Explanipedia

The unveiled face of IEI: Children Cancer Hospital—Egypt (CCHE-57357) experience Open

Nesrine Radwan, Youssef Medany, Hanaa Rashad, Ahmed Elhemaly, Mahmoud Hammad , et al. · 2025

Background Inborn errors of immunity (IEI) are a heterogeneous group of different disorders characterized by a defect in the function and/or components of the immune system. Malignancy is the second common cause of death following recurren…

The Renin Inhibitor Aliskiren mitigates Diabetes mellitus induced Vascular Impairment of rats Open

Reem M Emam, Suzan A Khodir, Ahmed Mohamed Gaafar, Noha Abd El-aziz, Noha Noufal , et al. · 2025

Health-related quality of life among a group of Egyptian children with inborn errors of immunity: a cross-sectional study Open

Yehia El-gamal, Azza M. Youssef, A. M. El sayed, Nesrine Radwan · 2024

Newborn screening for inborn errors of immunity: The status worldwide Open

Herberto José Chong‐Neto, Nesrine Radwan, Antônio Condino‐Neto, Nelson Augusto Rosário Filho, José Antonio Ortega‐Martell , et al. · 2024

This pilot study showed that few countries have implemented NBS for IEI, despite the presence of immunology referral centers and the availability of hematopoietic stem cell transplantation and intravenous immunoglobulin replacement therapy…

African Society for Immunodeficiency (Asid) Guidelines for Diagnosis and Management of Inborn Errors of Immunity in Africa: Core Concept, Development and Initial Results Open

Rayan Goda, Ali Sobh, Galal Nermeen, Nesrine Radwan, Mohamed‐Ridha Barbouche , et al. · 2022

Background and aims The African Society for Immunodeficiency (ASID), looked to form concise region-friendly guidelines for the clinical diagnosis and management of Inborn Errors of Immunity (IEI). The main objective was to develop these gu…

KAT2B expression on CD4+T lymphocytes in pediatric systemic lupus erythematosus Open

Elham Hossny, Dalia El‐Ghoneimy, M. H. Hamza, Nesrine Radwan, Mariam abdelnaby · 2022

Impact of COVID-19 on children with rheumatic diseases: a retrospective cohort analysis Open

Rasha El‐Owaidy, Elham Hossny, Dalia El‐Ghoneimy, Zeinab El-Sayed, Shereen M. Reda , et al. · 2022

Background: Data concerning impact of COVID-19 on children with rheumatic disorders in developing countries are limited.Methods: We conducted a retrospective analysis, examining the medical records of 49 children (15 males, 34 females) wit…

Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry Open

Mahnaz Jamee, Gholamreza Azizi, Safa Barış, Elif Karakoç‐Aydiner, Ahmet Özen , et al. · 2022

Allergic manifestations of inborn errors of immunity and their impact on the diagnosis: A worldwide study Open

Zeinab El-Sayed, Dalia El‐Ghoneimy, José Antonio Ortega‐Martell, Nesrine Radwan, Juan C. Aldave , et al. · 2022

Impact of pediatric systemic lupus erythematosus on the health-related quality of life Open

Elham Hossny, Azza M. Youssef, Nesrine Radwan, Mohamed Al-Ashkar · 2022

Leukocytic dysregulation in children with type 1 diabetes: relation to diabetic vascular complications Open

Nouran Yousef Salah, Nesrine Radwan, Heba Mohamed Atif · 2022

Efficacy of Intravenous Immunoglobulin Replacement Therapy in Patients with Predominantly Antibody Deficiency Open

Shereen M. Reda, Mourad Alfy Ramzy, Hebat Allah MM Waheed El-din, Nesrine Radwan · 2021

Background Intravenous immunoglobulin G (IVIG) has been used as an antibody replacement therapy in primary immunodeficiency (PID) for more than 50 years. Most routinely, IVIG is used in patients with predominantly antibody deficiency such …

Serum interleukin-17 expression in a group of Egyptian patients with juvenile systemic lupus erythematosus Open

Nesrine Radwan, Mohamed Hamza, Islam Ghareeb, Mohamed Hisham · 2021

Background: Systemic lupus erythematosus (SLE) is a chronic multi-organ systemic autoimmune disease. Interleukin-17 (IL-17) is a powerful proinflammatory cytokine that is involved in the development of several autoimmune diseases, includin…

The Effect of Ketogenic Diet on Neutrophil Count Open

May Fouad Nassar, Yasmin G. El Gendy, Mohamed Hamza, Marwa Nasser Mohamed, Nesrine Radwan · 2021

Background The Ketogenic Diet (KD) is a high-fat, low-carbohydrate, and adequate-protein diet and a well-established treatment option for drug resistant childhood epilepsies. Neutrophils are important component of humans` innate phagocytic…

Visual field defect due to Hydroxychloroquine in systemic lupus erythematosus Open

Elham Hossny, Mona K Abdel Latif, Nesrine Radwan, Rou’ya A Gah Al-Rassoul · 2021

Background Hydroxychloroquine (HCQ) is used in the management of a variety of autoimmune disorders, with well-established role in dermatology and rheumatology. However, Hydroxychloroquine and chloroquine (CQ) have been associated with irre…

Outcome of Cyclophosphamide versus Mycophenolate Mofetil in Induction of remission in Pediatrics Lupus Nephritis Open

