Nésrine Elloumi
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View article: Investigating the Expression of LL-37 Antimicrobial Peptide in Autoimmune Bullous Disorders: Implications for Pemphigus
Investigating the Expression of LL-37 Antimicrobial Peptide in Autoimmune Bullous Disorders: Implications for Pemphigus Open
Objective: This study aimed to investigate the expression of the antimicrobial peptide cathelicidin LL-37 and discuss its role as a critical factor in developing pemphigus. Methods: The expression of LL-37 mRNA was assessed in individuals …
View article: Annexin A1 expression in Lupus Nephritis
Annexin A1 expression in Lupus Nephritis Open
Introduction: Lupus nephritis (LN) is an immune complex glomerulonephritis, caused by systemic lupus erythematosus. It is associated with an increase of morbidity and mortality. In LN, the immune responses dysregulation is one of the cruci…
View article: Tubular expression of Toll-like receptor 9 in lupus and primary membranous nephropathy
Tubular expression of Toll-like receptor 9 in lupus and primary membranous nephropathy Open
Introduction: Toll-like- receptors (TLR) control important aspects of innate and adaptive immune responses. Renal cells are among the non-immune cells that express (TLR). Therefore, their activation might be implicated in renal tubulo-inte…
View article: Evaluation of X chromosome inactivation in endemic Tunisian pemphigus foliaceus
Evaluation of X chromosome inactivation in endemic Tunisian pemphigus foliaceus Open
Background Almost 5% of the world's population develops an autoimmune disease (AID), it is considered the fourth leading cause of disability for women, who represent 78% of cases. The sex ratio when it comes to the most prevalent AID varie…
View article: Differential Expression of Anti-Inflammatory RNA Binding Proteins in Lupus Nephritis
Differential Expression of Anti-Inflammatory RNA Binding Proteins in Lupus Nephritis Open
Lupus nephritis (LN) is a type of immunological complex glomerulonephritis characterized by chronic renal inflammation which is exacerbated by infiltrating leukocytes and fueled by a variety of pro-inflammatory cytokines. A profound unders…
View article: Vitamin D status and <i>CYP27B</i>1‐1260 promoter polymorphism in Tunisian patients with systemic lupus erythematosus
Vitamin D status and <i>CYP27B</i>1‐1260 promoter polymorphism in Tunisian patients with systemic lupus erythematosus Open
Aim An association between serum vitamin D (Vit D) levels and systemic lupus erythematosus (SLE) has been reported by several studies that suggested the involvement of genetically determined characteristics of enzymes of vitamin D metaboli…
View article: Toll‐like‐Receptor Gene Polymorphisms in Tunisian Endemic Pemphigus Foliaceus
Toll‐like‐Receptor Gene Polymorphisms in Tunisian Endemic Pemphigus Foliaceus Open
Pemphigus foliaceus (PF) is considered to be caused by the combined effects of susceptibility genes and environmental triggers. The polymorphisms of Toll‐like receptors (TLRs) genes have been associated with the risk of various autoimmune …
View article: Olive trees response to lead stress: Exogenous proline provided better tolerance than glycine betaine
Olive trees response to lead stress: Exogenous proline provided better tolerance than glycine betaine Open
International audience
View article: Involvement of the IL23/Th17 Pathway in the Pathogenesis of Tunisian Pemphigus Foliaceus
Involvement of the IL23/Th17 Pathway in the Pathogenesis of Tunisian Pemphigus Foliaceus Open
Pemphigus foliaceus (PF) is a rare autoimmune skin disease caused by anti-Dsg1 pathogenic autoantibodies. It is considered as a Th2-mediated disease. Likewise, Th17 cells were recently described in the pathogenesis of the disease but their…
View article: HLA Class III: A susceptibility region to systemic lupus erythematosus in Tunisian population
HLA Class III: A susceptibility region to systemic lupus erythematosus in Tunisian population Open
Our results confirm the association between TNF and DRB1 polymorphisms and SLE. The association between alleles of D6S291 and SLE needs however to be verified by the analysis of other markers beyond this region.
View article: Relevant genetic polymorphisms and kidney expression of Toll-like receptor (TLR)-5 and TLR-9 in lupus nephritis
Relevant genetic polymorphisms and kidney expression of Toll-like receptor (TLR)-5 and TLR-9 in lupus nephritis Open
Summary Toll-like receptor (TLR) genetic polymorphisms may modify their expression causing inflammatory disorders and influencing both susceptibility and severity of lupus erythematosus. We aim to determine whether TLR-5 and TLR-9 gene pol…
View article: The Increased Expression of Toll-Like Receptor 4 in Renal and Skin Lesions in Lupus Erythematosus
The Increased Expression of Toll-Like Receptor 4 in Renal and Skin Lesions in Lupus Erythematosus Open
Toll-like receptor 4 (TLR-4), a bacterial lipopolysaccharide sensor, is an innate immunity essential modulator. It is expressed on both immune and non-immune cells and may contribute to the cutaneous and renal manifestations during lupus e…
View article: Enzymatic antioxidant responses and mineral status in roots and leaves of olive plants subjected to fluoride stress
Enzymatic antioxidant responses and mineral status in roots and leaves of olive plants subjected to fluoride stress Open
International audience