Nerses Bebek
YOU?
Author Swipe
View article: A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of <scp>BPAN</scp>: Insights From a New Case Series
A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of <span>BPAN</span>: Insights From a New Case Series Open
Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 ge…
View article: Post-traumatic Epilepsies: Prophylactic Antiseizure Medications Are Futile
Post-traumatic Epilepsies: Prophylactic Antiseizure Medications Are Futile Open
View article: Uncommon Presentation of Subacute Sclerosing Panencephalitis: Two Cases of Rapidly Progressive Parkinsonism
Uncommon Presentation of Subacute Sclerosing Panencephalitis: Two Cases of Rapidly Progressive Parkinsonism Open
View article: Examination of the Relationship between Psychosomatic Diagnosis and Interpersonal Relationships in Patients with Functional Neurological Symptom Disorder
Examination of the Relationship between Psychosomatic Diagnosis and Interpersonal Relationships in Patients with Functional Neurological Symptom Disorder Open
View article: XhetRel: A Pipeline for X Heterozygosity and Relatedness Analysis in Sequencing Data
XhetRel: A Pipeline for X Heterozygosity and Relatedness Analysis in Sequencing Data Open
Motivation Checking sample sex is one of the preliminary controls performed in genetic studies. Comparing multiple individuals and families in terms of sex and relatedness allows us to eliminate systematic errors in downstream analyses. Wh…
View article: A conserved role for ALG10/ALG10B and the<i>N</i>-glycosylation pathway in the sleep-epilepsy axis
A conserved role for ALG10/ALG10B and the<i>N</i>-glycosylation pathway in the sleep-epilepsy axis Open
Congenital disorders of glycosylation (CDG) comprise a class of inborn errors of metabolism resulting from pathogenic variants in genes coding for enzymes involved in the asparagine-linked glycosylation of proteins. Unexpectedly to date, n…
View article: Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes
Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes Open
View article: Seeing Clowns with a Ring 20 Chromosome
Seeing Clowns with a Ring 20 Chromosome Open
Ring chromosome 20 syndrome is a rare genetic disorder characterized by non-convulsive status epilepticus (NCSE) attacks, leading to prolonged confusional states of varying intensity. It is often accompanied by electroencephalography (EEG)…
View article: Epilepsy Spectrum Associated with <i>PRRT2</i> Variants: Case Presentations
Epilepsy Spectrum Associated with <i>PRRT2</i> Variants: Case Presentations Open
Variations in the PRRT2 gene have been shown to cause a variety of diseases, including benign familial infantile epilepsy (BFIE) and paroxysmal kinesigenic dyskinesia (PKD). Next-generation sequencing techniques have allowed the broadening…
View article: Effectiveness and Safety of Epilepsy Surgery for Pediatric Patients with Intractable Epilepsy: A Clinical Retrospective Study from a Single-Center Experience
Effectiveness and Safety of Epilepsy Surgery for Pediatric Patients with Intractable Epilepsy: A Clinical Retrospective Study from a Single-Center Experience Open
Introduction: Pediatric epilepsy surgery is an effective treatment modality for patients with drug-resistant epilepsy (DRE). Early pediatric surgery yields favorable results for DRE in terms of seizure control and neurophysio…
View article: GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture
GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture Open
View article: Peripheral Blood Regulatory B and T Cells are Decreased in Patients with Focal Epilepsy
Peripheral Blood Regulatory B and T Cells are Decreased in Patients with Focal Epilepsy Open
View article: COVID-19 pandemic in Istanbul: Seizure frequency and psychosocial outcomes in patients with epilepsy