Ashraf A Salama, Shimaa Sobhy Mohamed, Nesrine Radwan · 2021

Background Systemic lupus Erythematous (SLE) is an autoimmune inflammatory disease characterized by antibodies directed against self-antigens, resulting in multi-organ damage. Up to 20% of cases are diagnosed during childhood with 55% of t…

Outcome of Hematopoietic Stem Cell Transplantation in patients with Mendelian Susceptibility to Mycobacterial Diseases Open

Nesrine Radwan, Zohreh Nademi, Su Han Lum, Terry Flood, Mario Abinun , et al. · 2021

Predisposition to mycobacterial infection is a key presenting feature of several rare inborn errors of intrinsic and innate immunity. Hematopoietic stem cell transplantation (HSCT) can be curative for such conditions, but published reports…

The Pediatric Allergy and Immunology Unit of Ain Shams University in times of SARS-CoV-2 pandemic: approach and challenges Open

Yehia El‐Gamal, Zeinab El-Sayed, Elham Hossny, Shereen M. Reda, Dalia El‐Ghoneimy , et al. · 2020

The Pediatric Allergy and Immunology (PAI) Unit of Ain Shams University, founded in 1988 by Professor Yehia El-Gamal and currently headed by Professor Shereen Reda, is a tertiary referral center for pediatric allergy, primary immunodeficie…

International Efforts to Save Healthcare Personnel during COVID-19. Open

Kawthar Mohamed, Nima Rezaei, Eduardo Rodríguez‐Román, Farzaneh Rahmani, Hongbo Zhang , et al. · 2020

Coronavirus disease 2019 (COVID-19) pandemic is a global challenge. Several governments of the world have decided to take drastic actions in order to combat the spread of the disease, including the closing of air, maritime and land borders…

Key diagnostic markers for autoimmune lymphoproliferative syndrome with molecular genetic diagnosis Open

Emese Ilyésné Molnár, Nesrine Radwan, Gábor Kovács, Hajnalka Andrikovics, Frances Henriquez , et al. · 2020

Autoimmune lymphoproliferative syndrome (ALPS) is a rare immunodeficiency caused by mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10). This study evaluated the clinical manifestations, laboratory findings, an…

Borderless collaboration is needed for COVID-19—A disease that knows no borders Open

Kawthar Mohamed, Eduardo Rodríguez‐Román, Farzaneh Rahmani, Hongbo Zhang, Mariya Ivanovska , et al. · 2020

An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the 'Save PDF' action button.

Newborn Screening for Primary Immunodeficiencies: The Gaps, Challenges, and Outlook for Developing Countries Open

Zeinab A. El-Sayed, Nesrine Radwan · 2020

Primary immunodeficiency diseases (PIDs) are genetically inherited diseases characterized by an increased susceptibility to infections, autoimmunity, lymphoproliferation, and malignancies. PIDs are under-diagnosed and the registered cases …

Clinical and genetic spectrum in 33 Egyptian families with suspected primary ciliary dyskinesia Open

Mahmoud R. Fassad, Walaa Shoman, Heba Morsy, Mitali Patel, Nesrine Radwan , et al. · 2019

Primary ciliary dyskinesia (PCD) is a rare genetic disorder of motile cilia dysfunction generally inherited as an autosomal recessive disease. Genetic testing is increasingly considered an early step in the PCD diagnostic workflow. We used…

Author response for "Clinical and genetic spectrum in 33 Egyptian families with suspected primary ciliary dyskinesia" Open

Mahmoud R. Fassad, Walaa Shoman, Heba Morsy, Mitali Patel, Nesrine Radwan , et al. · 2019

CXCR 3 expression on CD4+T cells and in renal tissue of pediatric systemic lupus erythematosus patients Open

Magid Ibrahim, Shereen El-Sayed, Ragia M Said, Nesrine Radwan, Mona Ahmed Ismail , et al. · 2019

Background: Pediatric systemic lupus erythematosus (pSLE) accounts forabout 20% of all cases of Systemic Lupus Erythematosus (SLE), withnephritis occurring in approximately 50% of the patients. Objective: toevaluate the expression of CXCR3…

Different Phenotypic Presentations of X-Linked Lymphoproliferative Disease in Siblings with Identical Mutations Open

Zohreh Nademi, Nesrine Radwan, Kanchan Rao, Kimberly Gilmour, Austen Worth , et al. · 2019

Clinical and immunological features in a cohort of patients with partial DiGeorge syndrome followed at a single center Open

Giuliana Giardino, Nesrine Radwan, Patra Koletsi, Deborah Morrogh, Stuart Adams , et al. · 2019

DiGeorge syndrome (DGS) is a primary immunodeficiency characterized by various degrees of T-cell deficiency. In partial DGS (pDGS), other risk factors could predispose to recurrent infections, autoimmunity, and allergy. The aim of this stu…

Eczema the hidden face of primary immunodeficiency diseases Open

Nesrine Radwan · 2019

Test yourself in eczema in primary immunodeficiency Open

Nesrine Radwan · 2019

Membrane endothelial protein C receptor expression in renal tissue of pediatric lupus nephritis patients Open

Magid Ibrahim, Shereen El-Sayed, Ragia M Said, Mona Ahmed Ismail, Naglaa S. Ahmed , et al. · 2019

Background: Lupus nephritis (LN) is more common and more severe is pediatric systemic lupus erythematosus (pSLE). Endothelial protein C receptor (EPCR) is an inducer of anti-apoptotic pathways in endothelial cells. Recent studies have tak…

Nesrine Radwan YOU? Author Swipe