Nelson Alphonso
YOU?
Author Swipe
View article: Population pharmacokinetics of cefazolin administered as prophylaxis in paediatric patients undergoing cardiac surgery
Population pharmacokinetics of cefazolin administered as prophylaxis in paediatric patients undergoing cardiac surgery Open
Postoperative cefazolin concentrations in paediatric patients undergoing cardiopulmonary bypass are often inadequate to maintain optimal antimicrobial prophylaxis. More frequent postoperative dosing or the use of extended and continuous in…
View article: Outcomes of the Fontan operation in patients with Ebstein anomaly: An Australia and New Zealand Fontan registry study
Outcomes of the Fontan operation in patients with Ebstein anomaly: An Australia and New Zealand Fontan registry study Open
Patients with EA have worse long-term outcomes after the Fontan operation compared with other patients with left ventricular dominance. Patients with a prior Starnes procedure appear to have good post-Fontan outcomes, although bias may occ…
View article: Neurodevelopmental Outcomes After Nitric Oxide During Cardiopulmonary Bypass for Open Heart Surgery
Neurodevelopmental Outcomes After Nitric Oxide During Cardiopulmonary Bypass for Open Heart Surgery Open
Importance Children with congenital heart defects who undergo cardiopulmonary bypass (CPB) surgery are at risk for delayed or impaired neurodevelopmental outcomes. Nitric oxide (NO) added to the CPB oxygenator may reduce systemic inflammat…
View article: Viability of Extracorporeal Membrane Oxygenation Circuits during Arterio-venous Shunting: An Observational Study of ECMO Circuits
Viability of Extracorporeal Membrane Oxygenation Circuits during Arterio-venous Shunting: An Observational Study of ECMO Circuits Open
Introduction Trial off veno-arterial extracorporeal membrane oxygenation is often performed by diversion of circuit flow through an arterio-venous shunt. Separation from the patient presents an augmented risk for microbiological growth and…
View article: Hyperlactataemia Following Crystalloid Cardiopulmonary Bypass Priming in Paediatric Cardiac Surgery—Benign or Malignant? A Retrospective Study
Hyperlactataemia Following Crystalloid Cardiopulmonary Bypass Priming in Paediatric Cardiac Surgery—Benign or Malignant? A Retrospective Study Open
Background: Various mechanisms leading to early hyperlactataemia post-cardiac surgery have been postulated. Specifically, in the paediatric population, benign early hyperlactataemia may be associated with crystalloid priming in the cardiop…
View article: CardioCel® for repair of congenital heart defects: nationwide results of over 1000 implants
CardioCel® for repair of congenital heart defects: nationwide results of over 1000 implants Open
OBJECTIVES To assess the mid-term performance of CardioCel for the repair of congenital heart defects. METHODS Data were retrospectively collected from databases and hospital records in 3 congenital cardiac surgery centres in Australia. Ka…
View article: Utility of routine chest radiographs after chest drain removal in paediatric cardiac surgical patients—a retrospective analysis of 1076 patients
Utility of routine chest radiographs after chest drain removal in paediatric cardiac surgical patients—a retrospective analysis of 1076 patients Open
OBJECTIVES Chest drains are routinely placed in children following cardiac surgery. The purpose of this study was to determine the incidence of a clinically relevant pneumothorax and/or pleural effusion after drain removal and to ascertain…
View article: Performance of CardioCel in Cardiac Surgery: A Systematic Review
Performance of CardioCel in Cardiac Surgery: A Systematic Review Open
A systematic review was performed for evaluation of the performance of CardioCel ® in cardiac surgery. The review included all studies published from January 2013 to December 2020. We conclude that CardioCel is a strong, flexible tissue su…
View article: Clinical stakeholder preferences for paediatric cardiac surgery outcome reporting in Australia and New Zealand
Clinical stakeholder preferences for paediatric cardiac surgery outcome reporting in Australia and New Zealand Open
Background: Outcome reporting is an essential element of quality assurance. Evaluation of the information needs of stakeholders of outcome reporting is limited. This study aimed to examine stakeholder preferences for the content, format, a…
View article: Feeding Neonates and Infants Prior to Surgery for Congenital Heart Defects: Systematic Review and Meta-Analysis
Feeding Neonates and Infants Prior to Surgery for Congenital Heart Defects: Systematic Review and Meta-Analysis Open
Background: Necrotising enterocolitis (NEC) is a significant cause of mortality and morbidity in neonates requiring cardiac surgery. Feeding practices vary significantly across institutions and remain controversial. We conducted a systemat…
View article: The Australia and New Zealand Congenital Outcomes Registry for Surgery (<scp>ANZCORS</scp>): methodology and preliminary results
The Australia and New Zealand Congenital Outcomes Registry for Surgery (<span>ANZCORS</span>): methodology and preliminary results Open
Background Analysis of multi‐institutional data and benchmarking is an accepted accreditation standard in cardiac surgery. Such a database does not exist for congenital cardiac surgery in Australia and New Zealand (ANZ). To fill this gap, …
View article: Effect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery
Effect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery Open
anzctr.org.au Identifier: ACTRN12617000821392.