COVID-19 pandemic in Istanbul: Seizure frequency and psychosocial outcomes in patients with epilepsy Open
Objective: The aim of this study was to examine seizure frequency and psychosocial outcomes in patients with epilepsy (PwE) during the COVID-19 pandemic. Methods: This cross-sectional case- control study included 319 adult PwE and 327 heal…
View article: The effect of fear of COVID-19 on quality of life in patients with epilepsy
The effect of fear of COVID-19 on quality of life in patients with epilepsy Open
Objective: In the COVID-19 pandemic period, the effect of COVID-19 fear on quality of life was uncertain. This present study examined the effect of fear of COVID-19 on quality of life in patients with epilepsy through anxiety and depressio…
View article: Reevaluation of the Electroencephalogram Recordings of Patients with Nonconvulsive Status Epilepticus by Using Salzburg Consensus Criteria
Reevaluation of the Electroencephalogram Recordings of Patients with Nonconvulsive Status Epilepticus by Using Salzburg Consensus Criteria Open
Objective: Nonconvulsive status epilepticus (NCSE) is a challenge to diagnose in some cases, and recently, Salzburg consensus criteria for NCSE (SCC-NCSE) were developed to contribute to clinical practice. We aimed to investigate their val…
View article: Clinical and Genetic Features in Patients With Reflex Bathing Epilepsy
Clinical and Genetic Features in Patients With Reflex Bathing Epilepsy Open
Objective: To describe the clinical and genetic findings in a cohort of subjects with bathing epilepsy, a rare form of reflex epilepsy. Methods: We investigated by Sanger and targeted re-sequencing the SYN1 gene in 12 individuals from 10 d…
View article: POSITRON EMISSION TOMOGRAPHY IN PATIENTS WITH DRUG RESISTANT TEMPORAL LOBE EPILEPSY WITH DIFFERENT ICTAL PROPAGATION PATTERNS IN SCALP EEG
POSITRON EMISSION TOMOGRAPHY IN PATIENTS WITH DRUG RESISTANT TEMPORAL LOBE EPILEPSY WITH DIFFERENT ICTAL PROPAGATION PATTERNS IN SCALP EEG Open
Objective: In presurgical evaluation, positron emission tomography with fluorodeoxyglucose-F18 (FDG-PET) is an important tool in identifying epileptogenic area. The aim of this study was to evaluate glucose metabolism in FDG-PET in patient…
View article: Elevated sTREM2 and NFL levels in patients with sepsis associated encephalopathy
Elevated sTREM2 and NFL levels in patients with sepsis associated encephalopathy Open
sTREM2 and NFL levels may serve as a prognostic biomarker for cognitive decline in SAE. These results lend further support for the involvement of glial activation and neuroaxonal degeneration in the physiopathology of SAE.
View article: Depression is a major determinant of sleep abnormalities in patients with epilepsy
Depression is a major determinant of sleep abnormalities in patients with epilepsy Open
Introduction: We aimed to identify sleep disorders in patients with epilepsy and compare this group with a healthy population. We also analyzed the features of sleep disorders in patients with epilepsy to demonstrate the effect of seizures…
View article: Progressive Myoclonus Epilepsy Caused by a Homozygous Splicing Variant of <scp><i>SLC7A6OS</i></scp>
Progressive Myoclonus Epilepsy Caused by a Homozygous Splicing Variant of <span><i>SLC7A6OS</i></span> Open
Exome sequencing was performed in 2 unrelated families with progressive myoclonus epilepsy. Affected individuals from both families shared a rare, homozygous c.191A > G variant affecting a splice site in SLC7A6OS . Analysis of cDNA from ly…
View article: Functional connectivity analysis of patients with temporal lobe epilepsy displaying different ictal propagation patterns<sup>*</sup>
Functional connectivity analysis of patients with temporal lobe epilepsy displaying different ictal propagation patterns<sup>*</sup> Open
