and/or unresectable cancer. Technical considerations of treatment delivery and sensitive organs at risk (OARs) limit the use of SBRT in la…

Noninvasive Cardiac Radioablation at Washington University: Past, Present and Future Directions for the Treatment of Ventricular Tachycardia Open

Pamela Samson, Geoff Hugo, Kaitlin Moore, Nels Knutson, Philip Cuculich , et al. · 2020

Intracranial Stereotactic Radiation Therapy With a Jawless Ring Gantry Linear Accelerator Equipped With New Dual Layer Multileaf Collimator Open

Nels Knutson, William R. Kennedy, Francisco J. Reynoso, Jiayuan Peng, Lauren E. Henke , et al. · 2020

Evaluation of a new secondary dose calculation software for Gamma Knife radiosurgery Open

Michael T. Prusator, Tianyu Zhao, James Kavanaugh, Lakshmi Santanam, Joe Dise , et al. · 2020

Current available secondary dose calculation software for Gamma Knife radiosurgery falls short in situations where the target is shallow in depth or when the patient is positioned with a gamma angle other than 90°. In this work, we evaluat…

Response by Robinson et al to Letter Regarding Article, “Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia” Open

Clifford G. Robinson, Nels Knutson, Pamela Samson, Phillip S. Cuculich · 2019

Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery Open

Nels Knutson, Brad J. Hawkins, Douglas Bollinger, S Goddu, James Kavanaugh , et al. · 2019

Purpose Characterize the intra‐fraction motion management ( IFMM ) system found on the Gamma Knife Icon ( GKI ), including spatial accuracy, latency, temporal performance, and overall effect on delivered dose. Methods A phantom was constru…

Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia Open

Clifford G. Robinson, Pamela Samson, Kaitlin Moore, Geoffrey D. Hugo, Nels Knutson , et al. · 2019

Background: Case studies have suggested the efficacy of catheter-free, electrophysiology-guided noninvasive cardiac radioablation for ventricular tachycardia (VT) using stereotactic body radiation therapy, although prospective data are lac…

Feasibility of Noninvasive Cardiac Ablation Utilizing Intensity Modulated Proton Therapy to Treat Ventricular Tachycardia Open

S Goddu, Jessica Hilliard, Nels Knutson, Tianyu Zhao, Geoffrey D. Hugo , et al. · 2018

Equivalency of beam scan data collection using a 1D tank and automated couch movements to traditional 3D tank measurements Open

Nels Knutson, Matthew C. Schmidt, Matthew D. Belley, Ngọc Bích Nguỹên, Michael Price , et al. · 2018

This work shows the feasibility of collecting linear accelerator beam data using just a 1‐D water tank and automated couch movements with the goal to maximize the cost effectiveness in resource‐limited clinical settings. Two commissioning …

AAPM Spring Clinical Meeting – Abstracts Open

Stephen Gardner, Siming Lu, C Liu, Ning Wen, Indrin J. Chetty , et al. · 2017

Purpose: To use end-to-end dosimetric measurements with Gafchromic film to evaluate the effects of focal spot size parameter for Acuros dose calculation of small-field SRS lesions.Methods: A total of 20 VMAT plans (10 with Millennium-120 M…

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