View article: A single-centre, retrospective study of mid-term outcomes of aortic arch repair using a standardized resection and patch augmentation technique
A single-centre, retrospective study of mid-term outcomes of aortic arch repair using a standardized resection and patch augmentation technique Open
OBJECTIVES The aim of this study was to evaluate the mid-term outcomes after the repair of aortic arch using a standard patch augmentation technique. METHODS The study included all patients who underwent repair of a hypoplastic/interrupted…
View article: Impact of Fontan Fenestration on Long‐Term Outcomes: A Propensity Score–Matched Analysis
Impact of Fontan Fenestration on Long‐Term Outcomes: A Propensity Score–Matched Analysis Open
Background The long‐term impact of fenestration at the time of Fontan operation remains unclear. We aimed to review the early and long‐term impact of Fontan fenestration in the Australia and New Zealand cohort. Methods and Results We revie…
View article: Diagnostic Accuracy of Infection Markers to Diagnose Infections in Neonates and Children Receiving Extracorporeal Membrane Oxygenation
Diagnostic Accuracy of Infection Markers to Diagnose Infections in Neonates and Children Receiving Extracorporeal Membrane Oxygenation Open
Background Infections represent one of the most common complications in patients managed on Extracorporeal Membrane Oxygenation (ECMO) and are associated with poorer outcomes. Clinical signs of infection in patients on ECMO are non-specifi…
View article: A case report of mass and pressure: the utility of contrast echocardiography
A case report of mass and pressure: the utility of contrast echocardiography Open
Background Diagnostic dilemmas in an unwell neonate can require the use of enhanced imaging modalities, especially in post-operative cardiac disease. Case summary A neonate presented a diagnostic challenge following the repair of complex t…
View article: Fontan operation at less than 3 years of age is not a risk factor for long-term failure
Fontan operation at less than 3 years of age is not a risk factor for long-term failure Open
OBJECTIVES The age at which the Fontan operation is performed varies globally. Over the last decade, the median age of patients having the Fontan in Australia and New Zealand has been 4.6 years, including 6% of patients younger than 3 year…
View article: Predictors of reoperation and mortality after complete atrioventricular septal defect repair
Predictors of reoperation and mortality after complete atrioventricular septal defect repair Open
OBJECTIVES Previous studies investigating risk factors associated with reoperation or mortality after repair of complete atrioventricular septal defect (CAVSD) often have not included sizeable cohorts undergoing modified single-patch repai…
View article: Queensland Paediatric Cardiac Service: Lessons from evolution to a unified service in a tertiary children's hospital
Queensland Paediatric Cardiac Service: Lessons from evolution to a unified service in a tertiary children's hospital Open
We describe a complex change process for the paediatric cardiac service in Queensland that involved transitioning the service out of an essentially adult hospital into one of two children's hospitals in Brisbane. This initial step was comp…
View article: Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: The European Association for Cardio-Thoracic Surgery (EACTS) and the Association for European Paediatric and Congenital Cardiology (AEPC) Hypoplastic Left Heart Syndrome Guidelines Task Force
Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: The European Association for Cardio-Thoracic Surgery (EACTS) and the Association for European Paediatric and Congenital Cardiology (AEPC) Hypoplastic Left Heart Syndrome Guidelines Task Force Open
The IPCCC is a standardized international system of paediatric and congenital cardiac nomenclature that should be used in all registries, databases and research studies in the domain of paediatric and congenital cardiac care, including tho…