Aims The pathophysiology of switch‐of lateralization and bilateral temporal asynchrony, which are scalp EEG ictal propagation patterns (iPP) in temporal lobe epilepsy (TLE), is poorly understood. We aimed to analyse functional connectivity…
View article: Corrigendum to “Relationships between knowledge, attitudes, stigma, anxiety and depression, and quality of life in epilepsy: A structural equation modeling” [Epilepsy Behav 85 (2018) 212–217]
Corrigendum to “Relationships between knowledge, attitudes, stigma, anxiety and depression, and quality of life in epilepsy: A structural equation modeling” [Epilepsy Behav 85 (2018) 212–217] Open
View article: SCREENING SLC2A1 GENE FOR SEQUENCE AND COPY NUMBER VARIATIONS ASSOCİATED WITH GLUT-1 DEFICIENCY SYNDROME
SCREENING SLC2A1 GENE FOR SEQUENCE AND COPY NUMBER VARIATIONS ASSOCİATED WITH GLUT-1 DEFICIENCY SYNDROME Open
Objective: Glucose transporter-1 deficiency syndrome (GLUT1- DS) is defined as a metabolic encephalopathy that is associated with heterozygous and usually de novo pathogenic variations in the SLC2A1 (solute carrier family2 member1) gene. M…
View article: GLUT-1 EKSİKLİĞİ SENDROMU İLE İLİŞKİLİ SLC2A1 GENİNDE YER ALAN DİZİ VE KOPYA SAYISI VARYASYONLARININ İNCELENMESİ
GLUT-1 EKSİKLİĞİ SENDROMU İLE İLİŞKİLİ SLC2A1 GENİNDE YER ALAN DİZİ VE KOPYA SAYISI VARYASYONLARININ İNCELENMESİ Open
Amaç: GLUT1 eksikliği sendromu (GLUT-1ES) bebeklik çağında başlayan metabolic bir ensefalopati olarak tanımlanmıştır. Kolaylaştırılmış glikoz taşıyıcısı olan GLUT1’i kodlayan SLC2A1 genindeki de novo patojenik varyasyonlardan kaynaklanır. …
View article: The COVID-19 from Neurological Overview
The COVID-19 from Neurological Overview Open
View article: Clinical and Electroencephalographic Findings in Patients with Sepsis-associated Encephalopathy and the Evaluation of Their Effects on Survival
Clinical and Electroencephalographic Findings in Patients with Sepsis-associated Encephalopathy and the Evaluation of Their Effects on Survival Open
Objective: Acute brain dysfunction is common in sepsis patients and is associated with increased mortality.This study aimed to investigate the clinical and electroencephalographic (EEG) findings of patients with acute neurological dysfunct…
View article: COVID-19 ve Epilepsi: Nöbetlere, Tedaviye ve Sosyal Yaşama Etkileri
COVID-19 ve Epilepsi: Nöbetlere, Tedaviye ve Sosyal Yaşama Etkileri Open
Coronavirus disease 2019 (COVID-19) can be spread rapidly and can be seen in a wide section of society at any age, affecting the whole society, as well as patients with epilepsy. A virus may cause neurological involvement, as well as syste…
View article: Correction to: Long-term follow-up of a large cohort with focal epilepsy of unknown cause: deciphering their clinical and prognostic characteristics
Correction to: Long-term follow-up of a large cohort with focal epilepsy of unknown cause: deciphering their clinical and prognostic characteristics Open
View article: Susceptibility to Juvenile Myoclonic Epilepsy Associated with the EFHC1 Gene: First Case Report in Turkey
Susceptibility to Juvenile Myoclonic Epilepsy Associated with the EFHC1 Gene: First Case Report in Turkey Open
Juvenile myoclonic epilepsy (JME), characterized by predominating myoclonic seizures, is one of the most common forms of genetic generalized epilepsy.Genetic studies in JME reported susceptibility associated with EFHC1 gene.A 26-year-old m…
View article: The Impact of Affective State on Quality of Life in Focal Epilepsy in Turkey
The Impact of Affective State on Quality of Life in Focal Epilepsy in Turkey Open
Context: Seizures and accompanying situations including social, medical, and psychiatric problems threaten the quality of life (QOL) in patients with epilepsy. The World Health Organization defines health is a state of complete physical, m…